Clinical trials: Osteo Arthritis
Osteo Arthritis Knee and Hip, Artificial Intelligence (AI)
Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients
This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with…
- Conditions
- Osteo Arthritis Knee and Hip, Artificial Intelligence (AI), Acceptability, Accuracy
- Trial name
- PARTICIPATE (NCT07202286)
- Where
- Netherlands
- Volunteers
- 286 people
- Sponsor
- Canisius-Wilhelmina Hospital
Osteo Arthritis Knee, Surgery
Dynamic Congruence Total Knee Replacement vs Posterior-stabilized
This study compares and evaluates differences in movement analysis, patient-reported outcome between patients undergoing total knee arthroplasty with use of either Zimmer Biomet NexGen with posterior stabilization and Bioimplanti…
- Conditions
- Osteo Arthritis Knee, Surgery, Joint Diseases
- Trial name
- K-Mod (NCT04524312)
- Testing
- Total knee replacement, Biomechanics, NexGen Ps or Bioimplanti K-MOD implant
- Where
- Poland
- Volunteers
- 56 people
- Sponsor
- Medical University of Warsaw
Osteo Arthritis Knee
Tranexamic Acid in Total Knee Replacement
Multiple intravenous Tranexamic Acid doses can reduce postoperative blood loss and improve the functional outcome in total knee arthroplasty without tourniquet: a randomized controlled study.
- Trial name
- NCT03656445
- Testing
- Tranexamic Acid
- Volunteers
- 180 people
- Sponsor
- Democritus University of Thrace
Knee Pain Chronic, Osteo Arthritis Knee
Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.
This is an Individual Patient Expanded Access IND of autologous adipose derived Mesenchymal Stem Cells with the primary goal of treating 1 individual with bilateral knee pain who has exhausted all treatment options, his condition…
- Trial name
- NCT04604288
- Testing
- HB-adMSC
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Knee Injuries and Disorders, Osteo Arthritis Knee
RELIABILITY AND VALIDITY OF THE DT BALANCE TEST IN PATIENTS WITH TKA
The ability to perform a cognitive task while walking simultaneously is essential in real daily life. However, the psychometric properties of dual-task walking tests have not been well established in patients undergoing total…
- Trial name
- DT TKA (NCT06108466)
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Dokuz Eylul University
Osteo Arthritis Knee
The Use of Bone Growth Stimulators for Osteoarthritis of the Knee.
The hypothesis of this study is that since osteoarthritis of the knee is primarily a bone disease where the joint changes are secondary, and bone growth stimulators function to decrease intraosseous venous congestion and remodel…
- Trial name
- NCT03476382
- Testing
- Ultrasound Bone Growth Stimulator
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Coastal Carolinas Integrated Medicine
Rotator Cuff Tears, Osteo Arthritis Shoulders
Comparison Of A Novel Sling With A Traditional Abduction Sling After Shoulder Surgery
The objective of this study is to determine if the novel shoulder sling has higher patient satisfaction compared to a traditional, abduction sling with at least equivalent postoperative outcomes after arthroscopic rotator cuff…
- Trial name
- NCT05274737
- Testing
- Novel sling, Traditional abduction sling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Orthopedic Institute, Sioux Falls, SD
Osteoarthritis of the Hand
Compassionate Use of Pennsaid Topical Lotion (Diclofenac) in Osteo or Rheumatoid Arthritis
This was a compassionate use, open treatment safety study of Pennsaid topical lotion (diclofenac) for osteo or rheumatoid arthritis.
- Trial name
- NCT01579890
- Testing
- Diclofenac
- Sponsor
- Mallinckrodt
Osteo Arthritis Knee, Hip Osteoarthritis
Adapting REhabilitation Delivery for Maximum Impact at Home
Hip and knee osteoarthritis (OA) is a burden of disability in adults, with many seeking total joint arthroplasty (TJA) to reduce their symptoms.
