Clinical trials: Prospective Studies
Transplant-Related Disorder
Using the Composite Immune Risk Score to Assess and Modulate the Patient's Post-transplant Immune Reconstitution.
To assess the effectiveness of interventions including health monitoring and regular return follow-up reminders for patients with a high Composite Immune Risk Score.
- Trial name
- NCT06208137
- Testing
- Health monitoring and regular return follow-up reminders
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Invasive Aspergillosis, Antifungal Therapy
Treatment Duration of IPA
The goal of this observational study is to identify the duration of posaconazole-initiated antifungal treatment for IPA in patients with hematological malignancies and to explore the value of monitoring immune factors and cells…
- Trial name
- NCT06583512
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Peking University People's Hospital
Acute Lymphoblastic Leukemia, Pediatric
Vaccine Immune Recovery After Leukemia
This observational study aims to assess recovery of the immune system and immunity to vaccine-preventable diseases in children, adolescents, and young adults who recently completed treatment for acute lymphoblastic leukemia…
- Trial name
- VIRAL (NCT05622682)
- Testing
- Observational only: Serology and flow cytometry for ALL cohort participants, Observational only: Infection rates
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Osteoarthritis, Hip, Arthritis, Degenerative
A Retro-prospective Study of Total Hip Arthroplasty With EMPERION Modular Primary Stem in Australian Centres (HISTORIC)
This is a retro-prospective, single arm, sequential enrolment study to collect relevant clinical and radiological data in at least 156 subjects, at up to 10 sites in Australia, who have been implanted with the EMPERION™ Modular…
- Trial name
- HISTORIC (NCT02435420)
- Testing
- EMPERION Modular Primary Stem
- Where
- 8 sites in Australia
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Pregnancy Related, Cystic Fibrosis
Prospective Study of Pregnancy in Women With Cystic Fibrosis
In this study, the investigators aim to evaluate changes in lung function in women with cystic fibrosis (CF) during pregnancy and for 2 years after pregnancy based on exposure to highly effective cystic fibrosis transmembrane…
- Trial name
- MAYFLOWERS (NCT04828382)
- Where
- 40 sites in United States
- Volunteers
- 285 people
- Sponsor
- Amalia Magaret
Sickle Cell Disease
Observational Prospective Study Measuring the Impact of the Use of a Hypnotic Script Associated With Virtual Reality on the Pain of the Child's Sickle Cell During a Vaso-occlusive Crisis
The purpose of this study is to evaluate the effect of Virtual Reality induced Hypnosis on patients' pain scores, anxiety and the use of analgesics during a vaso-occlusive crisis
- Trial name
- DREPAReV (NCT04917120)
- Testing
- Virtual Reality
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rotator Cuff Tear, Fatty Atrophy
Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study
Rotator Cuff (RC) repair will be augmented with the injection of a human amniotic fluid derived allograft at the repair interface junction.
- Trial name
- NCT03379324
- Testing
- Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Applied Biologics, LLC
Infectious Complications Following Prostate Biopsy, Prostate Cancer
A Study Comparing Infectious Complications After Transperineal Prostate Biopsy With or Without Antibiotic Prophylaxis
Prostate biopsy performed through the perineal skin (the area between the testicles and the anus), known as a transperineal biopsy, is currently considered the standard procedure for diagnosing prostate tumors, having replaced…
- Trial name
- NCT07557901
- Testing
- No antibiotic prophylaxis for prostate biopsy, Antibiotic prophylaxis (fosfomycin-trometamol) for prostate biopsy.
- Where
- Slovakia
- Volunteers
- 300 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Hyperthyroidism
A Clinical Study of Hyperthyroidism in Children
This study intends to conduct a retrospective and prospective study on children with hyperthyroidism, and it is a non-intervention study to collect information on diagnosis and treatment and long-term follow-up of children with…
- Trial name
- NCT06570967
- Testing
- Methimazole(MMI)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shengjing Hospital
Psychotic Disorders, Family Members
Supporting Patients by Family Education in Psychotic Illness: A Prospective Cohort Study
Background: A lack of education, resources, and support for family carers of young adults with psychotic illnesses leaves them ill-equipped to support their loved one.
