Clinical trials: Probiotics
Prader-Willi Syndrome
Probiotic Treatment for Prader-Willi Syndrome
A whole new research area studying the function of intestinal microorganisms, also known as gut microbiota, has emerged during the last decade.
- Trial name
- NCT04685057
- Testing
- Probiotic, Follow-up probiotic
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Fundació Sant Joan de Déu
Immune System Support
Effect of Probiotic Formula DE111® on Immune System in Preschool Children
Healthy preschool children will be recruited, gastrointestinal infection and respiratory infection symptoms will be followed during the 8-week treatment and 4-week follow-up period, to evaluate the effect of the used probiotic…
- Trial name
- IMMUNOFORM (NCT04077034)
- Testing
- Probiotic Formula Bacillus subtilis DE111®
- Where
- 5 sites in Slovenia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Gut Microbiota, Skin Microbiota
Lactobacillus Rhamnosus GG: Interaction With Human Microbiota and Immunity
Hypothesis: Probiotics have been used as novel adjunct therapeutic approach in atopic dermatitis. In addition to balancing the gut microecology and promoting host immune defences, specific probiotics might further aid in…
- Conditions
- Gut Microbiota, Skin Microbiota, Humoral Immune Responses, Severity of Atopic Dermatitis
- Trial name
- NCT01148667
- Testing
- Casein hydrolysate added with LGG, Infants drink casein hydrolysate without LGG
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital
Periodic Fever, Aphthous Stomatitis
Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)
The purpose of study is to see if adding probiotics to corticosteroid treatment for children with PFAPA could improve the health and daily of patients through reduction in febrile period frequency and length, along with…
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis
- Trial name
- PFAPA (NCT02535962)
- Testing
- Lactobacillus acidophilus and Bifidobacterium lactis
- Sponsor
- Connecticut Children's Medical Center
Myopia Progressing
Clinical Efficacy and Mechanism Exploration of MR-61 in Delaying the Progression of Myopia
To investigate whether probiotic MR-61 can assist in slowing down the progression rate of myopia (a prospective randomized controlled study).
- Trial name
- NCT07298824
- Testing
- Investigational Bifidobacterium Preparation MR-61
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Crohn's Disease
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease
Background VSL#3 has been reported as an effective adjuvant therapy both in inducing and maintaining remission in pediatric patients affected by Ulcerative Colitis.
- Trial name
- NCT01632462
- Testing
- VSL#3
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federico II University
Necrotizing Enterocolitis (NEC)
Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants
The goal of this clinical trial is to evaluate whether multi-strain probiotics of lactobacillus and bifidobacterium can prevent necrotizing enterocolitis (NEC) in preterm infants born at less than 32 weeks of gestation.
- Trial name
- NCT06810154
- Testing
- Multi-strain probiotics
- Where
- 4 sites in Canada
- Volunteers
- 2,170 people
- Sponsor
- University of Calgary
Immunity
Clinical Study on the Effect of Probiotic Compound Powder on the Immunity Improvement of Preschool Children
This is a randomized controlled trial, to evaluate the effect of WONDERLAB Probiotic Compound Powder on improving immunity of preschool children
- Trial name
- NCT05585021
- Testing
- Wonderlab Kids instant probiotics
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shenzhen Precision Health Food Technology Co. Ltd.,
Clinical Infection, Microbial Colonization
Effect of Gut Microbiota and Fecal Inflammatory Marker on Childhood Gastroenteritis
Childhood gastroenteritis establishes gastrointestinal disease and increase the economic burden, and the pediatric population is especially vulnerable to these gastrointestinal infections.
- Conditions
- Clinical Infection, Microbial Colonization, Gastroenteritis, Inflammatory Response
- Trial name
- NCT03856138
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diarrhea, Acute Respiratory Infection
Oral Supplement for Pregnant and Lactating Mothers
To assess protection against early life infections through supplementation of mothers during pregnancy to the newborns' growth, morbidity, immune status intra and extra-uterine.
