Clinical trials: Pilot Study
Survivors of Childhood Cancer, Alopecia
A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors
This study will test whether minoxidil taken by mouth (oral minoxidil) can improve hair loss caused by cancer treatment in children and young adults.
- Trial name
- NCT05778825
- Testing
- Oral Minoxidil
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Type 1 Diabetes
Cord Blood Plus Vitamin D and Omega 3s in T1D
In this pilot study the investigators are trying to see if a single intravenous infusion of autologous (self) cord blood cells followed by 1 year of daily vitamin D and omega 3 fatty acid supplementation can preserve beta cell…
- Trial name
- NCT00873925
- Testing
- Autologous UCB, Omega 3 FA, Vitamin D
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Self Esteem, Quality of Life
First Evaluation of COMET-Y
The goal of this pilot study is to evaluate COMET-Y in 22 adolescents (11-18 years) with various mental health problems and low self-esteem.
- Trial name
- COMET-Y (NCT06343740)
- Testing
- COMET-Y
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Accare
Spinal Muscular Atrophy
Outpatient Rehabilitation Intervention for Young Children With SMA
An outpatient rehabilitation program for children (6 months to less than 6 years old) with Spinal Muscular Atrophy (SMA) treated with genetic based therapies is being studied.
- Trial name
- NCT05638750
- Testing
- Rehabilitation Intervention
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
In-stent Restenosis
Pilot Study of the Coronary Spur Stent for In-stent Restenosis (DEEPER CORONARY)
To demonstrate acceptable short term safety rates of the Drug-eluting Coronary Spur Stent System as a primary treatment for coronary in-stent restenosis.
- Trial name
- NCT06117150
- Testing
- Drug-eluting Coronary Spur Stent System
- Where
- 2 sites in New Zealand
- Volunteers
- 9 people
- Sponsor
- ReFlow Medical, Inc.
Drug/Agent Toxicity by Tissue/Organ, Leukemia
Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy
RATIONALE: Silymarin (milk thistle extract) is an herb that may be effective in treating liver disorders caused by cancer therapy.
- Trial name
- NCT00055718
- Testing
- silymarin
- Where
- 8 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Infertility, Female
CAPA-IVM Versus STANDARD IVM
The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .
- Trial name
- NCT03921710
- Testing
- CAPA-IVM, Standard-IVM
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Mỹ Đức Hospital
Music Therapy
The Effects of Pacifier Activated Lullaby in VLBW Preterm Infants
Music and music therapy, live or recorded, has been introduced in the Neonatal Intensive Care Unit (NICU) of the Del Ponte hospital in Varese in addition to standard medical and nursing care, to improve premature neonates'…
- Trial name
- PAL (NCT04337476)
- Testing
- The effects of Pacifier Activated Lullaby in very low birth weigt preterm infants. An italian music therapy intervention
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
EBV Emia and EBV Positive PTLD After Allogenic HSCT
EBV-TCR-T Cells for EB Virus Infection After HSCT
This is a single center, single arm, open-label, phase I study to evaluate the safety and efficacy of EBV-TCR-T cells in patients with EB virus infection after HSCT.
- Trial name
- NCT04156217
- Testing
- EBV-TCR-T cells
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Hebei Yanda Ludaopei Hospital
Hidradenitis Suppurativa
Pilot Study on Botulinum Toxin B as Treatment for Hidradenitis Suppurativa
Randomized double blind placebo controlled pilot study/proof of concept-study to see if intradermal injection with Botulinum toxin B is an effective treatment of Hidradenitis suppurativa
- Trial name
- NCT03103074
- Testing
- Botulinum B Toxin
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
HIV, Sexually Transmitted Diseases
HIV and Sexually Transmitted Infection Prevention Intervention in the Northwest Territories
Indigenous youth are disproportionately represented in new HIV infection rates in Canada. Limited studies have evaluated longitudinal effects of arts-based approaches to HIV prevention with youth.
- Trial name
- NCT02743026
- Testing
- FOXY
- Where
- Canada
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Wiskott-Aldrich Syndrome
Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome
The Wiskott-Aldrich Syndrome (WAS) is an inherited disorder that results in defects of the blood and bone marrow. It affects boys because the genetic mistake is carried on the X chromosome.
- Trial name
- NCT01410825
- Testing
- Retrovirus-mediated gene transfer
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- David Williams
Catheter-related Bloodstream Infection, Preterm
Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates: a "LOOSEN" Pilot Study
Epicutaneo-caval catheters (ECCs) are widely used in neonatal intensive care units (NICUs). They are small catheters inserted via superficial veins of the limbs or scalp using direct vein visualization The pathogenic…
- Conditions
- Catheter-related Bloodstream Infection, Preterm, Catheter Infection, Catheter Complications
- Trial name
- LOOSEN (NCT05729321)
- Testing
- neutrox
- Where
- 2 sites in Italy
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Inflammatory Bowel Diseases
Effects of Exclusive Enteral Nutrition on the Microbiome in Pediatric Inflammatory Bowel Disease
Children with Crohn's disease can be effectively treated by remaining on a single-formula diet for 8 continuous weeks. This dietary therapy is known as "exclusive enteral nutrition" (EEN).
- Trial name
- NCT02521064
- Testing
- Exclusive Enteral Nutrition (EEN), Prednisone
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- McMaster Children's Hospital
Tic Disorders, Tourette Syndrome
Online Remote Behavioural Intervention for Tics (ORBIT)
Online Remote Behavioural Intervention for Tics (ORBIT). Primary objective: to evaluate the clinical effectiveness of BiP Tic, a therapist-guided, parent-assisted, internet-based behavioural therapy intervention for tics in young…
- Trial name
- ORBIT (NCT03483493)
- Testing
- Exposure Response Prevention for tics, Psychoeducation for tics
- Where
- United Kingdom
- Volunteers
- 224 people
- Sponsor
- Nottinghamshire Healthcare NHS Trust
Cerebral Palsy
Therapeutic Dance Intervention for Children With Cerebral Palsy
Children with cerebral palsy (CP) have motor impairments that may limit participation in standard physical activity (PA) programs. Adapted PA interventions may help address this gap.
- Trial name
- NCT03681171
- Testing
- Therapeutic Dance
- Volunteers
- 9 people
- Sponsor
- Shlomit Aizik
Autism Spectrum Disorder, Language Delay
Implementation of Incredible Years for Autism and Language Delay Program in Spain
Children with autism spectrum disorders (ASD) usually present coexisting problems in emotion and behavior regulation, similarly as premature children with communication or socialization difficulties.
- Conditions
- Autism Spectrum Disorder, Language Delay, Prematurity
- Trial name
- FS (NCT04358484)
- Testing
- Incredible Years - ASD and Language Delay®
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Fundació Sant Joan de Déu
Infantile Colic
Preliminary Efficacy and Safety Study of Oral Nepadutant in Infant With Colic Not Responding to Conventional Treatment
This phase IIa study is designed as a multi-centre, single country, randomised, double-blind, placebo controlled study in three parallel groups, with the aim to evaluate the efficacy and safety of Nepadutant given at two oral…
- Trial name
- nocry-a (NCT01309009)
- Testing
- Nepadutant oral solution
- Sponsor
- Menarini Group
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Pain
Tetracaine Compared to Placebo for Reducing Pain With Palivizumab - A Pilot Study
This is a small study known as a pilot study. This pilot study is being done to see if a difference in pain from intramuscular palivizumab injection can be detected if tetracaine a topical numbing gel is used compared to no…
- Trial name
- NCT00484393
- Testing
- tetracaine 4% gel
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Fraser Health