Clinical trials: Perinatal Care
Birth Outcome, Adverse, Labor Long
How Long Can Labor Last? Person Centred Care During Labor to Increase Safety for Women and Newborn
"How long will my labor last" is a very common question for midwives who care for women during birth. To evaluate safe labor duration largely determines management and care during birth.
- Conditions
- Birth Outcome, Adverse, Labor Long, Labor Complication, Maternal Injury
- Trial name
- NCT06420453
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Karolinska Institutet
Pregnancy Related, Perinatal Depression
Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care
This study will provide high-quality, representative data on the capacity of Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care (EleVATE GC) to reduce perinatal depression, preterm birth, and…
- Trial name
- EleVATE GC (NCT04838210)
- Testing
- EleVATE Group Care, Individual Prenatal Care
- Where
- 4 sites in United States
- Volunteers
- 416 people
- Sponsor
- Washington University School of Medicine
Perinatal Mortality
Low-dose High-frequency Training of Facility Health Care Providers in Mali
This 3-arm cluster randomized trial (C-RCT) has the following objectives: Primary Aim To evaluate the effectiveness of an on-site case-based focused low-dose high-frequency training strategy in a primary health care facility…
- Trial name
- NCT03656237
- Testing
- Usual Training, Audits + LDHF Training
- Where
- Mali
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Perinatal Problems, Still Births
Community-based Perinatal and Newborn Care in Gilgit District, Northern Areas, Pakistan: an AKU-AKHSP Collaboration
There is limited evidence from community-based interventions to guide the development of effective maternal, perinatal and newborn care practices and services in developing countries.
- Conditions
- Perinatal Problems, Still Births, Neonatal Deaths
- Trial name
- NCT02412293
- Testing
- Health Education & Promotion, Training of Health Workers, Community Mobilization
- Where
- Pakistan
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Kangaroo Mother Care, Preterm Infant
Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa
We will conduct an individually randomised, controlled, superiority trial with two parallel groups; an intervention arm allocated to receive KMC and a control arm receiving 'standard' care.
- Conditions
- Kangaroo Mother Care, Preterm Infant, Death; Neonatal, Hypothermia, Newborn
- Trial name
- OMWaNA (NCT02811432)
- Testing
- Kangaroo mother care, Standard care
- Where
- 4 sites in Uganda
- Volunteers
- 2,221 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Congenital Heart Disease, Fetal Heart Disorder
Perinatal Cardiology: Bridging Obstetric and Neonatal Care in CHD
This prospective observational study aims to evaluate the agreement between prenatal fetal echocardiographic diagnoses and postnatal diagnoses of congenital heart disease, and to assess the impact of prenatal diagnosis status on…
- Conditions
- Congenital Heart Disease, Fetal Heart Disorder, Neonatal Disease, Fetal Disease
- Trial name
- NCT07820163
- Volunteers
- 115 people
- Sponsor
- Assiut University
Episiotomy, Pregnancy
Improving Perinatal Care in Latin America
Many obstetrical interventions used in Latin America, as in other parts of the world, have been shown to be ineffective or harmful, while effective interventions remain underutilized.
- Trial name
- NCT00070720
- Testing
- Opinion Leaders, Academic Detailing, Reminders, and Feedback
- Where
- Uruguay
- Volunteers
- 21,780 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
Prenatal Care, Maternal Health Services
Faith Leaders Advocating for Maternal Empowerment (FLAME)
In 2015, the average Ethiopian woman had a 1 in 64 lifetime risk of death due to complications of childbirth and 87,414 newborns died before their 28th day of life.
- Conditions
- Prenatal Care, Maternal Health Services, Perinatal Care
- Trial name
- NCT04039932
- Testing
- FLAME
- Where
- Ethiopia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Washington
Maternal Care Patterns, Pregnancy Related
Cash Benefits and Reproductive/Perinatal Health
During the first two years of the COVID-19 pandemic, the City of Chelsea, Massachusetts held a lottery to allocate cash benefits to its residents for ten months.
- Conditions
- Maternal Care Patterns, Pregnancy Related, Miscarriage
- Trial name
- NCT05782660
- Testing
- Cash Benefit, No Cash Benefit
- Where
- United States
- Volunteers
- 3,615 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Perinatal Depression
Clinical and Cost-effectiveness of an Online Self-help Intervention and a Face-to-face Intervention Versus Usual Care in Mothers at Moderate Risk for Perinatal Depression
The perinatal period (pregnancy and the first postnatal year) (O'Hara \& Wisner, 2014) involves important changes and considerable challenges for parents (Milgrom \& Gemmill, 2015).
