Clinical trials: Myopic Astigmatism
- Condition Myopic Astigmatism
- Funder type Industry (pharma, biotech, devices)
- Age group Children (under 18)
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Ametropia, Myopia
Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT06408649
- Testing
- Lehfilcon A spherical contact lenses, Lehfilcon A toric contact lenses
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism
The primary objective of the study is to evaluate and compare the performance of two soft contact lens.
- Conditions
- Astigmatism, Myopia, Hyperopia
- Trial name
- NCT06873048
- Testing
- Control Contact Lens (stenfilcon A Sphere), Test Contact Lens (stenfilcon A Toric)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Hyperopia
Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses
Bilateral dispensing clinical trial of fanfilcon A toric lens verses enfilcon A toric lens over two weeks.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT02423109
- Testing
- fanfilcon A, enfilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision, Inc.
Myopia
Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
The objective of this clinical investigation is to collect scientifically valid safety and effectiveness data on the Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear.
- Trial name
- Acuity200OK (NCT06009458)
- Testing
- Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 387 people
- Sponsor
- Acuity Polymers, Inc.
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter
To evaluate the clinical performance and user-reported experience of Paragon CRT contact lenses with a 5mm Optic Zone Diameter (OZD)
- Trial name
- NCT07751172
- Testing
- Lens A (paflufocon D)
- Where
- 3 sites in United States, Spain
- Volunteers
- 70 people
- Sponsor
- CooperVision International Limited (CVIL)
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Refractive Errors
Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric)…
- Trial name
- NCT06462456
- Testing
- Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Alcon Research
Myopia, Myopia, Moderate
Software Refraction With Mobilerone Versus Retinoscopy
Software refraction in the mobilerone for myopia and astigmatism is a novel medical device for myopia adults and elder children with or without astigmatism.
- Conditions
- Myopia, Myopia, Moderate, Astigmatism
- Trial name
- SRMR (NCT06059521)
- Testing
- Software refraction with Eye Test Technology in a mobilerone, Retinoscopy
- Where
- 3 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Prospective Study of an Investigational Toric Soft Contact Lens
The purpose of this study was to demonstrate substantial equivalence of an investigational toric soft contact lens to the commercially available Focus® DAILIES® Toric soft contact lens when worn in a daily wear, daily disposable…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01461811
- Testing
- Nelfilcon A toric contact lenses (with comfort additives), Nelfilcon A toric contact lenses
- Volunteers
- 154 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
The purpose of this study is to continuously assess the visual performance and safety of DAILIES TOTAL1 soft contact lenses in a real world setting and broader patient base through routine clinical practices.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT06483113
- Testing
- Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 192 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in gas permeable lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912781
- Testing
- FID 120947A contact lens disinfecting solution, Boston Simplus multi-action solution, Gas permeable contact lenses
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Effect of a Myopia Control Lens on the Astigmatism in Children
The goal of this clinical trial is to investigate over a one-year period the effect of myopia control spectacle lenses on astigmatism in children aged 6 to 13 years with myopia and astigmatism.
- Trial name
- MAC (NCT07810725)
- Testing
- Lenslet-based myopia control spectacle lens
- Volunteers
- 15 people
- Sponsor
- Essilor International
Myopia, Hyperopia
High Refractive Index Material 510(k)
The purpose of this study is to establish the substantial equivalence of the HDS HI 1.54™ to the paflufocon C material control lenses to correct myopia and hyperopia with and without astigmatism.
- Trial name
- PVS-07-07 (NCT00766168)
- Testing
- HDS HI 1.54; pahrifocon A, FluoroPerm 30 RGP; paflufocon C
- Where
- 8 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)