Clinical trials: Partial-thickness Burn Wounds
Burns
The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns
The objective of the proposed study is to assess whether the application of flammacerium for 2 days is as good as, or even better than, the application of flammacerium for 10 days regarding woundhealing in partial thickness burns.
- Trial name
- NCT00156988
- Testing
- cerium nitrate-silver sulfadiazine (cerium-flamazine)
- Where
- Netherlands
- Sponsor
- Association of Dutch Burn Centres
Superficial Partial Thickness Burn, Skin Graft; Complications
Nitric Oxide Generating Gel Dressing in Patients With Superficial Partial Thickness Wounds
This is a study to assess the safety and efficacy of a nitric oxide (NOx) generating dressing on superficial partial thickness (SPT) wounds. Nitric oxide has a range of effects on the body including vasodilation and angiogenesis.
- Trial name
- ProNOx2 (NCT01983085)
- Testing
- NOx dressing, Standard of Care
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Edixomed Ltd
Burn
Use of Amnion on Partial Thickness Burns
To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.
- Trial name
- Amnion (NCT00674999)
- Testing
- Amnion, Polysporin/Bacitracin/Mycostatin
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Awbat Versus Biobrane in Partial Thickness Burns
To determine if AWBAT, used in treating partial-thickness burns, would provide better healing, pain control, control of infection, shorter length of hospital stay, lower costs, and improved scarring and long term recovery when…
- Trial name
- Awbat (NCT00847496)
- Testing
- AWBAT, Biobrane
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Skin Wound, Burns
StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects
Autografting is a surgical procedure to transplant healthy skin (donor skin) from another part of the participant's own body (donor site) to the burned part. Autografting is the usual treatment for DPT burns.
- Conditions
- Skin Wound, Burns, Trauma-related Wound
- Trial name
- StrataSTEPS (NCT05517902)
- Testing
- StrataGraft
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Burns
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This multicentre phase III clinical trial will target adults and adolescents of 12 years and older with severe burns to confirm the efficacy and functionality of denovoSkin™ in achieving wound closure and reducing scarring in…
- Trial name
- NCT06745557
- Testing
- denovoSkin(TM), STSG
- Where
- 19 sites in Belgium, France and 7 more
- Volunteers
- 70 people
- Sponsor
- CUTISS AG
Burns, Wound Healing
A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Approximately 55-65 subjects from 3-6 sites suffering from a burn injury covering 1-25% Total Body Surface Area (TBSA) will be evaluated providing they fulfill all inclusion and none of the exclusion criteria and have given a…
- Trial name
- NCT01636362
- Testing
- Mepitel Ag
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- Molnlycke Health Care AB
Burn
Epidermal Cells Delivery and Acute Burns
The aim of the study is to compare results obtained with epidermal cell spray and classic skin grafting for epidermal replacement in acute burns
- Trial name
- ENSEM (NCT00774033)
- Testing
- autologous epidermal cells harvesting kits, classic skin grafts
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burns Second Degree
Thermal Imaging and Pediatric Burns
The need to cover a burn with a skin graft is determined primarily by its depth. In fact only burns of the second deep degree or the third degree are likely to be grafted.
- Trial name
- FLIRPED (NCT03702972)
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wounds and Injuries, Burns
Treatment of Wounds With a New Adhesive Foam Dressing
This study will look at whether ELECT, a new adhesive foam dressing, can offer an alternative to traditional wound care methods. Patients will be treated with ELECT for 14 days.
- Trial name
- NCT02807584
- Testing
- ELECT
- Where
- South Africa
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Partial-thickness Burn
PermeaDerm® vs. Mepilex-Ag® in Promoting Healing of Partial-thickness Burn Wounds
The purpose of this study is to compare the effectiveness of the wound dressings currently used at our institution for partial-thickness burn wounds: PermeaDerm® (PermeaDerm, Inc., Carlsbad, California, USA) and silver…
- Trial name
- NCT03613870
- Testing
- PermeaDerm, Mepilex Ag
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns Degree Second, Pediatric
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO).
- Trial name
- CHITAG (NCT06987981)
- Testing
- Chitosan-based dressing, Silver-based dressing
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Miloš Potkonjak
Burn Injury, Soft Tissue Injury
Phase I Study for Autologous Dermal Substitutes and Dermo-epidermal Skin Substitutes for Treatment of Skin Defects
The purpose of this study is the evaluation of the safety of autologous tissue-engineered dermal substitutes "denovoDerm" (first arm) and dermo-epidermal skin substitutes "denovoSkin" (second arm) transplanted onto the wound bed…
- Conditions
- Burn Injury, Soft Tissue Injury, Skin Necrosis, Scars
- Trial name
- NCT02145130
- Testing
- denovoDerm, denovoSkin
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Surgical Wound, Trauma Wound
Randomized Controlled Trial to Investigate Clinical Outcomes and Associated Costs When PermeaDerm is Used as Temporary Dressing for Surgical Wounds
The goal of this study is to compare the cost and clinical outcomes for two temporary dressings (Allograft and PermeaDerm) used in patients that need a skin graft to heal their wound.
- Conditions
- Surgical Wound, Trauma Wound, Autografts, Partial-thickness Burn
- Trial name
- NCT06750809
- Testing
- PermeaDerm Biosynthetic Wound Matrix, Frozen Human Cadaveric Allograft (FHCA)
- Where
- 13 sites in United States
- Volunteers
- 40 people
- Sponsor
- Avita Medical
Wound Healing
Cell Suspension With Biologic Dressing for Burn Wounds
This study is a prospective, multicenter, real-world observational study. It aims to evaluate the effectiveness and safety of a combined therapy-autologous epidermal cell suspension followed by biological dressing (porcine…
- Trial name
- NCT07555418
- Testing
- Autologous Epidermal Cell Suspension
- Volunteers
- 386 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Skin Burn Degree Second
Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.
- Trial name
- NCT01790763
- Testing
- Keramatrix, Mepilex
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns, Ascorbic Acid Deficiency
Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death.
- Conditions
- Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second
- Trial name
- NCT05612867
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Arrowhead Regional Medical Center
Burn Wounds - Partial Thickness (2nd Degree)
Bacterial Control in Partial Thickness Burns Using Silver-containing Wound Dressings
This study is to compare the treatment with two different silver-containing wound dressings: aquacel AG hydrofiber versus acticoat burn dressing.
- Trial name
- NCT00343824
- Testing
- aquacel AG hydrofiber versus acticoat burn dressing
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Burn, Partial Thickness
Comparison of Collagenase With Antibiotic Ointment of Minor Partial Thickness Burns
By doing this study, researchers hope to learn if applying Santyl to the burn during the healing process affects the appearance of the resulting scar.
- Trial name
- NCT02673229
- Testing
- Collagenase Santyl, Bacitracin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Burn
Feasibility Study: Enzymatic Debridement in Patients With Partial Thickness Burns
Burns represent one of the most severe and dreaded traumas. Burned and traumatized tissue is known as eschar. The dead eschar, if not removed, often becomes heavily contaminated and is the source of local and/or systemic…
- Trial name
- NCT00898521
- Testing
- DGD
- Where
- 2 sites in India, Israel
- Volunteers
- 36 people
- Sponsor
- MediWound Ltd