Clinical trials: Opioid Consumption, Postoperative
Ureteropelvic Junction Obstruction, Hypospadias
Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children
The goal of this clinical trial is to determine whether giving oxybutynin before urologic reconstruction surgery reduces the amount of opioid pain medication needed in children.
- Trial name
- NCT07911137
- Testing
- Oxybutynin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary
Postoperative Pain, Opioid Consumption
Comparison of TAP Block and Umbilical Paramedian Linea Semilunaris Block in Pediatric Laparoscopic Surgery
The aim of this prospective randomized controlled trial is to compare the postoperative analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block and umbilical paramedian linea semilunaris block in pediatric…
- Trial name
- NCT07801794
- Testing
- Ultrasound-Guided Transversus Abdominis Plane Block, Ultrasound-Guided Linea Semilunaris Block
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Breast Cancer Surgery
Effect of Intravenous S-ketamine on Opioid Consumption
Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study.
- Trial name
- NCT05060068
- Testing
- S-ketamine (low dose), S-ketamine (high dose)
- Where
- China
- Volunteers
- 345 people
- Sponsor
- The Second Hospital of Anhui Medical University
Pain, Postoperative, Opioid Use
Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction
Research question: Does an opioid limiting pain management counseling and education program result in decreased opioid consumption and improved pain control compared to traditional pain management programs after anterior cruciate…
- Trial name
- CARE (NCT04885231)
- Testing
- Perioperative Pain Management Education and Counseling
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Maryland, Baltimore
Surgical Procedure, Unspecified, Orthopedic Disorder
Opioid Consumption After Knee Arthroscopy
This is a prospective, randomized trial of patients undergoing outpatient knee arthroscopy surgery and receiving a peripheral nerve block.
- Trial name
- NCT03299920
- Testing
- Standardized instructions, Conventional instructions
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Giorgio Veneziano
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Post Operative Analgesia, Tonsillectomy With or Without Adenoidectomy
Preoperative High-Dose Oral Paracetamol for Postoperative Analgesia in Children Undergoing Tonsillectomy"
This randomized clinical trial compares two different preoperative doses of oral paracetamol (acetaminophen) in children undergoing elective tonsillectomy.
- Trial name
- NCT07463482
- Testing
- Paracetamol (acetaminophen)
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Thammasat University
Erector Spinae Block, Enhanced Recovery After Surgery (ERAS) Protocol
Erector Spinae Block in Reducing Peri-operative Opioid Consumption in Total Abdominal Hystrectomy
Hystrectomy is a surgical procedure that involves removal of uterus from the body of patient using a lower abdominal incision. This is an extremely painful procedure which causes discomfort and greatly increases opioids…
- Conditions
- Erector Spinae Block, Enhanced Recovery After Surgery (ERAS) Protocol, Opioid
- Trial name
- NCT07178262
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kulsoom International Hospital
Postoperative Pain, Thoracic Surgery Lung
Analgesic Efficacy and Hemodynamic Stability of Ultrasound-guided Thoracic Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Pediatric Thoracic Surgery: a Randomized Controlled Trial.
Thoracic surgery in children is considered a highly invasive procedure that significantly affects respiratory mechanics and cardiovascular function, resulting in substantial physiological disturbances during the perioperative…
- Conditions
- Postoperative Pain, Thoracic Surgery Lung, Thoracotomy Analgesia, Regional Anesthesia
- Trial name
- NCT07602179
- Testing
- Thoracic erector spinae plane block (ESPB), Thoracic epidural analgesia (TEA)
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Tooth Extractions
Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery
Wisdom teeth removal under general anaesthesia is usually suitable for ambulatory surgery. The choice of opioid in dental day surgery is based on the need for a rapid and full recovery, as well as less morphine administration.
