Clinical trials: Neurocognitive Function
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common…
- Trial name
- NCT00916851
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognition Disorders
PET Scan to Map the Areas of the Brain Involved in Planning
Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of normal…
- Trial name
- NCT00001363
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Ondine Syndrome (Congenital Central Hypoventilation Syndrome)
Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)
This study investigates whether cognitive dysfunction in young patients with congenital central hypoventilation syndrome (Ondine Syndrome) is related to the severity of the disease and dysfunction of the locus coeruleus (a…
- Trial name
- ONDINE-LC (NCT07081464)
- Testing
- MRI, EEG, Pupillometry
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ADHD, Cognitive Deficit
Cognitive Intervention in Attention Deficit and Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder is a disorder in which children show insufficient attention span, hyperactivity and impulsivity according to their developmental level.
- Trial name
- NCT05063669
- Testing
- Cognitive Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Biruni University
Psychiatric Diagnosis, Cognition Disorders
Mood and Cognitive Outcome After Heart Transplantation (the MOODHEART Study)
The investigators aim at characterizing neuropsychiatric consequences of heart transplantation (HTX) and at assessing the impact of depressive symptoms after HTX on mortality and cardiac allograft vasculopathy (CAV).
- Trial name
- NCT02035865
- Where
- Norway
- Volunteers
- 74 people
- Sponsor
- Oslo University Hospital
Mild Neurocognitive Disorder
Effectiveness of a Novel Exergame-Based Training Concept for Older Adults With Mild Neurocognitive Disorder
BACKGROUND: Simultaneous motor-cognitive training interventions are considered promising to prevent the decline in cognitive functioning in older adults with mild neurocognitive disorder (mNCD) and can be highly motivating when…
- Trial name
- NCT05387057
- Testing
- Exergame training according to the 'Brain-IT' exergame-based training concept, Usual Care
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Eling DeBruin
Alzheimer's Disease, Healthy
The Effect of Acetylcholine on Memory and Attention
This study will examine whether enhancing the chemical acetylcholine in the brain can improve memory and attention. It will identify changes in brain function that occur during these cognitive tasks.
- Trial name
- NCT00001977
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
RATIONALE: Modafinil may help improve memory, attention, and fatigue caused by cancer treatment. PURPOSE: This phase II randomized trial studies how well modafinil works in treating children with memory and attention problems…
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Fatigue, Neurotoxicity
- Trial name
- NCT01381718
- Testing
- modafinil
- Where
- 60 sites in United States
- Volunteers
- 112 people
- Sponsor
- University of South Florida
Consciousness Disorder, Cognitive Impairment
Neurophysiological Evaluation of Residual Cognitive Functions in Patients With Severe Alterations of Consciousness
Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.
- Trial name
- NCT05802524
- Testing
- Neurowave Group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Athlete Assessment, Archery
Validity and Test-Retest Reliability of Reactive Neurocognitive Upper Extremity Tests in Archers
In archery, the evaluation of reaction time and neurocognitive functions plays a critical role in the management of upper extremity (UE) injuries and return-to-play (RTP) processes.
- Conditions
- Athlete Assessment, Archery, Neurocognitive Functional Performance Tests
- Trial name
- NCT07103824
- Testing
- Upper Extremity Neurocognitive Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Postoperative Cognitive Dysfunction
Comparison of Desflurane With Sevoflurane for School-age Children in Postoperative Cognitive Function
This study compares desflurane with sevoflurane for school-age children in postoperative cognitive function.
- Trial name
- NCT02909413
- Testing
- Desflurane, sevoflurane
- Volunteers
- 600 people
- Sponsor
- Shengjing Hospital
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Background: Neurocognitive disorders affect how the brain uses oxygen. They may affect mental development in children. These disorders can be studied with imaging scans that use radiation; however, these methods are not ideal for…
- Conditions
- Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome, Creatine Transporter Deficiency, Niemann-Pick Disease Type C1
- Trial name
- NCT05642221
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Alzheimers Disease, Periodontitis
EFFECT OF PERIODONTAL TREATMENT ON ALZHEIMER DISEASE-ASSOCIATED OUTCOMES
Periodontitis is the most prevalent chronic infectious inflammatory disease in adults, leading to the destruction of tooth-supporting tissues.
- Trial name
- PETAL (NCT07233512)
- Testing
- INITIAL PERIODONTAL THERAPY
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Postoperative Delirium, Cardiac Surgical Procedures
Dynamic Multimodal Delirium Warning After Cardiac Surgery
After heart surgery, up to half of all patients may develop a state of sudden confusion called postoperative delirium. This condition can lead to longer time on a breathing machine, extended stays in the intensive care unit…
- Trial name
- DEW-POD (NCT07686900)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southeast University, China
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Moyamoya Disease, Revascularization
The Evolution and Prognosis of Moyamoya Disease
To investigate the evolution of imaging appearances and cognitive function of Moyamoya disease (MMD) and to establish a prognosis evaluation system based on imaging biomarkers in MMD.
- Conditions
- Moyamoya Disease, Revascularization, Cognitive Impairment, Functional Impairment
- Trial name
- NCT05619068
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Diabetes Mellitus, Type 1, Diabetes
Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes
What are the effects of transient insulin deprivation on brain structure, blood flow, mitochondrial function, and cognitive function in T1DM patients? What are the effects of transient insulin deprivation on circulating exosomes…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes, Diabetes Complications
- Trial name
- NCT03392441
- Testing
- Insulin Deprivation in Type 1 Diabetic Patients
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Central Fatigue, Altitude Training
Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan).
- Conditions
- Central Fatigue, Altitude Training, Cognitive Impairment, Hydrotherapy
- Trial name
- HSCF-AHT (NCT07615478)
- Testing
- Natural recovery, Hot water immersion, Hot spring balneotherapy
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Intracranial Central Nervous System Disorder, Mental Disorder
Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex
This study will examine the underlying mental processes that determine how people understand social behavior, remember information, and think.
- Conditions
- Intracranial Central Nervous System Disorder, Mental Disorder, Healthy
- Trial name
- NCT00024908
- Where
- United States
- Volunteers
- 949 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)