Clinical trials: Propofol Dosage
Anesthesia
Ketamine and Propofol for Upper Endoscopy
The purpose of this study is to examine the dose-response relationship of ketamine in combination with propofol.
- Trial name
- NCT02295553
- Testing
- Ketamine, Propofol
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- The Hospital for Sick Children
Scoliosis
Susceptibility of Motor-Evoked Potentials to Varying Targeted Blood Levels of Dexmedetomidine
Reduction of the spinal cord injuries during scoliosis surgery is a major goal of the anesthesia and surgical team. Despite improvement in scoliosis surgery over the years, the development of neurological deficits remains the…
- Trial name
- NCT00671931
- Testing
- low dexmedetomidine, low propofol, high dexmedetomidine, low propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine Headache
Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric Patients
Propofol has been used in adult populations to treat migraines as an abortive agent. Investigators plan to investigate its efficacy as an abortive agent in the pediatric population when administered as a safe low-dose infusion.
- Trial name
- Propofol2014 (NCT02485418)
- Testing
- Propofol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Migraine Headache
Low-dose Propofol for Pediatric Migraine
Propofol, a general anesthetic, has been suggested to be effective for the treatment of migraine headaches in adults when used in subanesthetic doses (lower doses than those used for anesthesia or sedation).
- Trial name
- NCT01604785
- Testing
- Propofol, Standard Treatment
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Oregon Health and Science University
Adverse Reaction to Drug, Neonatal Disorder
Exploratory Propofol Dose Finding Study In Neonates
The aim of the study is to explore the optimal propofol dose in neonates receiving a single intravenous propofol bolus for endotracheal intubation during (semi-)elective INSURE (intubation-surfactant-extubation) procedure…
- Trial name
- NEOPROP (NCT01621373)
- Testing
- propofol administration
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
MRI Sedation
Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects ≥1 Month to <17 Years Undergoing MRI Scans
This is a randomized, double-blind, dose-ranging study of the efficacy and safety of dexmedetomidine (DEX) when used with propofol as needed, for procedural sedation of pediatric subjects ≥1 month to <17 years of age undergoing…
- Trial name
- NCT04237792
- Testing
- dexmedetomidine, propofol
- Where
- 23 sites in United States, Japan
- Volunteers
- 128 people
- Sponsor
- Pfizer
Spinal Puncture
Co-administration of Propofol and Remifentanil for Lumbar Puncture in Children
The objective of this study is to compare intraoperative and recovery parameters in patients who receive two different dose combinations of propofol and remifentanil in patients undergoing a lumbar puncture.
- Trial name
- NCT00405522
- Testing
- Propofol 2.0 mg/kg + Remifentanil 1.5 ug/kg, Propofol 4.0 mg/kg + Remifentanil 0.5 ug/kg
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- The Hospital for Sick Children
Emergence Agitation
Propofol in Emergence Agitation
The purpose of the study is to see if a small dose of propofol given intravenously (through a needle into a vein) at the end of anesthesia can make it less likely that children will be agitated as the come out of the anesthetic.
- Trial name
- NCT00535613
- Testing
- Propofol
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Wisconsin, Madison
Hematologic Diseases, Neoplasms
A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children
This study will examine whether the combination of two anaesthetic medications, propofol and remifentanil, is suitable for short duration surgical procedures, providing a shorter recovery time and fewer side effects than either…
- Trial name
- NCT00213239
- Testing
- Remifentanil
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- The Hospital for Sick Children