Clinical trials: Pulmonary Nodules
Lung Diseases, Interstitial, Pulmonary Nodule, Solitary
Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection
After performing VATS pulmonary wedge resections, a chest tube is routinely left in the pleural cavity to drain possible air leaks and fluid accumulations.
- Trial name
- NOTUBE (NCT00841750)
- Testing
- Do not leave a chest tube in the pleural cavity., Do leave a chest tube in the pleural cavity.
- Where
- 3 sites in Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle
Solitary Pulmonary Nodules, Lung Cancer
Plasma Metabolomics as a Tool to Distinguish PET-positive Malignant From PET-positive Benign Nodules
Positron emission tomography-computed tomography (PET-CT) is an important technique in lung cancer staging, where almost no lung lesion goes undetected.
- Trial name
- NCT07087080
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 350 people
- Sponsor
- Hasselt University
Lung Nodules, Ultrasound
Ultrahigh-frequency Ultrasonography (UHFUS) in Detection of Small Pulmonary Ground Glass Opacity (GGO)
The purpose of this study is to assess the feasibility of UHFUS on detection of GGOs in excised lung tissue and investigate UHFUS features of GGO in vitro. Each GGO was detected by palpation, UHFUS and open biopsy in sequence.
- Conditions
- Lung Nodules, Ultrasound, Detection Rate
- Trial name
- UHFUSGGO (NCT05994898)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Solitary Pulmonary Nodule, Oncology
18F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed Tomography
The study objectives are as follows: To determine the safety of trial 18F-2-fluoro-2-deoxy-D-glucose, produced by a new manufacturer, by surveillance for adverse events in patients having Positron Emission Tomography Computed…
- Conditions
- Solitary Pulmonary Nodule, Oncology, 18F-2-fluoro-2-deoxy-D-glucose, Adverse Event
- Trial name
- NCT04615156
- Testing
- 18F-2-fluoro-2-deoxy-D-glucose
- Volunteers
- 10,000 people
- Sponsor
- Eastern Health, Canada
Multiple Pulmonary Nodules
Fast Track Rehabilitation Following Video-assisted Lung Segmentectomy
Aim of this prospective randomized study is to assess the safety and efficacy of video-assisted lung segmentectomy (Group B) comparing with mini muscle-sparing thoracotomy (group A) during diagnostic process for pulmonary nodules.
- Trial name
- NCT01397045
- Testing
- VATS, Mini thoracotomy
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Theagenio Cancer Hospital
Pulmonary Function Assessment, Disease Free Survival
Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection
A method of ICG counterstaining localization under target artery occlusion without cutting，It's a new method of localization of small pulmonary nodules.
- Conditions
- Pulmonary Function Assessment, Disease Free Survival, NSCLC, Stage I
- Trial name
- NCT06404164
- Testing
- Wedge resection under watershed analysis method
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Lung Neoplasms, Lymph Node Excision
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules.
- Trial name
- NCT04631770
- Testing
- Systemic mediastinal lymph node dissection, Spared mediastinal lymph node dissection
- Where
- China
- Volunteers
- 1,362 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Tobacco Dependence Treatment, Lung Cancer Screening
ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening
Lung cancer is the leading cause of cancer-related death among Veterans with 90% of cases attributable to smoking. Lung cancer screening (LCS) combined with smoking cessation saves the most lives.
- Trial name
- ICARE-LCS (NCT06745258)
- Testing
- External Facilitation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Metastatic Pulmonary Nodules
Comparative Evaluation of MRI and MDCT for the Detection of Metastic Pulmonary Nodules
The purpose of this study is to apply the techniques of dynamic MRI imaging enhancement to research participants with one or more pulmonary nodule to determine if meaningful information about the nature of the nodule can be…
- Trial name
- NCT00751920
- Testing
- Enhanced MRI Scan
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- The Hospital for Sick Children
Lung Nodules
Pneumothorax Post CT Lung Biopsy
A CT scan is performed after a lung biopsy in order to detect a Pneumothorax. We postulate that CT is more useful than chest radiography
- Trial name
- NCT00188409
- Testing
- CT scan
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Hydatidiform Mole, Gestational Trophoblastic Neoplasia
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule ≥1.0cm will be randomized into 2 groups: A.
