Clinical trials: Orthopaedic Surgery
Polydactyly Toe, Thumb Hypoplasia
Clonidine for Tourniquet-related Pain in Children
This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of…
- Conditions
- Polydactyly Toe, Thumb Hypoplasia, Trigger Finger, Polydactyly; Fingers
- Trial name
- CLOTCH (NCT04564430)
- Testing
- Catapresan, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Inadequate or Impaired Breathing Pattern or Ventilation
Supreme LMA and Proseal LMA in Prone Anesthetized Patient
There is no significant difference about success rate of two devices.
- Trial name
- SPLMA (NCT01814306)
- Testing
- Supreme LMA, Proseal LMA
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Tendon Disorder
A Musculoskeletal Ultrasound Course for Orthopedic Surgery Residents
A group of orthopedic surgery residents underwent a structured online and practical musculoskeletal ultrasound course. Their proficiency on a written and practical exam, as well as frequency and comfort when using was recorded…
- Trial name
- NCT04204369
- Testing
- Ultrasound education curriculum
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Anemia
Non-invasive Identification of Preoperative Anaemia
Approximately 20% of patients undergoing elective orthopaedic surgery are anaemic. When not identified and treated before surgery, this can lead to requiring blood transfusions, which brings additional expenses, time and…
- Trial name
- NIPPA (NCT04247178)
- Where
- United Kingdom
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Puncture, Surgical Gloves
The Effect of Using Double Gloves on Perforation in Orthopedic Surgery
Aim: This study aimed to investigate the effect of using double gloves on perforation in orthopedic surgery. Materials and Method: The randomized controlled experimental study was conducted between 30.11.2021 and 31.03.2022 in…
- Conditions
- Puncture, Surgical Gloves, Orthopedic Disorder
- Trial name
- NCT05928663
- Testing
- double surgical gloves, single surgical gloves
- Where
- Turkey (Türkiye)
- Volunteers
- 1,170 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Axillary Brachial Plexus Block
The Efficacy of Intravenous Dexamethasone on the Duration of Analgesia of Ultrasound Guided Axillary Brachial Plexus Block in Pediatric Patients Undergoing Below Elbow Orthopaedic Surgeries
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage , inadequate intraoperative pain assessment and management.
- Trial name
- NCT05466500
- Testing
- Ultrasound guided axillary block with intravenous dexamethasone, Ultrasound guided axillary block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Other Conditions That May Be A Focus of Clinical Attention
Effectiveness of Buddhist Intergrated Group Intervention on Minefulness in Adolescents
The pupose of the study is to determine the effectiveness of the Buddhist integrated group intervention improve the mindfulness in adolescents by a randomized controlled trial.The study divede the adolescents in two groups group…
- Trial name
- NCT01605604
- Testing
- buddhist mind fullness
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Orthopedic Procedures, Methicillin-resistant Staphylococcus Aureus
Treatment of Patients Colonized With Methicillin-Resistant Staphylococcus Aureus Prior to Bone and Joint Surgery
The investigators anticipate that utilization of retapamulin preoperatively will eliminate MRSA colonization among patients who are colonized in their nares.
- Trial name
- TOPS-MRSA (NCT00903279)
- Testing
- Altabax (retapamulin)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bay Pines VA Healthcare System
Scoliosis
The Idiopathic Scoliosis and Its Treatment (Orthopaedic and Surgery): Effect of the Severity, the Orthosis and the Arthrodesis on the Gait
The purposes of this study were as follows: 1) to compare locomotion parameters (kinematic, EMG, mechanical work and energy cost changes during walking in able-bodied subjects and AIS patients,2) to evaluate the effects of the…
- Trial name
- scoliosis (NCT00842218)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Hip Arthroplasty
Stem Cells Predicting Orthopedic Outcomes
This is a pilot study to provide preliminary data of the association between bone mineral denity adjacent to acetabular implants, as measured by quanitative computed tomography (QCT), at least 2 years post Total Hip Arthoplasty…
- Trial name
- NCT01366911
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
This study aims to analyze the efficacy of intravenous tranexamic acid (TXA) in patients undergoing total hip arthroplasty (THA).
- Conditions
- Blood Loss, Surgical, Tranexamic Acid Adverse Reaction, Hip Replacement
- Trial name
- NCT03019198
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Brazil
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Virtual Reality
Virtual Reality for Reducing Anxiety in Pediatric Orthopedic Surgery
This study, titled "R.A.G.A.Z.: Virtual Reality for Reducing Anxiety and Pain in Pediatric Orthopedic Surgery," aims to see if using virtual reality (VR) can help children feel less anxious and experience less pain during minor…
- Trial name
- RAGAZ (NCT06604364)
- Testing
- hypno VR
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Trigger Thumb
Study of Open and Percutaneous Release of Acquired Trigger Thumb
Trigger finger, also known as trigger digit or stenosing tenovaginitis, is caused by a size mismatch between the flexor tendon and the A1 pulley, which is generally characterized by pain, swelling, the limitation of finger range…
- Trial name
- NCT03679793
- Testing
- Open Release Group, Percutaneous Release Group
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Orthopedic Disorder
Improve the Quality of Care in Patients With Orthopaedic Disorders
The main objective of the investigators is to improve the quality of care in patients with orthopedic disorders followed in St Luc hospital (Brussels Belgium).
- Trial name
- QualOrtho (NCT02355301)
- Testing
- orthopedic
- Where
- Belgium
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Hand Surgery, Orthopedic Surgery
Evaluating Clinical Outcomes for Determining the Optimal Delay to Skin Incision Under WALANT
Further studies are needed to establish the effects of WALANT in performing most common hand surgeries, in relation to its clinical outcomes and intraoperative blood loss.
- Trial name
- WALANT (NCT04491656)
- Testing
- WALANT Technique
- Where
- Philippines
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- East Avenue Medical Center, Philippines
Pain, Genetic Change
COMT and OPRM1 Polymorphisms and Their Effect on Post-Operative Pain in Children
The goal of this observational study is to investigate whether the A118G single-nucleotide polymorphism (SNP) in the mu-opioid receptor1(OPRM1) and Catechol-O-methyltransferase (COMT) SNPs influence postoperative pain scores in…
- Conditions
- Pain, Genetic Change, Children, Only
- Trial name
- NCT06777875
- Where
- Lebanon
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Surgical Education, Virtual Reality
Virtual Reality in Orthopaedic Surgical Education: A Randomized Controlled Trial
Immersive virtual reality (IVR) surgical simulators are increasingly being used for learner education. The aim of this randomized controlled trial is to compare the efficacy of IVR to hands-on orthopaedic workshop sessions (such…
- Conditions
- Surgical Education, Virtual Reality, Orthopaedic Training
- Trial name
- VR-ORS (NCT05830786)
- Testing
- Immersive virtual reality (IVR), Traditional hands on orthopaedic workshop group
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto