Clinical trials: Needle Biopsy
Klatskin Tumor, Cholangiocarcinoma
Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma
This is an observational study with a prospective cohort design. This study enrolled patients with suspected hilar cholangiocarcinoma on imaging.
- Conditions
- Klatskin Tumor, Cholangiocarcinoma, Biopsy, Fine-Needle, Endoscopic Retrograde Cholangiopancreatography
- Trial name
- NCT05993429
- Testing
- The sampling method selected in patients with suspected hilar cholangiocarcinoma
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qilu Hospital of Shandong University
Benign Prostate Hyperplasia
A Trial Assessing Peri-procedure Chemoprophylaxis During Transrectal Prostate Needle Biopsy
The aim of the study is to evaluate whether changing antibiotic prophylaxis from fluoroquinolones alone to fluoroquinolones plus gentamicin 160mg single IM dose or targeted antibiotic prophylaxis according to rectal swab culture…
- Trial name
- NCT02423759
- Testing
- ciprofloxacin, ciprofloxacin and gentamycine, culture based chemoprophylaxis
- Where
- Egypt
- Volunteers
- 510 people
- Sponsor
- Mansoura University
Focus: Breast Cancer With Axillary Node Metastasis
Ultrasound Guided Core Biopsy vs Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy
The study was performed to determine if either ultrasound guided core biopsy or fine needle aspiration of an axillary lymph node has superior sensitivity in detecting metastatic carcinoma from the ipsilateral breast.
- Trial name
- NCT01920139
- Testing
- Fine needle aspiration and core biopsy of lymph node, Axillary surgery, Titanium marker
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Pittsburgh
Prostatic Cancer
Cleaning the Biopsy Needle in TRUS Bx
Prostate cancer(PCa) is the second most common cancer diagnosed in men. Clinical suspicion of PCa is mentioned in patients with digital rectal examination findings and elevated serum PSA.
- Trial name
- NCT06836271
- Testing
- Isopropyl Alcohol, Povidine-iodine, formaldehit
- Volunteers
- 200 people
- Sponsor
- Hitit University
Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer
Studies on Tumors of the Thyroid
Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid…
- Conditions
- Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer, Follicular Thyroid Cancer, Thyroid Cancer
- Trial name
- NCT00001160
- Testing
- 68-Gallium Dotatate
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Abdominal Neoplasms
22 Gauge Needle for EUS Guided Tissue Acquisition of Samples for Histologic Examination
To determine the yield of tissue biopsy specimen and the diagnostic accuracy of tissue acquisition using a newly developed 22 gauge needle in patients with solid lesions throughout the GI tract.
- Trial name
- EUSFNTA (NCT04032951)
- Testing
- Fine Needle Tissue Acquisition
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Needle Biopsy, CAT Scan
Breathing Cycle Biofeedback During Computed Tomography Procedures
This study will evaluate the effectiveness of a flexible belt device in guiding patient breathing during computed tomography (CT)-guided needle biopsy.
- Conditions
- Needle Biopsy, CAT Scan, X-Ray
- Trial name
- NCT00059137
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Thyroid Nodule
Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules
The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.
- Trial name
- NCT00571090
- Testing
- Thyroid ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 735 people
- Sponsor
- Istanbul Science University
Thoracic Neoplasms
Role of Ultrasound Guided Peripheral Thoracic Tumors
The aim of the study was to calculate sensitivity, and accuracy of ultrasound guided percutaneous core needle biopsy in different thoracic tumors (lung, pleural, chest wall and mediastinal).
- Trial name
- NCT04741958
- Testing
- Ultrasound Guided Peripheral Thoracic Tumors
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Premalignant Lesion
High-risk Breast Lesions: A Multicenter Retrospective Study
In this multicenter study, the goal was to document the excisional biopsy or follow-up results of high risk lesions diagnosed on image guided CNB/VAB, and evaluate the clinical, imaging and histologic features for associated…
- Trial name
- NCT04926688
- Where
- Turkey (Türkiye)
- Volunteers
- 1,345 people
- Sponsor
- Ege University
Endometrial Hyperplasia
Comparison of Dilatation & Curettage and Endometrial Aspiration Biopsy Accuracy in Patients Treated With Progestin for Endometrial Hyperplasia: A Korean Gynecologic Oncology Group Study
A prospective multicenter trial has been started in Korea to evaluate the diagnostic accuracy of endometrial aspiration biopsy compared with D\&C in patients treated with progestin for endometrial hyperplasia (EH).
- Trial name
- NCT02412072
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Korean Gynecologic Oncology Group
Gastrointestinal Tract, Gastrointestinal Stromal Tumor
Feasibility and Yield of a New 20 G ProCore Needle With Coiled Sheath in the Gastrointestinal Subepithelial Tumors
The exact incidence of subepithelial tumors (SETs) in the gastrointestinal (GI) tract is unknown, but the prevalence of gastric SETs detected during routine esophagogastroduodenoscopy is 0.36%.
- Trial name
- NCT02884154
- Testing
- Echotip ProCoreⓇ HD Ultrasound Biopsy Needle
- Volunteers
- 39 people
- Sponsor
- Pusan National University Hospital
Endometrial Cancer
Compare the Performance of Targeted Biopsy Versus Aspiration Biopsy With a Pipette for the Diagnosis of Endometrial Cancer
Endometrial cancer is the most common pelvic gynecological cancer in so-called developed countries, with 320,000 new cases annually, including more than 1,500 in Belgium. It preferentially affects postmenopausal women.
- Trial name
- NCT03115593
- Testing
- Blind biopsy with a pipette, Targeted biopsy using hysteroscopy
- Where
- 4 sites in Belgium, France
- Sponsor
- Brugmann University Hospital
Invasive Breast Cancer
Comparison of CNB and Surgical Specimens for ER, PgR, HER2 Status and Ki67 Index in Invasive Breast Cancer.
This is a prospective, single-center, non-randomized, non-controlled study. The estrogen receptor (ER), progesterone receptor (PgR), HER2 status and Ki67 index of CNB specimen are critical biomarkers for making neoadjuvant…
- Trial name
- NCT02773784
- Testing
- immunohistochemistry and/or FISH
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Peking University
Orbial Mass Lesion
Effectiveness and Possible Complications of Core Needle Biopsy of Orbital Tumors
Core needle biopsy of orbital mass lesions with a semiautomated needles is a safe procedure that provides a sufficient amount of tissue material for standard histological and immunohistochemical analysis and can be an alternative…
- Trial name
- NCT01772355
- Testing
- semi automated core needle biopsy of orbital tumors
- Where
- Russia
- Volunteers
- 75 people
- Sponsor
- Yarovoy Andrey
Breast Cancer
The Accuracy of Sentinel Node Biopsy of Breast Cancer With Sonographic Abnormal Axillary Lymph Nodes
This is a phase II, prospective, single-center, non-randomized, non-controlled study. Sentinel lymph node biopsy (SNB) is a standard staging procedure in early breast cancer.
- Trial name
- NCT02005926
- Testing
- Wire-localized abnormal node
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tao OUYANG
Soft Tissue Sarcoma of the Limb
Biopsy Needle Size in Soft Tissue Sarcoma
Soft tissue sarcomas (STS) require accurate biopsy for diagnosis, grading, and management decisions. Although tru-cut biopsy is widely used, the optimal needle gauge remains uncertain.
- Trial name
- NCT07066774
- Testing
- Tru-cut Biopsy with 14 G Needle, Tru-cut Biopsy with 16G tru-cut needle, Tru-cut Biopsy with 18G tru-cut needle
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Cervical Intraepithelial Neoplasia
Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion
The purpose of this trial is to determine whether SWETZ (Straight Wire Excision of Transformation Zone) is a superior alternative to LLETZ cone (Large Loop Excision of Transformation Zone cone biopsy) in the management of…
- Trial name
- NCT00995020
- Testing
- Straight Wire Excision of Transformation Zone, Large Loop Excision of Transformation Zone (cone biopsy)
- Where
- 2 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Oswaldo Cruz Foundation
Hepatic Lesions
Comparative Diagnostic Yield of Contrast-Enhanced Versus Conventional Ultrasound Guidance for Coaxial Biopsy of Hepatic Lesions
This study compared two methods used to guide needle biopsies of suspicious lumps (lesions) in the liver. A biopsy is a procedure where a small sample of tissue is taken to make a diagnosis.
- Trial name
- NCT07249268
- Testing
- CEUS or Contrast enhanced Ultrasound, US
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Bone Marrow Aspiration and Biopsy Specimen Collection
A Study Comparing Use of Manual and Power Bone Marrow Aspiration and Biopsy Devices in Children
The purpose of this study is to compare use of a powered bone marrow aspiration and biopsy device (OnControl) to use of a standard manual bone marrow aspiration and biopsy device to obtain bone marrow biopsy specimens in…
- Trial name
- NCT02159118
- Testing
- Manual bone marrow aspiration and biopsy device, Powered bone marrow aspiration and biopsy device
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Vidacare Corporation