Clinical trials: Peripheral Artery Disease
Peripheral Artery Disease
Patient Centered Home Exercise Program for Peripheral Artery Disease
The purpose of this study is to determine the effects of a home-based exercise intervention on walking ability in people with peripheral artery disease.
- Trial name
- NCT02462824
- Testing
- Home-based exercise intervention
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Peripheral Arterial Disease
BRAVO: Biomarker Risk Assessment in Vulnerable Outpatients
The investigators hypothesize that among people with lower extremity peripheral artery disease (PAD), biomarker levels are higher during time periods immediately preceding an acute coronary event compared to time periods not…
- Trial name
- BRAVO (NCT02276781)
- Where
- 6 sites in United States
- Volunteers
- 595 people
- Sponsor
- Northwestern University
Peripheral Arterial Disease (PAD)
Zilver Flex Post-Market Study in Japan
Japanese post market clinical study of the Zilver Flex device.
- Trial name
- NCT02254356
- Testing
- Zilver Flex Bare Metal Stent
- Where
- Japan
- Volunteers
- 239 people
- Sponsor
- Cook Group Incorporated
Cardiovascular Diseases, Peripheral Vascular Diseases
Improving Functioning in Peripheral Arterial Disease
The purpose of this study is to compare the effects of nutrition, a supervised treadmill exercise program, and supervised progressive resistance training program on peripheral arterial disease.
- Trial name
- NCT00106327
- Testing
- Exercise, Diet
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Northwestern University
Peripheral Artery Disease
DUAL Pathway Inhibition to Improve Endothelial Function in Peripheral Artery Disease
Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis, causing patients to be at high risk of major adverse cardiovascular and limb events.
- Trial name
- DUAL-PAD (NCT04218656)
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet
- Where
- 2 sites in Netherlands
- Volunteers
- 159 people
- Sponsor
- Radboud University Medical Center
Matched-Pair Analysis, Blood Gas Analysis
Mathematical Arterialization of Venous Blood Gas
Objective: Arterial blood gas (ABG) analysis is essential in the clinical assessment of potential acutely ill patients. Venous to arterial conversion (v-TAC), a mathematical method, has recently been developed to convert…
- Conditions
- Matched-Pair Analysis, Blood Gas Analysis, Emergency Service, Hospital
- Trial name
- NCT03309410
- Testing
- Venous to arterial conversion (v-TAC)
- Volunteers
- 30 people
- Sponsor
- Aalborg University
Critical Limb Ischemia, Arterial Occlusive Disease
Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
The hypothesis behind the trial is the concept that Pregabalin is effective in reducing pain at rest in lower limb ischemia, and the study evaluates active treatment or placebo added to the regular pain regimens for these…
- Conditions
- Critical Limb Ischemia, Arterial Occlusive Disease, Pain, Ischemia
- Trial name
- NCT00403780
- Testing
- pregabalin
- Where
- 3 sites in Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Peripheral Arterial Disease
Randomized Clinical Trial for Ewing Amputation in the VA
This study follows the Pilot Investigation of Ewing Amputation for Veterans with PAD Undergoing a Below Knee Amputation. The 2 year pilot feasibility phase has concluded recruitment and enrollment.
- Trial name
- NCT05437562
- Testing
- Ewing Below Knee Amputation, Standard Below Knee Amputation
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Peripheral Arterial Disease
GORE® VIABAHN® Endoprosthesis Post-Marketing Surveillance Study (JPS 16-03)
This study will confirm device efficacy and safety in the clinical setting after the launch of the GORE® VIABAHN® Endoprosthesis for the treatment of symptomatic peripheral arterial disease in the superficial femoral arteries.
- Trial name
- NCT04706273
- Testing
- GORE® VIABAHN® Endoprosthesis
- Where
- Japan
- Volunteers
- 321 people
- Sponsor
- W.L.Gore & Associates
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Peripheral Arterial Disease
Vitamin D and Walking Ability in Patients With Peripheral Artery Occlusive Disease
The purpose of this study is to determine whether the intake of Vitamin D has a positive effect on walking ability of patients with peripheral artery occlusive disease.