- Trial name
- NCT03785574
- Testing
- Follow up, chemotherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Lung Cancer
D-Lung: An Analytics Platform for Lung Cancer Based on Deep Learning Technology
Lung cancer is one of main cause of cancer death in worldwide, characterized of low 5-year survival rate of less than 20%. Pulmonary nodule is considered as the typical imaging manifestation in early stage of lung cancer.
- Trial name
- NCT04036903
- Testing
- computed tomography
- Where
- Hong Kong
- Volunteers
- 130 people
- Sponsor
- Chinese University of Hong Kong
SPN, Lung Cancer
Augmented Reality-assisted Localization of Solitary Pulmonary Nodules for Precise Sublobar Lung Resection
With the popularization of CT screening, the detection rate of small lung nodules has greatly increased. Therefore, the clinical thoracoscopic lung nodule biopsy and sub-lobectomy for radical resection of lung cancer are greatly…
- Trial name
- ARPL (NCT05162235)
- Testing
- Augmented Reality-assisted localization of solitary pulmonary nodule
- Volunteers
- 20 people
- Sponsor
- Shanghai Chest Hospital
Lung Neoplasms, Family Research
A Prospective Cohort of Pulmonary Ground Glass Nodules Patients With Family History.
The aim of the present prospective cohort study (GGN-F) is to study the family aggregation of pulmonary ground glass nodules via the questionnaire survey and to investigate the underlying genetic mechanism via the biobank.
- Trial name
- GGN-F (NCT04220268)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Guangdong Provincial People's Hospital
Pulmonary Nodules
A Pilot Study of PET-CT in the Assessment of Pulmonary Nodules in Children With Malignant Solid Tumors
Because the management of children with solid tumors hinges on the extent of disease, it is crucial to identify metastatic sites. Helical chest computed tomography (CT) is the standard method of excluding pulmonary metastases.
- Trial name
- NCT00629460
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- St. Jude Children's Research Hospital
Osteogenic Sarcoma
Accuracy of Deep-learning Algorithm for Detection and Risk Stratification of Lung Nodules
Osteosarcoma is regarded as most common malignant bone tumor in children and adolescents. Approximately 15% to 20% of patients with osteosarcoma present with detectable metastatic disease, and the majority of whom (85%) have…
- Trial name
- NCT04022512
- Testing
- computed tomography
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Neoplasms, Carcinoma
Radiofrequency Ablation of Malignant Pulmonary Nodules
The objective of this study is to evaluate the outcomes of radiofrequency ablation in the treatment of patients with malignant pulmonary nodules（not exceed 3cm ）who are not suitable candidates for or refuse surgical resection.
- Trial name
- NCT02629978
- Testing
- CT-guided percutaneous radiofrequency ablation
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Lung Cancer
Respiration Gated Laser Guided CT Lung Nodule Biopsy
The primary outcome of this study is to investigate the accuracy of respiration gated laser guided CT lung nodule biopsy through a prospective randomized trial using a bellows-based breath hold monitoring system.
- Trial name
- GENCTBIOPSY (NCT01236937)
- Testing
- Bellows-based breath hold device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Early Lung Cancer
Combined Diagnosis of CT and Exosome in Early Lung Cancer
This experiment has now collected 50 cases, all through CT chest scans and blood exosome detection. Twenty-two patients underwent surgical treatment and 14 tissue specimens were examined for cancer and paracancerous tissue…
- Trial name
- NCT03542253
- Testing
- Surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Lung Cancer (Diagnosis), Pulmonary Nodule Persistent
Multi-omics Detection Techniques for Differentiating Benign and Malignant Pulmonary Nodules
Research objective: To explore the clinical application effect of multi-omics detection based on flow cytometry analysis, single-cell data and images combined with clinical features in differentiating the benign and malignant…
- Trial name
- NCT07047573
- Testing
- PBMCS were isolated from the peripheral blood of hospitalized patients with pulmonary nodules and incubated with nanoparticles loaded with tumor antigens for a specific period of time to detect cancer
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zhao Jun