Clinical trials: Obesity Associated Disorder
Physical Inactivity, Obesity
Factors Associated With Physical Inactivity Among Adolescents
Despite the acknowledgment that physical activity is important for health, there are still few population-based or school-based studies that uses the current physical activity guidelines for adolescents.
- Conditions
- Physical Inactivity, Obesity, Overweight
- Trial name
- FAPIA (NCT01137227)
- Where
- Brazil
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Breast Cancer
Diet and Exercise or Normal Care in Overweight or Obese Women Who Have Undergone Treatment for Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Studying diet and exercise interventions in overweight and obese patients with breast cancer may help doctors learn more about how to help patients lose weight and change their body composition.
- Trial name
- NCT00689975
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Sheffield Hallam University
Eye Diseases, Obesity Associated Disorder
Ophthalmologic Evaluation of Patients With Obesity and Metabolic Syndrome Before and After Bariatric Surgery
The aim of this study was to investigate the pathogenic role of obesity on blinding eye diseases in a population of severely obese patients with no history of eye diseases, and to verify whether weight loss induced by bariatric…
- Trial name
- NCT04926714
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- XiaoYong Liu
Obesity Associated With Defects in Leptin-melanocortin Pathway
Open-Label Extension Study of Setmelanotide
This is an open-label extension study designed to evaluate the long-term safety and tolerability of continued setmelanotide treatment in male and female patients ≥2 years of age who have completed or transitioned from a previous…
- Trial name
- NCT06596135
- Testing
- Setmelanotide
- Where
- 13 sites in United States
- Volunteers
- 28 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity
25-Hydroxyvitamin D Levels Are Negatively Associated With Platelets Number in a Cohort of Overweight and Obese Subjects
This study was aimed to investigate the associations between platelet number and 25(OH)D serum concentration in apparently healthy but overweight/obese subjects.
- Trial name
- NCT04133441
- Where
- Italy
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Obesity, Cardiovascular Risk
School Based Health Promotion Program in Secondary Schools
The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.
- Trial name
- JuvenTUM 3 (NCT00988754)
- Testing
- School children and adolescents as health experts
- Where
- Germany
- Volunteers
- 595 people
- Sponsor
- Technical University of Munich
Metabolic Dysfunction-Associated Steatotic Liver Disease, Childhood Obesity
Lifestyle Habits and Metabolic Dysfunction-Associated Steatotic Liver Disease in Youth
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease in children and adolescents.
- Trial name
- LIFE4MASLD (NCT07095010)
- Where
- Greece
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Obesity, Cardiovascular Risk
Long-term Effects of Lifestyle Intervention in Obesity and Genetic Influence
The purpose of the study is to determine the genetic influence on short-, middle- and longterm effects of an inpatient lifestyle therapy program in overweight and obese children and adolescents.
- Trial name
- LOGIC (NCT01067157)
- Testing
- LOGIC
- Where
- Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Obesity, Hyperandrogenemia
Etiological Factors of Obesity-Associated Hyperandrogenemia in Peripubertal Girls
The purpose of this study is to learn if obese pre- and early pubertal girls with hyperandrogenemia (HA) are more insulin resistant (i.e., have lower insulin-stimulated glucose disposal) compared to obese peripubertal girls…
- Conditions
- Obesity, Hyperandrogenemia, Polycystic Ovary Syndrome
- Trial name
- CRM002 (NCT00928759)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity, Adolescent, Eating, Healthy
Prevention of Eating Habits Associated With Obesity
This study evaluates the effectiveness of a Wise Intervention based on a values alignment approach to improve obesity-related eating habits in Spanish adolescents.
- Trial name
- NCT05865444
- Testing
- Values alignment wise intervention, Educational traditional intervention
- Where
- Spain
- Volunteers
- 591 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Childhood Onset Obesity
GENYAL Study to Childhood Obesity Prevention
Obesity is a multifactorial, complex, chronic disease of special concern. It is originated as an interaction between genetic predisposition and environmental factors.
- Trial name
- NCT03419520
- Testing
- Nutritional counseling
- Where
- Spain
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Anorexia Nervosa Restricting Type, Anorexia Nervosa (DSM-IV Revised Criteria)
Biomarkers in EV Associated With Marrow Adiposity in Anorexia
The aim of this observational study is to identify biomarkers in extracellular vesicles associated with medullary adiposity occurring in patients with anorexia nervosa.
- Trial name
- VE_BMAT_AN (NCT06712485)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Hypertriglyceridemia, Obesity
Setmelanotide in a Single Patient With Partial Lipodystrophy
The objective of this single patient study is to assess the safety and efficacy of setmelanotide as a treatment of severe metabolic abnormalities resulting from LD, especially refractory hypertriglyceridemia leading to recurrent…
- Trial name
- NCT03262610
- Testing
- Setmelanotide
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Type 1 Diabetes, Obesity
Prevalence of Overweight and Obesity in Adult Patients Suffering From Type 1 Diabetes
A registry of individuals with type 1 diabetes that visited the Department of Endocrinology of the University Hospitals of Leuven is established.
- Trial name
- POOT1 (NCT05713448)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 100,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteogenesis Imperfecta, Osteoporosis
REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)
This study evaluates bone mineral density (BMD) in pediatric patients aged 5-18 years with conditions negatively affecting bone health, using REMS (Radiofrequency Echographic Multi Spectrometry), a non-invasive and radiation-free…
- Conditions
- Osteogenesis Imperfecta, Osteoporosis, Hypogonadisms, Neoplasia
- Trial name
- NCT07412782
- Testing
- REMS
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Meyer Children's Hospital IRCCS
Prader-Willi Syndrome
Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess the utility of Guanfacine Extended Release (GXR) in the management of patients with Prader Willi Syndrome (PWS) who have significant aggression or self-injury.
- Trial name
- NCT04066088
- Testing
- Guanfacine extended release (GXR)
- Where
- United States
- Sponsor
- NYU Langone Health
Binge Eating Disorder
An Open-Label Trial of Memantine in the Treatment of Binge Eating Disorder
We hypothesize that memantine may be a safe and effective treatment for moderate to severe binge eating disorder associated with obesity.
- Trial name
- NCT00330655
- Testing
- memantine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mclean Hospital
Eating Disorders, Binge-Eating Disorder
The Effects of Nutritional Intervention in Participants With Eating Disorders.
The goal of this clinical trial is to evaluate the effects of nutritional intervention in eating disorders. Participants underwent an intervention without a control group over 8 weeks.
- Conditions
- Eating Disorders, Binge-Eating Disorder, Binge Eating Disorder Associated With Obesity, Eating Behavior
- Trial name
- NCT06230107
- Testing
- Mindful Eating
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- Sao Jose do Rio Preto Medical School
Obesity, Diabetes
Abu Dhabi Diabetes and Obesity Study
A cross-sectional study investigating the aetiology, mechanisms and associated complications contributing to obesity and diabetes within the UAE population.
- Trial name
- NCT01843959
- Where
- United Arab Emirates
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre