Clinical trials: Pulpitis
Irreversible Pulpitis
Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars
The primary aim is to compare the behavior of the children during using conventional manual instrumentation versus rotary instrumentation by single rotary system for pulpectomy in primary molars through a Randomized Clinical…
- Trial name
- NCT07415694
- Testing
- Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan).
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Reversible Pulpitis
Direct Pulp Capping Agent on Human Pulp Tissue
This in- vivo study was conducted to evaluate the response of human pulp tissue following direct pulp capping using four different pulp capping agents in premolars scheduled for extraction in patients undergoing orthodontic…
- Trial name
- NCT06435065
- Testing
- Biodentine, Mineral Tri-Oxide Aggregate, THERACAL LC
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DR SURINDER SACHDEVA
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Molar Incisor Hypomineralisation, Irreversible Pulpitis
Pain Assessment Governing Partial or Full Pulpotomy of Immature Molars With Irreversible Pulpitis in Molar Incisor Hypomineralization
This randomized controlled clinical trial aims to evaluate and compare pain levels associated with partial pulpotomy (PP) and full pulpotomy (FP) in immature permanent first molars diagnosed with irreversible pulpitis.
- Conditions
- Molar Incisor Hypomineralisation, Irreversible Pulpitis, Immature Molars
- Trial name
- NCT07850986
- Testing
- pulpotomy for MIH affected immature PFMs, partial pulpotomy for MIH affected immature PFMs, pulpotomy for non-MIH affected immature PFMs
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Alaa Khafagy
Symptomatic Irreversible Pulpitis and Post Operative Pain
Laser-Assisted vs Conventional Total Pulpotomy in Symptomatic Irreversible Pulpitis
his randomized controlled clinical trial will compare laser-assisted total pulpotomy with conventional total pulpotomy in permanent molar teeth diagnosed with symptomatic irreversible pulpitis.
- Trial name
- LASERPULP (NCT07850258)
- Testing
- Conventional Total Pulpotomy, Laser-Assisted Total Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- meliksahgunduz
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Vital Pulp Therapies, Pulpotomy
Comparison of Sodium Hypochlorite Gel and Solution With and Without Nanoparticles for Postoperative Pain After Pulpotomy in Permanent Mandibular Molars
This randomized clinical trial aims to compare the effect of 2% sodium hypochlorite gel and solution, with and without chitosan nanoparticles, on postoperative pain following pulpotomy in mature permanent mandibular molars with…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Irriversible Pulpitis, Postoperative Pain
- Trial name
- NaOCl Pulpotom (NCT07774130)
- Testing
- Sodium Hypochlorite gel 2%, Sodium hypochlorite gel 2% with chitosan nano particles, Sodium hypochlorite solution 2% with chitosan nanoparticles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Irreversible Pulpitis With Apical Periodontitis
Full Pulpotomy in Permanent Teeth With Irreversible Pulpitis and Apical Periodontitis
This study will evaluate whether full pulpotomy can successfully treat mature permanent teeth with irreversible pulp inflammation and a periapical lesion.
- Trial name
- NCT07768852
- Testing
- Full pulpotomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Irreversible Pulpitis
Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis
This is a clinical trial to assess the treatment outcomes of pulpotomy in vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06149845
- Testing
- Full Pulpotomy
- Where
- 2 sites in Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Qatar University
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy vs. Pulpectomy in Vital Primary Molars With Symptomatic Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06183203
- Testing
- Pulpotomy, Pulpectomy
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nebu Philip
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy Versus Pulpectomy in Vital Primary Molars Diagnosed With Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06904781
- Testing
- Pulpotomy, Pulpectomy
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Qatar University
Irreversible Pulpitis (Toothache)
Laser Assisted Pulpotomy Versus MTA Pulpotomy in Permanent Teeth With Irreversible Pulpitis
This study compares two methods used during full pulpotomy, a treatment for teeth with deep tooth decay that has exposed the dental pulp.
- Trial name
- NCT07761962
- Testing
- Diode laser full pulpotomy, Sodium hypochlorite pulpotomy
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Deep Caries
Direct Pulp Capping Compared to Partial Pulpotomy in Carious Pulp Exposures
This a prospective randomized clinical trial that compare vital pulp therapy procedures in permanent teeth with carious pulp exposure.
- Trial name
- Pulp cap (NCT06495242)
- Testing
- Direct pulp capping and partial pulpotomy
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpitis in Permanent Teeth, Dental Caries Extending to Pulp
Pulp Inflammatory Markers and Outcome of Pulpotomy
This is a prospective clinical study that aims to investigate the level of inflammatory mediators in the inflamed dental pulp and its potential relationship to the outcome of full pulpotomy in mature permanent teeth with carious…
- Trial name
- pulpitis (NCT06960603)
- Testing
- Full pulpotomy
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Reversible Pulpitis, Irreversible Pulpitis
Biomarkers for Differentiating Reversible and Irreversible Pulpitis
This observational study aims to evaluate the role of inflammatory, oxidative stress, neurogenic, and immunological biomarkers obtained from pulpal blood in the differential diagnosis of normal pulp, reversible pulpitis, and…
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Healthy Pulp
- Trial name
- PULPBIOM (NCT07658742)
- Testing
- Pulpal Blood Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Safa
Symptomatic Irreversible Pulpitis (SIP)
COMT, MAOA, and SLC6A4 Polymorphisms and Inferior Alveolar Nerve Block Success
The purpose of this study was to evaluate the association between COMT, MAOA, and SLC6A4 genetic polymorphisms and the success of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in…
- Trial name
- NCT07697300
- Testing
- Inferior Alveolar Nerve Block with 4% Articaine
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pulpitis
Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With Pulpitis
The objective of this clinical trial is to evaluate whether buffered local anesthesia is more effective than conventional local anesthesia in reducing pain responses in school-aged children requiring dental treatment for…
- Trial name
- NCT07638254
- Testing
- Buffered Lidocaine with Epinephrine, idocaine with Epinephrine (Conventional)
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Pulpitis - Irreversible
Clinical and Radiographic Assessment of Bio C Repair, Biodentine and Mineral Trioxide Aggregate
The aim of this study is to assess Clinical and Radiographical effect of Bio C repair, Biodentine and Mineral Trioxide Aggregate when used as pulpotomy Agents in Immature Permanent Molars with Pulpits.
- Trial name
- NCT07522723
- Testing
- Biodentine, Bio C repair
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University