- Conditions
- Psychotic Disorders, Family Members, Anosognosia, Paranoia
- Trial name
- NCT05500001
- Testing
- Supporting Patients by Family Education in Psychotic Illness Group
- Where
- 4 sites in Canada
- Volunteers
- 113 people
- Sponsor
- University of Alberta
Analgesia, Post Operative Pain
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
We aim to investigate the value of vitamin B (B1, B6, B9, B12) on post-cesarean section analgesia in addition to the standard opioid-sparing multimodal regimen to achieve more robust analgesia with minimal side effects.
- Conditions
- Analgesia, Post Operative Pain, Cesarean Section
- Trial name
- NCT06446830
- Testing
- multimodal analgesia and vitamin B, standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Nausea and Vomiting, Postoperative
The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain
The hypothesis being tested in this study is that perioperative oral administration of dexamethasone, when compared to intravenous (IV) administration, offers a similar reduction in postoperative nausea and vomiting (PONV), and…
- Trial name
- NCT04563494
- Testing
- dexamethasone
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Colorado, Denver
Adolescent Idiopathic Scoliosis
Safety and Efficacy Study of Spinal Tethering
This study is an opportunity to gather long term safety and efficacy information from patients who have had their scoliosis treated via anterior vertebral body tethering (VBT).
- Trial name
- NCT02897453
- Testing
- The Spinal Tethering System
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Creatine Transporter Defect
Relevant Outcome Measures for Creatine Transporter Deficiency Patient
Creatine transport deficiency (CTD) is a rare genetic disorder related to pathogenic variants in the SLC6A8 gene, located on chromosome Xq28.
- Trial name
- CREAT_criteria (NCT06018519)
- Testing
- Clinical endpoints, Parental questionnaires, Quality of life scale
- Where
- France
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
0.5-14 Year Old Children With Nephroblastoma
Combination Therapy of Anthracyclines for Children With Nephroblastoma
This study aims to estimate the efficacy and side effects of study drugs in children with nephroblastoma who are treated with combination therapy.
- Trial name
- NCT03892330
- Testing
- Vincristine, Oxytetracycline/ Cyclophosphamide, Liposomal doxorubicin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Brain Tumor, Pediatric
Neurocognitive and Psychosocial Outcomes Among Pediatric Brain Tumor
This will be the first in-depth study to evaluate pretreatment and 12 months post-treatment, neurocognitive and psychological outcomes of children with brain tumor in Pakistan.
- Trial name
- PBT (NCT05709522)
- Testing
- Neurocognitive tools
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aga Khan University
Idiopathic Scoliosis
REFLECT Scoliosis System Post Approval Study
The purpose of this multi-center, prospective, single-arm registry Post-Approval Study (PAS) is to evaluate the radiographic and clinical outcomes of 100 patients with idiopathic scoliosis treated with the REFLECT™ Scoliosis…
- Trial name
- NCT06298812
- Testing
- REFLECT Scoliosis Correction System
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Globus Medical Inc
Muscle Loss, Extracellular Fluid Alteration
Ultrasound Detection of Body Composition in Critical Care
Objective assessment of the Changes in body composition of critically ill patients is very valuable. Ultrasound stands as a solution due to its portability, bedside availability, and radiation-free technology.
- Conditions
- Muscle Loss, Extracellular Fluid Alteration, Critical Illness, Pregnancy Complications
- Trial name
- NCT06728722
- Testing
- ultrasound detection of body composition
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Ain Shams University
Developmental Dysplasia of the Hip, Acetabular Bone Loss
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Total hip arthroplasty (THA) in patients with complex acetabular anatomy can be challenging because of abnormal bone structure, deformity, or bone loss.
- Conditions
- Developmental Dysplasia of the Hip, Acetabular Bone Loss, Acetabular Fracture
- Trial name
- NCT07904637
- Testing
- Conventional Imaging-Based Preoperative Planning, CT-Based 3D-Printed Pelvic Model-Assisted Planning
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Lateral Patellar Syndrome
To Compare the Clinical Efficacy of Arthroscopic Lateral Retinacular Release and Exercise Therapy in the Treatment of Lateral Patellar Crush Syndrome
One hundred patients with lateral patellar compression syndrome (LPCS) were recruited and divided into two groups: arthroscopic treatment group and rehabilitation conservative treatment group.
- Trial name
- NCT06988930
- Testing
- Control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.