- Trial name
- SUF-REM-DDS (NCT01139671)
- Testing
- Remifentanil
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Adolescent Idiopathic Scoliosis (AIS)
Intravenous Dexamethasone for ESP Block Analgesia in Children Undergoing Idiopathic Scoliosis Surgery
This randomized, double-blind, placebo-controlled study will evaluate the effect of intravenous dexamethasone on postoperative analgesia in children and adolescents undergoing surgery for idiopathic scoliosis with bilateral…
- Trial name
- NCT07890220
- Testing
- Dexamethasone (0.1 mg/kg), Dexamethasone (0.2 mg/kg)
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Nerve Block/Methods
Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients.
The goal of this clinical trial is to determine which regional block provides superior analgesia in pediatric patients undergoing thoracic surgery.
- Trial name
- NCT07796399
- Testing
- Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Postoperative Pain, Opioid Use
Erector Spinea Plane Block in Pediatric Hip Surgery
This prospective randomized controlled double-blind study will be carried out to evaluate the effect of ultrasound-guided erector spinae plane block on the postoperative analgesia in children after hip surgeries, the total…
- Trial name
- NCT04374396
- Testing
- Real ultrasound-guided single shot erector spinae plane block (ESP B)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Scoliosis Idiopathic, Pain, Postoperative
Virtual Reality After Pediatric Scoliosis Surgery
The purpose of this study is to evaluate the use of virtual reality after scoliosis surgery in pediatric patients.
- Trial name
- VRAS-PS (NCT04584970)
- Testing
- Applied VR, Apple iPad
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Carolina, Chapel Hill
Pediatric Anesthesia, Emergence Delirium, Anesthesia
Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening
This prospective, randomized, single-blind, two-arm parallel-group clinical trial evaluates whether EEG-guided sevoflurane titration affects intraoperative opioid consumption and emergence quality in children undergoing painful…
- Conditions
- Pediatric Anesthesia, Emergence Delirium, Anesthesia, Postoperative Pain, Tonsillectomy
- Trial name
- NCT07714785
- Testing
- EEG-guided, Standard
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Pain, Postoperative
Ultrasound Guided Pectoral Nerve I and II Blocks in Multimodal Analgesia for Breast Surgery
The primary objective of this study is to access the effect of Pectoral nerve I and II blocks in breast surgery as measured by consumption of postoperative morphine or its equivalent.
- Trial name
- NCT02672813
- Testing
- Pectoral nerve I and II block
- Where
- Nepal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
IV Lidocaine in Pediatric AIS
This study addresses the focus areas of Post-Operative Pain Management. We propose a randomized, triple-blind, placebo-controlled trial to investigate the efficacy of a systemic infusion of intravenous lidocaine as a non-opioid…
- Trial name
- PEDS LIDO (NCT03893318)
- Testing
- IV lidocaine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Pain Management, Postoperative Pain
Effects of S-ketamine on Perioperative Opioid Consumption
This study is a triple-blind randomized controlled trial conducted at a tertiary care hospital in Brussels. It investigates whether a single dose of S-ketamine can reduce opioid (morphine) consumption in the first 24 hours after…
- Conditions
- Pain Management, Postoperative Pain, Opioid Consumption, Postoperative, Opioid Analgesia
- Trial name
- NCT07528651
- Testing
- Esketamine at low dose, Saline (0.9% NaCl)
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Postoperative Pain, Acute, Opioid Use
Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair
The purpose of this study is to determine if patients age 15 to 30 years old being treated for shoulder labrum repair and SLAP lesions have significant differences in pain levels postoperatively when treated with a combination…
- Conditions
- Postoperative Pain, Acute, Opioid Use, Labral Tear, Glenoid
- Trial name
- NCT05974423
- Testing
- Tylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cooper Norcross Health
Postoperative Pain
Pudendal vs Caudal Block for Pediatric Penile Surgery
The study will compare recovery profile in children receiving pudendal blocks vs caudal analgesia for ambulatory circumcision or hypospadias repair in children between 6 months and 2 years.
- Trial name
- NCT04840654
- Testing
- Caudal Block, Pudendal Block
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago