Clinical trials: Non-Diabetic
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
The aim of this study is to evaluate the chance of non-healing diabetic foot ulcers repair by improving the condition of lack of oxygen or hypoxia in the wound area caused by diabetes using methylene blue along with the use of…
- Trial name
- NCT05850611
- Testing
- Methylene Blue, Milk (control), Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Type 1 Diabetes Mellitus With Diabetic Nephropathy
Validation of Biomarkers of Diabetic Nephropathy in Type I Diabetic Children
About 30 to 40% of patients suffering from type I diabetes are at risk of developing a diabetic nephropathy (DN) leading more or less rapidly to an end-stage renal disease.
- Trial name
- peeDIAB2 (NCT02164279)
- Testing
- Urinary sample collection
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Toulouse
Healthy Subjects Without Type 1 Diabetes
Continuous Glucose Sensor Profiles in Non-Diabetic Subjects
The Juvenile Diabetes Research Foundation (JDRF) Glucose Sensor Study group is carrying out a large, randomized clinical trial to assess the efficacy, safety and cost-effectiveness of use of real-time continuous glucose monitors…
- Trial name
- NCT00717977
- Testing
- Continuous glucose monitor
- Where
- 10 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Jaeb Center for Health Research
Cardiovascular Diseases, Diabetes Mellitus, Non-insulin Dependent
Dyslipidemia and Risk of Cardiovascular Disease in Diabetic Men and Women
To determine the role of dyslipidemia, markers of endothelial dysfunction genetic susceptibility, and dietary fat intake on the development of cardiovascular disease (CVD) complications in Type II diabetes mellitus.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Non-insulin Dependent, Heart Diseases, Atherosclerosis
- Trial name
- NCT00037258
- Sponsor
- Brigham and Women's Hospital
Sepsis, Septic Shock
Sepsis in ICU:Causes and Outcomes of Sepsis in Diabetics Versus Non Diabetics in Assiut University Hospital
Clarify different causes of sepsis in patients admitted to ICU . as well asCompare causes and outcomes of sepsis between diabetics versus non diabetics .
- Trial name
- NCT04015752
- Testing
- culture from infected site
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetes, STEMI
Sweetheart-Register: Risk Management of Diabetics with Acute Myocardial Infarction
The Sweetheart register (Risk management of Diabetics with acute myocardial infarction) documents both the prevalence of pathologic glucose metabolism in consecutive high-risk patients with STEMI and NSTEMI in daily hospital…
- Conditions
- Diabetes, STEMI, NSTEMI, Myocardial Infarction
- Trial name
- Sweetheart (NCT01197742)
- Where
- 2 sites in Germany
- Volunteers
- 2,772 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Ophthalmology, Macular Edema
Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF Therapy
POLARIS : A non-interventional study in patients with diabetic macular edema (DME) with central involvement to assess the effectiveness of existing anti-vascular endothelial growth factor (anti-VEGF) treatment regimens.
- Conditions
- Ophthalmology, Macular Edema, Macular Degeneration
- Trial name
- POLARIS (NCT01771081)
- Testing
- Ranibizumab (or other DME treatment)
- Where
- 8 sites in France, Germany and 6 more
- Volunteers
- 911 people
- Sponsor
- Bayer
Eye Diseases, Retinitis Pigmentosa
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION
This trial will study the safety and efficacy of intranasal delivery of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes for the treatment of non-arteritic ischemic optic neuropathy
- Conditions
- Eye Diseases, Retinitis Pigmentosa, Diabetic Retinopathy, Macular Degeneration
- Trial name
- NCT05147701
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Diabetic Retinopathy
Diabetic Retinopathy and Diabetic Macular Edema Screening by Non-Physicians With Limited Training
The purpose is to assess accuracy of digital retinal image interpretation by technicians and direct ophthalmoscopy by nurses for the determination of diabetic retinopathy severity and the presence of diabetic macular edema for…
- Trial name
- NCT00500097
- Testing
- Digital retina image, direct ophthalmoscopy, comprehensive eye exam
- Where
- Thailand
- Volunteers
- 840 people
- Sponsor
- Ministry of Health, Thailand
Diabetes, Diabetes Mellitus, Type 2
Safety of NovoMix® 30 or Levemir® for Treatment of Type 2 Diabetics in Macedonia
This study is conducted in Europe. The aim of this observational study is to investigate the incidence of serious adverse drug reactions when using NovoMix® 30 (biphasic insulin aspart 30) or Levemir® (insulin detemir) for…
- Trial name
- NCT00842894
- Testing
- insulin detemir, biphasic insulin aspart 30
- Where
- North Macedonia
- Volunteers
- 3,421 people
- Sponsor
- Novo Nordisk A/S
Cystic Fibrosis, Impaired Glucose Tolerance
Cystic Fibrosis (CF) Exacerbation and Insulin Treatment
The purpose of the study is to evaluate whether insulin treatment during pulmonary exacerbation (PE) in patients with Cystic Fibrosis (CF)and normoglycemia improves their short term outcome by normalizing the glycemic profile and…
- Conditions
- Cystic Fibrosis, Impaired Glucose Tolerance, Pulmonary Exacerbation
- Trial name
- NCT01149005
- Testing
- novorapid / humalog short acting insulin, Novo Rapid Insulin (Novonordisk)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Autoantibody Positive, Non-diabetic Relatives at Risk for Type 1 Diabetes
Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
The study will determine whether the anti-CD3 monoclonal antibody, teplizumab, can help to prevent or delay the onset of type 1 diabetes (T1D) in relatives determined to be at very high risk for developing the disease.
- Conditions
- Autoantibody Positive, Non-diabetic Relatives at Risk for Type 1 Diabetes, High Risk, Impaired Glucose Tolerance
- Trial name
- NCT01030861
- Testing
- Teplizumab
- Where
- 19 sites in United States, Canada and 1 more
- Volunteers
- 76 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes
Comparison of the Use of Energy Substrates and Hormonal Regulation of Blood Sugar During Exercise of Increasing Intensity Between Children With Type 1 Diabetes and Non-diabetic Control Children.
The type 1 diabetes is a common chronic disease characterised by the stop of production of insulin by the pancreas. A lot of factors modify blood glucose.
- Trial name
- DIABSPORT (NCT03139864)
- Testing
- controlled physical activity
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Shock, Preterm Birth Complication
Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial
The goal of this clinical trial is to determine the effectiveness of early use of hydrocortisone (since the diagnosis of shock) for its resolution within the first 72 hours in premature infants under 1,500 g.
- Conditions
- Shock, Preterm Birth Complication, Preterm Intraventricular Hemorrhage, Asphyxia Perinatal
- Trial name
- NCT07248761
- Testing
- Intravascular Hydrocortisone (stress dosage): 1 mg/k/dose each 8 hours for 5 days, Vasoactive drug therapies
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Coronary Atheroscleroses
Postprandial Triglyceride Impact on Coronary Atherosclerosis in Non-Diabetic Patient in Sohag University Hospital
INTRODUCTION Cardiovascular diseases, including coronary artery disease (CAD), are the leading cause of mortality worldwide. Despite remarkable advancements in diagnostic and therapeutic approaches, CAD continues to pose…
- Trial name
- NCT06501287
- Testing
- Postprandial triglyceride
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Fatma Madhy Eissa
Non-Proliferative Diabetic Retinopathy
Intravitreal and Intracameral DEX in NPDR
To investigate the effects of intravitreal and intracameral injection of dexamethasone during cataract phacoemulsification in patients with mild to moderate non-proliferative diabetic retinopathy
- Trial name
- NCT06951087
- Testing
- Dexamethasone sodium phosphate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Diabetes Mellitus, Diabetic Neuropathies
Integrated Oral Care Intervention for Xerostomia in Diabetes Patients
Diabetes patients commonly experience dry mouth also known as xerostomia which can affect eating speaking oral health and overall quality of life.
- Trial name
- IOCID (NCT07425275)
- Testing
- Integrated Oral Care Intervention
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Khyber Medical University Peshawar
Kidney Diseases
China Kidney Patient Trials Network
This is a prospective multi-centre, observational cohort study of incident and prevalent patients diagnosed with a kidney disease in China.
- Trial name
- CKPTN (NCT05036850)
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- George (Beijing) Clinical Research Co. Ltd.
Pain, Infant, Newborn
Using Sugar Water to Relieve Pain in Infants
This study will examine the safety and effectiveness of sugar water to relieve pain in newborn infants during painful blood tests and injections.
- Conditions
- Pain, Infant, Newborn, Diabetes
- Trial name
- NCT00213213
- Testing
- Sucrose
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- The Hospital for Sick Children