Clinical trials: Overactive Bladder, open to volunteers
Urinary Incontinence, Daytime Wetting
The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.
The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI)…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urologic Diseases
- Trial name
- NCT07535619
- Where
- 4 sites in Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Overactive Bladder (OAB), Lower Urinary Tract Dysfunction
Parasacral TENS Project
The purpose of the project is to compare the efficacy of parasacral transcutaneous electric nerve stimulation (TENS) versus standard second-line therapy (oral anticholinergics) for pediatric patients with overactive bladder (OAB)…
- Trial name
- NCT07892417
- Testing
- Parasacral transcutaneous electric nerve stimulation (TENS), Oxybutynin
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Overactive Bladder (OAB)
Transcutaneous Tibial Nerve Stimulation Therapy in Children With Overactive Bladder
Overactive bladder (OAB) is a syndrome characterized by urinary urgency, often accompanied by frequency and nocturia, with or without urge incontinence, without urinary tract infection or other clear pathological changes.
- Trial name
- NCT06765629
- Testing
- Non-invasive Percutaneous Tibial Nerve Stimulation (TTNS) group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Overactive Bladder, Overactive Bladder Syndrome
Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children
The purpose of this study is to find out if overactive bladder (OAB) can be safely treated by stimulating a nerve near the ankle. This procedure is called percutaneous tibial nerve stimulation (PTNS).
- Trial name
- POSITRON-C (NCT06769854)
- Testing
- Urgent PC
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chi Dang Hornik
Urinary Incontinence in Children
Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)
The primary objective is to evaluate if (1) combination therapy of solifenacin and mirabegron in low doses is superior to monotherapy of solifenacin in high dose and if (2) combination therapy of mirabegron and solifenacin in low…
- Trial name
- NCT06551246
- Testing
- Solifenacin, Mirabegron
- Where
- 5 sites in Denmark
- Volunteers
- 236 people
- Sponsor
- University of Aarhus
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Urinary Bladder, Overactive, Overactive Bladder
Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet
The purpose of this clinical trial is to investigate whether adding high-dose vitamin D (2,400 IU daily) to standard medical treatment (solifenacin combined with behavioral therapy) is more effective than standard treatment alone…
- Conditions
- Urinary Bladder, Overactive, Overactive Bladder, Urinary Incontinence, Urge
- Trial name
- NCT06201013
- Testing
- urotherapy, Solifenacin Succinate, Vitamin D3
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Bladder Dysfunction
NESA Neuromodulation Versus Transcutaneous Posterior Tibial Stimulation
Introduction: Overactive bladder (OAB) is a common condition characterized by urinary urgency, frequency, and, in some cases, urge incontinence.
- Trial name
- NesaTibial (NCT07019597)
- Testing
- Non-invasive neuromodulation NESA(NNG), Non-invasive Neuromodulation Posterior Tibial (NTPG)
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Daniel David Álamo Arce
Spina Bifida
Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder Dysfunction
Malformation of the lumbosacral region (spina bifida) affects the innervation of the bladder in children. The usual evolution leads to a neurological bladder with small capacity, poor compliancy and overactivity, exposing to…
- Trial name
- POXIPEN (NCT07027020)
- Testing
- Oxybutynin Hydrochloride
- Where
- 19 sites in France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Overactive Bladder, Vitamin D Deficiency
The Role of Urinary RhoA, NGF, and BDNF Levels in Overactive Bladder and Vitamin D Deficiency
The primary aim of this study is to evaluate the role of three specific urinary proteins-RhoA, Nerve Growth Factor (NGF), and Brain-Derived Neurotrophic Factor (BDNF)-as potential biomarkers for the diagnosis and follow-up of…
- Trial name
- NCT07513363
- Testing
- Urotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tarik Emre Sener
Overactive Bladder (OAB), Transcutaneous Neurostimulation
Comparative Study of the Efficacy of Treatment of Idiopathic Overactive Bladder (OAB) in Children: Oxybutynine vs. Transcutaneous Neurostimulation
The absence of infectious, urological and neurological causes defines the idiopathic character of overactive bladder (OAB). Although a progressive approach starting with behavioural therapy (urotherapy) is recommended…
- Conditions
- Overactive Bladder (OAB), Transcutaneous Neurostimulation, Posterior Tibial Nerve Stimulation
- Trial name
- HAV-O-TENS (NCT07030803)
- Testing
- Oxybutynin, medical device Urostim
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Overactive Bladder Syndrome, Neuropathic Bladder
Oxybutynin for Post-surgical Bladder Pain and Urgency
Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.
- Trial name
- NCT03952299
- Testing
- Oxybutynin Transdermal Patch, Oral Oxybutynin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis