Clinical trials: Musculoskeletal Physiology
Balanced; Rearrangement, Respiratory Function Test
The Effect of Lycra Garment on Spastic Diplegic Cerebral Palsy Individuals With Scoliosis
The primary aim of this study was to investigate the effects of lycra clothing on balance and respiratory functions in individuals with cerebral palsy with scoliosis, and the secondary aim was to investigate the effects of lycra…
- Trial name
- NCT06295991
- Testing
- Lycra garment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Patellofemoral Pain Syndrome, Adolescents
Enhancing Stability and Function in Adolescent
This study investigated the comparative effects of proprioceptive neuromuscular facilitation (PNF) stretching and core strength exercises on static balance in adolescents with patellofemoral pain syndrome (PFPS).
- Trial name
- NCT06696872
- Testing
- core exercises, Proprioceptive Neuromuscular Facilitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Delta University for Science and Technology
Adolescent Idiopathic Scoliosis (AIS)
Investigation of Shoulder Position, Upper Extremity Proprioception, and Function in Adolescents With Idiopathic Scoliosis Using Braces
This study aims to investigate the effects of brace use on shoulder position, upper extremity proprioception, and upper extremity function in adolescents with idiopathic scoliosis.
- Trial name
- NCT06904157
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gözde Yagci (Gür)
Brain Tumor, Brain Cancer
Observational Trial of the Impact of Radiation Dose in Children With Brain and Skull Base Tumors.
This is a prospective, observational clinical trial investigating the morphological and volumetric changes in the brain following cranial Radiation Therapy in pediatric patients with brain or skull base tumors.
- Conditions
- Brain Tumor, Brain Cancer, Skull Base Tumor
- Trial name
- NCT03972514
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baptist Health South Florida
Duchenne Muscular Dystrophy, Cardiomyopathies
The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy
Purpose This cardiac dysfunction in patients with Duchenne muscular dystrophy is associated with minor cardiac damage as indicated by elevation of plasma cardiac troponin I (cTnI).
- Trial name
- NCT00606775
- Testing
- Carvedilol
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Suzuka Hospital
Muscle Spasticity, Cerebral Palsy
Radial Extracorporeal Shock Wave Therapy for Spastic Plantar Flexor Muscles in Young Children With Cerebral Palsy
The purpose of this study is to determine whether radial extracorporeal shock wave therapy in combination with traditional physical therapy is safe and effective for the management of spastic plantar flexor muscles in patients…
- Trial name
- NCT02719483
- Testing
- Swiss DolorClast, Traditional conservative therapy
- Volunteers
- 66 people
- Sponsor
- The First Hospital of Jilin University
Patellofemoral Pain Syndrome, Anterior Knee Pain
Elite Athletes: Trunk Mobility, Lower Extremity Flexibility, and Functional Balance Across Sports
This cross-sectional observational study investigated the relationships among dynamic Q angle, core muscle endurance, hip flexibility, and lower extremity functional status in elite adolescent athletes with and without…
- Trial name
- NCT07326046
- Where
- Cyprus
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cleft Palate
Furlow With Buccinator and Velopharyngeal Function
Assessment of speech and the middle ear function of patients between the age of 3 and 7 years surgically treated by ARC (Furlow z-palatoplasty with a buccinator myomucosal flap) was done.
- Trial name
- NCT06229587
- Testing
- furlow with buccinator flap
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar
Spasticity
Kinesiotaping the Hand in Cerebral Palsy
BACKROUNDS: Thumb in palm deformity restricts hand function by prevent somatosensory input in the children with cerebral palsy who have spasticity in their hands.
- Trial name
- NCT02073513
- Testing
- Kinesiotape plus thenar pressure (PPTG), Taping Group (TG)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Eosinophilia-Myalgia Syndrome
L-5-HTP-Related EMS
In 1989 more than 1500 people who took the dietary supplement L-tryptophan for insomnia and depression developed eosinophilia myalgia syndrome (EMS)-a potentially fatal disease characterized by an excess of a type of white blood…
- Trial name
- NCT00001918
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Mental Health (NIMH)
Arthrogryposis Multiplex Congenita, Piezo2 Mutation Gain of Function
Piezo2-related Arthrogryposis & physiopathOLOgy 3
Study type: Observational, non-interventional, single-center, descriptive study. Goal of the study: The goal of this observational study is to characterize the intensity, variability, and qualitative features of pain in patients…
- Trial name
- PAOLO3 (NCT07360574)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Grenoble
Duchenne Muscular Dystrophy (DMD), Muscular Dystrophy, Duchenne
Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)
The purpose of the study is to assess the efficacy, safety, and tolerability of zeleciment rostudirsen (DYNE-251) administered intravenously (IV) every 4 weeks to ambulatory Duchenne muscular dystrophy (DMD) participants, 4 to 18…
- Conditions
- Duchenne Muscular Dystrophy (DMD), Muscular Dystrophy, Duchenne, Muscular Dystrophy (DMD), DMD
- Trial name
- FORZETTO (NCT07608432)
- Testing
- Zeleciment Rostudirsen (DYNE-251)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Dyne Therapeutics
Duchenne Muscular Dystrophy
Observational Study of Patients With Duchenne Muscular Dystrophy Theoretically Treatable With Exon 53 Skipping
PreU7-53 is a natural history study. The objective is to monitor the clinical and radiological course of upper limb muscle impairment in patients with Duchenne Muscular Dystrophy (DMD), potentially treatable with AAV-mediated…
- Trial name
- pre U7-53 (NCT01385917)
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 45 people
- Sponsor
- Genethon
Duchenne Muscular Dystrophy
Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin
The purpose of the study is to show that the intake of L-arginine and metformin improves muscle function and delays disease progression in patients with Duchenne's muscular dystrophy.
- Trial name
- NCT02516085
- Testing
- Metformin, L-Arginine
- Volunteers
- 5 people
- Sponsor
- University Hospital, Basel, Switzerland
Duchenne Muscular Dystrophy, Duchenne Disease
Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients
This pilot study will investigate the potential efficacy of VM100, a nutritional supplement specifically formulated for patients with DMD, on quality of life and physical symptoms.
- Conditions
- Duchenne Muscular Dystrophy, Duchenne Disease, Muscular Dystrophy in Children, DMD
- Trial name
- NCT07766980
- Testing
- VM100 Nutritional Supplement
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy
Wearable Technology to Assess Gait Function in SMA and DMD
The purpose of this project is to devise instrumented insoles capable of accurately measuring gait at each footfall, over multiple hours in any environment.
- Trial name
- NCT04193085
- Testing
- Observational
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cerebral Palsy, Anxiety
Does Anxiety Affect Balance, Spasticity and Function in Children With Cerebral Palsy
children and adolescents with CP are at increased risk of developing mental health difficulties, particularly anxiety disorders, compared with their typically developing peers.
- Conditions
- Cerebral Palsy, Anxiety, Spasticity
- Trial name
- NCT07346430
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Scoliosis Idiopathic, Scoliosis; Adolescence
Back Muscle Function in Adolescents With Idiopathic Scoliosis
The function and asymmetry of back muscles will be examined in different positions and with specific spinal corrections based on scoliosis pattern and according to the "Schroth method" in adolescents with idiopathic scoliosis.
- Trial name
- NCT05961228
- Testing
- exercise
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Haifa