Clinical trials: Opioid Use After Surgery
Ureteropelvic Junction Obstruction, Hypospadias
Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children
The goal of this clinical trial is to determine whether giving oxybutynin before urologic reconstruction surgery reduces the amount of opioid pain medication needed in children.
- Trial name
- NCT07911137
- Testing
- Oxybutynin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary
Postoperative Pain
Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion
Blinded study using oral gabapentin in load pre-operative (15mg/kg) and maintenance 5mg/kg three times a day (TID) for 5 days or discharge, Patient Controlled Analgesia (PCA) morphine and placebo group with similar pills, also…
- Trial name
- NCT00726999
- Testing
- Gabapentin, Morphine
- Volunteers
- 63 people
- Sponsor
- Medical College of Wisconsin
Adenotonsillectomy, Post-operative Analgesia
Non-opioids for Analgesia After Adenotonsillectomy in Children
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT03618823
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- David Chi, MD
Pediatric ALL, Cancer
A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Naïve Undergoing Surgery to Reduce Postoperative Opioid Use (GAMING-ON Study)
To learn if playing an augmented reality game called SpellBound can reduce pain and the need for opioids in young patients scheduled for surgery.
- Trial name
- NCT05466994
- Testing
- IPAD, Augmented Reality
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative, Opioid Use
Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction
Research question: Does an opioid limiting pain management counseling and education program result in decreased opioid consumption and improved pain control compared to traditional pain management programs after anterior cruciate…
- Trial name
- CARE (NCT04885231)
- Testing
- Perioperative Pain Management Education and Counseling
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Maryland, Baltimore
Surgical Procedure, Unspecified, Orthopedic Disorder
Opioid Consumption After Knee Arthroscopy
This is a prospective, randomized trial of patients undergoing outpatient knee arthroscopy surgery and receiving a peripheral nerve block.
- Trial name
- NCT03299920
- Testing
- Standardized instructions, Conventional instructions
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Giorgio Veneziano
Postoperative Pain, Opioid Use
Sex Hormones, Postoperative Pain and Opioid Use
Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use. Aim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are mediated by immune factors
- Trial name
- SPO (NCT06023225)
- Testing
- Pain, Opioid use
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Washington University School of Medicine
Cancer
A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Tolerant Users Undergoing Surgery to Reduce Post-operative Opioid Use
Tto learn if playing an augmented reality game called SpellBound can reduce pain and the need for opioids in young patients following surgery.
- Trial name
- NCT05589857
- Testing
- IPAD, Augmented Reality
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Adolescent Idiopathic Scoliosis (AIS)
Hypnosis for Pain and Nausea Reduction in Scoliosis Surgery: An Interventional Study
This study evaluates whether preoperative hypnosis can reduce postoperative pain, nausea, and opioid use in adolescents undergoing scoliosis surgery. Participants aged 12-18 years will receive hypnosis training before surgery.
- Trial name
- HYP-SCOL (NCT07854951)
- Testing
- Hypnosis
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Constipation
Methylnaltrexone Use for Opioid-induced Postoperative Constipation
The purpose of this study is to determine whether the routine use of methylnaltrexone in the post-operative pediatric spinal fusion patient will decrease the incidence of constipation.
- Trial name
- NCT01773096
- Testing
- Methylnaltrexone, Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shriners Hospitals for Children
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy
ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy
This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic…
- Trial name
- ESP TAP (NCT07661693)
- Testing
- Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziantep City Hospital
Pain, Postoperative
The Effect of Femoral Nerve Block on Opioid Requirements After Surgery for a Femur Fracture in Children
This study evaluates the effect of a femoral nerve block on opioid requirements following femoral fracture fixation with flexible nails in the paediatric population. This is a double blind, prospective randomized clinical trial.
- Trial name
- NCT00175591
- Testing
- Administration of a femoral nerve block (bupivacaine HCL)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of British Columbia
Tonsillitis, Sleep Disordered Breathing
Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery
Opioids are an important component of post-operative pain management among children, but are often prescribed in excess and rarely disposed of appropriately.
- Conditions
- Tonsillitis, Sleep Disordered Breathing, Hernia, Hydrocele
- Trial name
- NCT03575377
- Testing
- Disposal Aid
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Nationwide Children's Hospital
Surgery, Opioid Use
Increasing Implementation of Post-Operative Opioid Prescribing Guidelines
The objective of this research study is to evaluate the effect of a quality improvement initiative carried out by a health system opioid stewardship task force aiming to increase clinician post-operative prescribing adherence…
- Conditions
- Surgery, Opioid Use, Opioid Misuse, Prescription Opioid Misuse
- Trial name
- NCT05358522
- Testing
- Opioid Prescribing Report Cards
- Where
- United States
- Volunteers
- 26,562 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Radiculopathy, Central Spinal Stenosis
The Efficacy of Continuous Cold-Therapy on Postoperative Pain and Narcotics Use Following Spinal Fusion
Patient outcomes and satisfaction are an ever-increasing priority in surgical specialties. Cryotherapy has been utilized following spine surgery as an adjunct therapy to reduce postoperative inflammation and improve patient…
- Conditions
- Radiculopathy, Central Spinal Stenosis, Foraminal Stenosis, Herniated Nucleus Pulposus
- Trial name
- NCT03640338
- Testing
- Cold-Therapy System
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Opioid Use, Pain, Postoperative
Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to usual post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation program…
- Conditions
- Opioid Use, Pain, Postoperative, SLAP Lesion, Bankart Lesion
- Trial name
- NCT03525275
- Testing
- Battlefield Acupuncture, Post-surgical shoulder protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Keller Army Community Hospital
Pain, Postoperative, Medication Adherence
Scenario Tailored Opioid Messaging Program (STOMP) to Improve Risk Understanding in Young Adults
Legitimate prescription opioid use during adolescence has been associated with later prescription opioid misuse and substance use disorder symptoms during adulthood.
- Conditions
- Pain, Postoperative, Medication Adherence, Opioid Use, Knowledge, Attitudes, Practice
- Trial name
- STOMPYA (NCT03863353)
- Testing
- Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 503 people
- Sponsor
- University of Michigan
Postoperative Pain, Opioid Use
Erector Spinea Plane Block in Pediatric Hip Surgery
This prospective randomized controlled double-blind study will be carried out to evaluate the effect of ultrasound-guided erector spinae plane block on the postoperative analgesia in children after hip surgeries, the total…
- Trial name
- NCT04374396
- Testing
- Real ultrasound-guided single shot erector spinae plane block (ESP B)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Opioid Use Disorder, Pain, Chronic
Adolescent Outcomes of Post-operative Opioid EXposure
The goal of this observational study is to examine the factors associated with the transition from medical exposure to opioids with "signposts" of future opioid use disorder among adolescent surgical patients.
- Trial name
- APEX (NCT06350409)
- Where
- 5 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Sharon Levy