Clinical trials: Periapical Lesion Healing
Periapical Diseases, Root Canal Infection
Comparing Efficacy of a Stainless-steel Rotary File with Two Nickel-titanium Systems on Periapical Lesion Healing
Background: This study used cone-beam computed tomography (CBCT) to compare a stainless-steel Tornado file system with OneShape and WaveOne rotary systems for biomechanical canal preparation as indicated by the healing of…
- Trial name
- NCT06752837
- Testing
- Tornado rotary system, WaveOne rotary system, OneShape rotary system
- Where
- 2 sites in Lebanon
- Volunteers
- 60 people
- Sponsor
- Beirut Arab University
Periapical Periodontitis
Biodentine as an Apical Plug in Immature Permanent Molars
Following the randomization procedure, patients will be divided into 2 groups (12 immature molars in each group): Group I will be treated with MTA as apical plug, whereas group II will be treated with Biodentine as apical plug.
- Trial name
- NCT05719987
- Testing
- Biodentine, MTA
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Damascus University
Periapical Periodontitis, Periradicular Lesion
Accuracy and Healing Outcomes of Endodontic Surgery Using a Static Surgical Guide.
The goal of this clinical trial is to evaluate the surgical accuracy and healing outcomes of endodontic surgery performed with the assistance of a 3D-printed static surgical guide in patients requiring apicoectomy.
- Conditions
- Periapical Periodontitis, Periradicular Lesion, Endodontic Treatment Failure, Postoperative Wound Healing
- Trial name
- NCT07734987
- Testing
- 3D-Printed Static Surgical Guide and Trephine Bur, Ultrasonic Retrograde Preparation and Bioceramic Retrograde Obturation
- Where
- Vietnam
- Volunteers
- 11 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Apical Periodontitis
Lesion Healing After Regenerative Endodontic Treatment
Endodontics involves various therapeutic interventions for diagnosing, preventing, and managing pulpal and periradicular pathologies.
- Trial name
- NCT06843850
- Testing
- regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Immature Teeth, Periapical Lesion
Three Techniques in Bioceramic Apexification for Necrotic Immature Incisors
The goal of this randomized clinical trial is to find the most effective Bioceramic-based apexification procedures in children with immature necrotic maxillary incisors.
- Trial name
- NCT06119477
- Testing
- Bioceramic Putty Apical Plugs, Single Cone Gutta-percha with Bioceramic Sealer, Combination of Bioceramic Putty and Sealer
- Where
- Syria
- Volunteers
- 45 people
- Sponsor
- Damascus University
Periapical Lesion
Guided Tissue Regeneration in Healing of Through and Through Periapical Lesion
Aim of this study is to evaluate the effect of i-PRF in the healing of through and through periapical lesion after periradicular surgery
- Trial name
- NCT04391725
- Testing
- Periapical surgery with guided tissue regeneration, Periapical surgery without anyguided tissue regeneration
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Apical Lesion
The Effect of Injectable Platelet Rich Fibrin on Apical Lesion Healing
In recent years, the use of autologously obtained blood products that stimulate cell proliferation, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), has become increasingly widespread.
- Trial name
- NCT07876427
- Testing
- i-PRF, root canal treatment and intracanal medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hande Has Elçi
Endodontic-Periodontal Lesions, Apical Periodontitis
The Effect of Different Intra-canal Medications on Healing of Endo-perio Cases.
Assessment of different intra-canal medications in endo-perio lesion regarding their healing potentiality and their effect on local cytokine levels.
- Trial name
- NCT07858396
- Testing
- Bio-ceramic, Calcium Hydroxide (CH), Chlorhexidine
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Periapical Lesions
Guided Tissue Regeneration in the Healing of Through and Through Lesions
Study Title: Effects of Guided Tissue Regeneration on the Healing of Through \& Through Periradicular Lesions - A Randomized Controlled Study Rationale: Through and through defects found to be difficult to heal without GTR…
- Trial name
- NCT03284736
- Testing
- Resorbable membrane, periapical surgery without membrane
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periapical Lesions
Platelet Rich Plasma in Healing of Through and Through Periradicular Lesions
Title : Evaluation of the efficacy of Platelet Rich Plasma (PRP) in healing of through and through lesions Rationale: Bone replacement analogues have been used in the healing after periapical surgery.
- Trial name
- NCT03430557
- Testing
- PRP, periapical surgery without PRP
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periapical Diseases, Endodontic Disease
Role of GTR on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication
The recovery of periapical defects linked to periodontal communication frequently yields less satisfactory results. Numerous studies and case reports have highlighted the notable success achieved through the application of guided…
- Trial name
- NCT06643663
- Testing
- Endodontic Micro-Surgery
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Apical Periodontitis
The Effect of Human Umbilical Cord Mesenchymal Stem Cells and Exosomes on the Healing of Postoperative Pain and Periapical Lesions in the Treatment of Apical Periodontitis: Randomized Controlled Clinical Study
The main purpose of this study is to evaluate the effect of Mesenchymal Stem Cells (MSCs) isolated from the umbilical cord and exosomes derived from these cells on the success of the treatment in the regenerative endodontic…
- Trial name
- NCT06764004
- Testing
- Stem Cell Product, Bleeding and clots
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University