- Trial name
- NCT01073033
- Testing
- milk supplement 1, milk supplement 2
- Where
- Philippines
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
URTI
Effects of Probiotics on Respiratory Tract Infections in Children: A Randomized, Placebo-Controlled Interventional Study
This study is a 14-day, randomized, double-blind, placebo-controlled trial involving children aged 3 months to 6 years who meet clinical diagnostic criteria for mild to moderate upper respiratory tract infection (URTI).
- Trial name
- NCT07498127
- Testing
- Probiotic
- Where
- 2 sites in China, Malaysia
- Volunteers
- 120 people
- Sponsor
- Min-Tze LIONG
ADHD
Probiotic Supplementation in Children With ADHD
This randomised, placebo controlled trial explores the effects of supplementation with a probiotic drink (kefir) in children diagnosed with ADHD on behaviour, sleep, attention and the gut microbiome.
- Trial name
- NCT05155696
- Testing
- Experimental: Kefir probiotic drink (supplied by Nourish)
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Respiratory Tract Infections
Impact of Probiotic Use on Immune Cell Function in Children
Probiotics are microorganisms that are believed to provide health benefits when consumed. The term probiotic is currently used to name ingested microorganisms associated with beneficial effects to humans and animals.
- Trial name
- NCT02687503
- Testing
- Probiotic
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Wisconsin, Madison
Gingivitis
Clinical Effect of Lactobacillus Reuteri in Treatment of Gingivitis
The aim of this randomized placebo- controlled clinical trials is to evaluate the effects of Lactobacillus reuteri containing probiotic lozenges as an adjunct to scaling and root planning (SRP).
- Trial name
- NCT02801773
- Testing
- Treatment Gingivitis with Probiotic, Treatment Gingivitis conventional
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Microbial Colonization
Effect of Probiotics on Infant's Fecal Microbiota Composition
Randomized clinical trial to evaluate the effect of two probiotic strains which belong to Bifidobacterium Longum and Pediococcus pentosaceus species on fecal microbiota composition in healthy infants.
- Trial name
- BABYCARE (NCT05524649)
- Testing
- Food Supplement 1, Food Supplement 2
- Where
- 2 sites in Mexico, Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Gut Microbiota
Impact of Probiotics Supplement on the Gut Microbiota in Caesarean-born Infants
The purpose of this study is to evaluate the effect of probiotics on the gut microbiota of infants born by cesarean section.
- Trial name
- NCT05086458
- Testing
- probiotics
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Children
Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children
The investigators believe a readily available drink containing a high dose of probiotics has the potential to improve compliance through many of these mechanisms.
- Trial name
- NCT01652287
- Testing
- BB-12 supplemented strawberry yogurt, Strawberry flavored yogurt
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Gastroenteritis
Efficacy of Two Probiotic Preparations in Children With Acute Diarrhoea
The purpose of this study is to determine which of two different preparations of probiotics is effective in the treatment of acute viral diarrhoea in children.
- Trial name
- NCT02080130
- Testing
- Saccharomyces boulardii, Probiotics combination
- Where
- Mexico
- Sponsor
- Sinaloa Pediatric Hospital
Antibiotic-associated Diarrhea
Efficacy of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders
To assess the effect of a probiotic product, when co-administered with antibiotics, on gastrointestinal symptoms following antibiotic treatment in children.
- Trial name
- NCT02722993
- Testing
- Probiotics
- Where
- Poland
- Volunteers
- 117 people
- Sponsor
- Probi AB
Children With Allergic Rhinitis
Effectiveness of Probiotics in Relieving Allergic Rhinitis in Children
To evaluate the clinical efficacy of probiotic gummies in the trial of allergic rhinitis in children compared to placebo, as well as the modulating effect on gut microbiota, serum metabolic profile, and occurrence of adverse…
- Trial name
- NCT06676111
- Testing
- Probiotic
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Wecare Probiotics Co., Ltd.