- Trial name
- MaMHI (NCT07027761)
- Testing
- Online self-help, Maternal Mental Health Intervention (MaMHI), Usual Care
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Cephalohematoma
Needle Aspiration for Large Cephalohematoma
The cephalohematoma is a common pathology of newborns. Observation is the primary treatment for the most of small uncomplicated cephalohematoma.
- Trial name
- NCT03875456
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Montpellier
Perinatal Depression
Hybrid Health Education Intervention Integrated Within a Mental Health Package for Adolescent Perinatal Depression
The goal of this clinical trial is to develop a hybrid E-zine health education intervention integrated within a mental Health package for adolescent perinatal depression.
- Trial name
- E-zineMH (NCT06154655)
- Testing
- E-zine
- Where
- 2 sites in Nigeria
- Volunteers
- 63 people
- Sponsor
- University of Ibadan
Depression, Pregnancy
Care Managers for Perinatal Depression (CMPD)
The investigators will evaluate effects of introducing the care manager on: 1. Patient receipt of timely diagnosis and initiation of treatment for major depression (diagnosis within 2 weeks of screening and treatment within 1…
- Trial name
- CMPD (NCT01773629)
- Testing
- Intervention, Control
- Where
- 4 sites in United States
- Volunteers
- 194 people
- Sponsor
- Lancaster General Hospital
Extreme Prematurity - Less Than 28 Weeks, Infant, Extremely Premature
The UK 22 Week Study
In the UK, babies born at 22 weeks of pregnancy have only been offered survival-focused care (sometimes called resuscitation or stabilisation) since 2019.
- Conditions
- Extreme Prematurity - Less Than 28 Weeks, Infant, Extremely Premature, Neonatal and Perinatal Conditions, Intensive Care, Neonatal
- Trial name
- NCT07616778
- Testing
- Not applicable (observational study)
- Where
- 50 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Pregnancy Related
The OPTIMIZE Study: Optimizing Patient Navigation for Perinatal Care
This study will develop and test an intervention, called OPTIMIZE, which includes the use of a perinatal checklist by clinic staff and provision of patient navigation support to African American pregnant women.
- Trial name
- NCT04261894
- Testing
- OPTIMIZE
- Where
- United States
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prenatal Care
HIV With Innovative Group Antenatal Care in Two African Countries
The quality of antenatal care (ANC) in much of sub-Saharan Africa is constrained by severe resource and staffing shortages. The investigators adapted and piloted an evidence-based model of group antenatal care as an innovative…
- Trial name
- NCT02999334
- Testing
- Group Antenatal Care
- Volunteers
- 218 people
- Sponsor
- University of Illinois Chicago
Maternal Complication of Pregnancy, Newborn Morbidity
Scaling up Evidence Based MNCH Interventions : A Quasi Experimental Study Umeed e Nau (UeN) Project
The Umeed-e-Nau (UeN) initiative aims to support the introduction, scale up, and further piloting of high quality and high impact interventions to improve Maternal, Newborn And Child Health (MNCH)in Pakistan by harnessing the…
- Conditions
- Maternal Complication of Pregnancy, Newborn Morbidity, Perinatal Problems
- Trial name
- UeN (NCT04184544)
- Testing
- Improving of quality of care at health facility and outreach level
- Where
- Pakistan
- Volunteers
- 5,000,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pregnancy, Living in an Isolated Area
Optimizing Access to Care During Pregnancy in Rural Areas in a Perinatal Health Network
Pregnant women who live in rural area have fewer prenatal consultations. It has been demonstrated that maternal and neonatal morbidity and mortality increase if time travel to a maternity ward is longer than 30 min.
- Trial name
- OPTI'SOINS (NCT04823104)
- Testing
- Home visitation
- Where
- France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Clermont-Ferrand
Infant, Extremely Premature, Obstetric Labor, Premature
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
The goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveries and infants admitted to…
- Conditions
- Infant, Extremely Premature, Obstetric Labor, Premature, Premature Birth, Intensive Care, Neonatal
- Trial name
- NCT05685745
- Where
- 59 sites in United States, Australia and 6 more
- Volunteers
- 5,000 people
- Sponsor
- The University of Texas Health Science Center, Houston