Clinical trials: Memory Disorders
Pediatric Iron Deficiency, Anemia
Choline and Iron Deficiency
BACKGROUND: Iron deficiency limits the neurodevelopmental potential of more than 200 million children each year. Iron therapy is typically started when iron deficiency anemia is first diagnosed after screening for anemia or…
- Trial name
- NCT06527391
- Testing
- choline bitartrate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Diabetes Mellitus, Type 1
A Study on the Effect of 2 Pen Devices on HbA1c
The purpose of this study is to test the hypothesis that the HumaPen Memoir with memory function, when used over 24 weeks for prandial insulin injections achieves superior glycemic control, when compared to the conventional…
- Trial name
- NCT00985712
- Testing
- Insulin Lispro, Huminsulin Regular, HumaPen Memoir
- Where
- 29 sites in Germany
- Volunteers
- 263 people
- Sponsor
- Eli Lilly and Company
Japanese Encephalitis, Varicella
Study of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Previously Immunized With JE-CV
The aim of the study is to investigate the memory immune response and the yearly persistence of the immunity against Japanese Encephalitis (JE) after vaccination with Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in…
- Trial name
- NCT01190228
- Testing
- JE-CV Vaccine, Varicella Vaccine
- Where
- Philippines
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Dental Anxiety
Efficacy of Oral Midazolam for Sedation and Amnesia in Preschool Children Undergoing Dental Procedures
Dental anxiety frequently impedes effective dental care in pediatric patients. This study aimed to compare the efficacy and safety of two doses (0.3 mg/kg and 0.6 mg/kg) of oral midazolam for sedation and amnesia in preschool…
- Trial name
- NCT06887712
- Testing
- Oral midazolam
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Hanoi Medical University
Benign Epilepsy With Centro Temporal Spikes (BECTS), Atypical Benign Partial Epilepsy (ABPE)
Sleep Related Memory Consolidation in Children With Age Related Focal Epilepsy.
Age related focal epilepsies in children encompasses, according to the ILAE criteria, benign epilepsy with centro temporal spikes (BECTS), atypical benign partial epilepsy (ABPE) and epileptic encephalopathy with continuous spike…
- Conditions
- Benign Epilepsy With Centro Temporal Spikes (BECTS), Atypical Benign Partial Epilepsy (ABPE), Epileptic Encephalopathy With Continuous Spike and Waves During Sleep (ECSWS)
- Trial name
- EPIMEM (NCT03865771)
- Testing
- Neuropsychological testing, Neuropsychological procedure, Video EEG and polysomnography
- Where
- 2 sites in France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Strasbourg, France
Brain Tumor, Pediatric
Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention
This is a prospective, open-label, multicentric study designed to correlate the dose delivered to the hippocampus with declarative memory deficits 2 years after radiotherapy treatment in a paediatric population who had received…
- Trial name
- IPANEMA (NCT06599879)
- Testing
- Neuropsychological assessments:
- Where
- 14 sites in France
- Volunteers
- 130 people
- Sponsor
- Institut Claudius Regaud
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cancer Brain, Pediatric Cancer
Memory Neuroimaging in Children, Adolescents and Young Adults Following Pediatric Cancer
Brain tumours are the leading cause of cancer-related death and morbidity in children, adolescents and young adults. The brain is also one of the most sensitive organs to treatments used in pediatric oncology, even for cancers…
- Trial name
- IMPALA (NCT04324450)
- Testing
- MRI, Cognitive assessment
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Intellectual Disability, Perceptual Disorders
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
The purpose of this study is to determine the relationships between sedative exposure during pediatric critical illness and long-term neurocognitive outcomes.
- Conditions
- Intellectual Disability, Perceptual Disorders, Memory Disorders
- Trial name
- RESTORE-cog (NCT02225041)
- Where
- 31 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mild Cognitive Impairment
Evaluation of an Intervention for Living With Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a significant risk factor for dementia. Persons with MCI experience cognitive changes, most typically affecting memory; that are greater than those experienced in "normal" aging.
- Trial name
- NCT02083237
- Testing
- Behavioural Intervention Program
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Baycrest
Epilepsy Intractable
Pediatric Epilepsy
The purpose of the research is to better understand how the human brain accomplishes the basic cognitive tasks of learning new information, recalling stored information, making decisions or choices about presented information and…
- Trial name
- NCT07350551
- Testing
- Cedrus RB series response pad; Adtech Behnke-Fried micro-electrodes; Neuralynx or Blackrock electrophysiology system; Blackrock Cerestim or Natus Nicolet stimulator
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Acquired Brain Injury
Feasibility Randomized Trial for an Intensive Memory-Focused Training Program for School Aged Children With Acquired br.Inj.
Memory deficits are common sequelae of pediatric Acquired Brain Injury (ABI). Only methods for non-focused cognitive remediation are available to the pediatric field.
- Trial name
- NCT04206475
- Testing
- rehabilitation, Intensive Memory-Focused Training Program (IM-FTP)
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- IRCCS Eugenio Medea
Alzheimer's Disease, Aging
Memory Aid for Informed Consent in Alzheimer's Research
The purpose of this trial is to test whether a memory and organizational aid in the form of a document that summarizes and simplifies a study's key points can improve the decision-making abilities and competency of mild to early…
- Trial name
- NCT00105612
- Testing
- Memory and Organizational Aid, Standard Informed Consent Process
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Institute on Aging (NIA)
Dementia, Cognitive Decline
Ammonia Levels and Cognitive Impairment
The purpose and objective of this study is to determine the prevalence of elevated ammonia levels in subjects with cognitive impairment, and to observe if treating the cause of the elevated ammonia level improves mental status.
- Conditions
- Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
- Trial name
- NCT02059356
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Obesity, Adolescent
Increased Protein at Breakfast for Weight Management in Overweight Adolescents
Adolescent obesity, negatively affecting the lives of over 18 million (34%) US adolescents, continues to be a major public health concern due to the increased risk of developing chronic diseases, including type 2 diabetes.
- Trial name
- NCT03146442
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alzheimer's Disease
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease
It is widely believed that inflammation contributes to the pathogenesis of AD. TNF has been implicated in both AD and neurological inflammation. Anti-TNF therapy is therefore surmised to be of potential benefit for treating AD.
- Trial name
- NCT00203359
- Testing
- etanercept given by perispinal administration
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tobinick, Edward Lewis, M.D.
Pediatric Cancer
Efficacy of Cognitive and Physical Trainings in Pediatric Cancer Survivors
Cancer survival comes at a price: pediatric cancer survivors have a high risk for a wide range of cognitive difficulties, particularly survivors of cancer involving the central nervous system (CNS, e.g., brain tumors [BT]) are…
- Trial name
- NCT02749877
- Testing
- Working Memory Training, Physical Training
- Where
- Switzerland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Alzheimer's Disease
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease
It is widely believed that inflammation contributes to the pathogenesis of AD. TNF has been implicated in both AD and neurological inflammation. Anti-TNF therapy is therefore surmised to be of potential benefit for treating AD.
- Trial name
- NCT00203320
- Testing
- etanercept given by perispinal administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tobinick, Edward Lewis, M.D.
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Alzheimer's Disease
Trial of Carvedilol in Alzheimer's Disease
This is a 6-month pilot randomized double-blind placebo-controlled trial of carvedilol, with the primary objective being to determine whether carvedilol treatment is associated with improvement in Alzheimer's Disease (AD) as…
- Trial name
- NCT01354444
- Testing
- Carvedilol
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Johns Hopkins University