- Conditions
- Osteo Arthritis Knee, Hip Osteoarthritis, Knee Osteoarthritis, Osteoarthritis
- Trial name
- ReDI@Home (NCT05164575)
- Testing
- progressive resistance exercise, self-management strategies
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- University of Alberta
Osteo Arthritis Knee
Arthroscopic Evaluation of Cartilage Regeneration After Opening-wedge High Tibial Osteotomy
Osteoarthritis of the knee is a common problem causing significant knee pain and disability. Medial compartment osteoarthritis is predisposed to by varus deformity of the knee.
- Trial name
- NCT04541342
- Testing
- initial arthroscopy with medial opening-wedge high tibial osteotomy fixed by a plate system then second look arthroscopy with plate removal
- Where
- 2 sites in Egypt
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Assiut University
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Osteo Arthritis of the Knee, Rhematoid Arthritis
Rehabilitation Approaches Used in Total Knee Replacement
In this study, we will investigate the rehabilitation approaches commonly used by physiotherapists in Pakistan following total knee replacement.
- Trial name
- NCT07375082
- Testing
- Questionnaire
- Where
- Pakistan
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Bahria University
Osteo Arthritis Knee, Arthroplasty, Replacement, Knee
Sharp Dissection Versus Monopolar Electrocautery in Primary Total Knee Arthroplasty Performed Under Tourniquet
This study compares the use of sharp dissection with diathermy for the approach to a total knee replacement. Half of the patients will be randomly assigned each intervention.
- Trial name
- NCT03559478
- Testing
- Sharp dissection with scalpel plus electrocautery to vessels, Electrocautery for all dissection
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Infirmary of Edinburgh
Osteo Arthritis Knee, Total Knee Arthroplasty
Comparing Surgical and Economical Parameters of Total Knee Replacement.
Randomized study comparing surgical and economic parameter of Total Knee Arthroplasty performed using two different specific surgical techniques.
- Trial name
- NCT03427047
- Testing
- MyKnee with single use Efficiency Instrument, Stryker Navigational with conventional metal instruments
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Osteo Arthritis Knee
Post-op Ketamine Study
The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption.
- Trial name
- NCT03865550
- Testing
- Isotonic saline, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rothman Institute Orthopaedics
Osteo Arthritis Knee
The Effect of Semiconductor Knee Sleeves on Pain in Osteoarthritis of the Knee.
To assess the benefits of using semiconductor (germanium and carbon) woven knee sleeves products in patients with osteoarthritis of the knee.
- Trial name
- NCT05255835
- Testing
- Semiconductor Knee Sleeves
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Herlev and Gentofte Hospital
Osteo Arthritis of the Knee, Genu Varum
Kinematic vs Mechanical Alignment in High Tibial Osteotomy
To compare between kinematic and mechanichal alignment after High Tibial Osteotomy (clinically and radiologically)
- Trial name
- NCT07551089
- Testing
- high tibial osteotomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Osteo Arthritis Knee
Evaluation of Standard and Robot Assisted Total Knee Arthroplasty with a Bicrucatie Retaining Prosthesis
The first study goal is to compare the outcomes between Posterior Stabilized and Bicruciate Retaining TKA. Additionally, the second goal is to evaluate the effect of robot assisted surgery in both Posterior Stabilized and…
- Trial name
- NCT04334304
- Testing
- Total Knee Prosthesis - type Bicruciate retaining, Robot-assisted Total Knee Arthroplasty, Total Knee Prosthesis - type Posterior Stabilized
- Where
- Belgium
- Volunteers
- 47 people
- Sponsor
- University Hospital, Ghent
Osteo Arthritis, Osteoporosis
Determining the Feasibility of Implementing a Combined Cognitive and Exercise Training Program for Older Adults in a Community Setting.
The overarching aim of this project is to implement and evaluate a proven cognitive training regimen in combination with a community exercise program among older adults who attend wellness exercise programs at the YMCA.
- Conditions
- Osteo Arthritis, Osteoporosis, Joint Replacement, Fibromyalgia
- Trial name
- NCT04515758
- Testing
- Exercise and Cognitive Training, Exercise Training Only
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of Waterloo
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
Gait Rehabilitation to Treat FastOA
The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee
- Trial name
- NCT05848622
- Testing
- Real-time gait biofeedback
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Carolina, Chapel Hill