- Trial name
- NCT01559974
- Testing
- Cholecalciferol
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University Hospital, Basel, Switzerland
Oxygen Consumption, Aortic Aneurysm
Study of Post-operative Oxygen Consumption Following Vascular Surgery
To define any changes in whole body oxygen consumption that occur following major vascular surgery (open aortic aneurysm surgery; endovascular aortic aneurysm repair; and infra-inguinal lower limb revascularisation procedures).
- Conditions
- Oxygen Consumption, Aortic Aneurysm, Peripheral Arterial Disease
- Trial name
- NCT01327820
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- NHS Lothian
Peripheral Arterial Occlusion or Emboli
Case Review of the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery
The primary objective of this retrospective case review study is to determine the safety and effectiveness of the Penumbra and Indigo Systems for mechanical thrombectomy in a cohort of patients with confirmed peripheral or…
- Trial name
- PRISM (NCT02085551)
- Testing
- Mechanical Thrombectomy by the Indigo System
- Where
- 5 sites in United States
- Volunteers
- 85 people
- Sponsor
- Penumbra Inc.
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Peripheral Arterial Disease, Claudication
THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease
The purpose of this study is to understand the effects of fish oil supplement (containing parts of omega-3 fatty acids) on inflammation.
- Conditions
- Peripheral Arterial Disease, Claudication, Claudication, Intermittent, Vascular Occlusion
- Trial name
- NCT02719665
- Testing
- SPM Emulsion, Dose-modality, SPM Softgel, Dose-Modality
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Peripheral Arterial Disease(PAD), Aneurysmal Disease
Transverse Versus Longitudinal Groin Incision in Vascular Surgery
The purpose of the study is to examine whether incision type has an influence on the development of groin wound complications after operation in the groin in vascular surgery.
- Trial name
- NCT06631378
- Testing
- Transverse groin incision, Longitudinal incision
- Where
- Denmark
- Volunteers
- 232 people
- Sponsor
- Kolding Sygehus
Peripheral Arterial Disease, Symptomatic Femoropopliteal Lesions
The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)
The purpose of this post-market surveillance study will be to evaluate the real-world use of the DETOUR System in treated patients with symptomatic femoropopliteal lesions from 200 mm to 460 mm in length with chronic total…
- Trial name
- PTAB1 (NCT06315023)
- Testing
- DETOUR System
- Where
- 10 sites in United States
- Volunteers
- 450 people
- Sponsor
- Endologix
Peripheral Arterial Disease, Claudication
Effects of Passive Muscle Stretching on Vascular Function and Symptoms of PAD
Patients with peripheral arterial disease often have walking impairment due to insufficient oxygen supply to lower extremity skeletal muscle.
- Trial name
- NCT03288181
- Testing
- Muscle Stretch
- Volunteers
- 13 people
- Sponsor
- Tallahassee Research Institute, Inc.
Intracranial Aneurysm, Brain Arterial Disease
Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
BALT has designed an electronic platform to continue collecting clinical data as part of the post-marketing clinical follow-up of its devices.
- Conditions
- Intracranial Aneurysm, Brain Arterial Disease, Acute Ischemic Stroke, Peripheral Vascular Diseases
- Trial name
- EVIDENCE (NCT04927156)
- Testing
- BALT medical devices
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Balt Extrusion
Intermittent Claudication, Peripheral Arterial Disease
York Study of Unloading Shoes for Vascular Intermittent Claudication
Some people experience a cramp-like leg pain during walking that is relieved only by rest. This is called intermittent claudication (IC) and it is a common symptom of peripheral arterial disease.
- Trial name
- YORVIC (NCT02505503)
- Testing
- Unloading shoes, Unadapted control shoe
- Where
- 2 sites in United Kingdom
- Volunteers
- 38 people
- Sponsor
- York Teaching Hospitals NHS Foundation Trust