Clinical trials: Maternal Health
Exclusive Breastfeeding, Co-production of Health in Communities
A Mobile-health Pilot Experiment Targeting Mothers With Newborns in Rural Areas of San Juan Sacatepequez, Guatemala
The purpose of this study was to determine whether exposure to m-health platforms promoting recommended breastfeeding practices was effective in transmitting the exclusive breastfeeding message to participant mothers, and in…
- Trial name
- NCT02263118
- Testing
- Uni-directional SMS, Feature phone, Virtual communities
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco Marroquín
Sepsis
Zambia Chlorhexidine Application Trial
This will be a cluster-randomized controlled trial to assess whether washing the umbilical cord with a disinfectant (4% chlorhexidine) helps to reduce neonatal deaths in Zambia when compared to the current standard of care, dry…
- Trial name
- ZamCAT (NCT01241318)
- Testing
- Chlorhexidine gluconate (4%), Dry cord care
- Where
- Zambia
- Volunteers
- 77,535 people, healthy volunteers welcome
- Sponsor
- Boston University
Obesity, Obesity, Childhood
Healthy Homes, Healthy Habits
The purpose of this study is to evaluate whether an intervention targeting healthy habit development reduces the risk and prevalence of obesity in low-income mothers and children.
- Conditions
- Obesity, Obesity, Childhood, Obesity; Familial
- Trial name
- HABITS (NCT03433456)
- Testing
- Home visitation + HABITS program, Standard home visitation program
- Where
- United States
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV, Hypertension
SEARCH SAPPHIRE Phase A: A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa
The randomized trials in this record will assess effectiveness, fidelity and cost of prevention and treatment interventions for HIV and hypertension with the objective of informing a population-based study of multi-sectored…
- Conditions
- HIV, Hypertension, Alcohol Drinking, Maternal Child Health
- Trial name
- SAPPHIRE PhA (NCT04810650)
- Testing
- Mobility Dynamic Treatment Intervention, Health Living Intervention for Heavy Alcohol Users, Hypertension Linkage
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 2,233 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity, Obesity, Childhood
In-home Obesity Prevention to Reach Low-income Infants
Existing obesity prevention efforts have had limited success among underserved, low-income children. This study capitalizes on the strengths of a nationwide ongoing Home Visitation Program (HVP), which serves at-risk, low-income…
- Conditions
- Obesity, Obesity, Childhood, Obesity; Familial
- Trial name
- NCT03529695
- Testing
- Standard HVP Curriculum, Obesity Prevention
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Birth Setting, Maternal Health
Traditional Ethiopian Coffee Ceremony in a Rural Ethiopian Hospital to Increase Hospital-based Delivery Rates
This study evaluates if organizing a postpartum traditional Ethiopian coffee ceremony will provide an incentive for our antenatal care patients to eventually deliver in our hospital.
- Trial name
- NCT04232137
- Testing
- Postpartum coffee ceremony
- Volunteers
- 439 people
- Sponsor
- Vanderbilt University Medical Center
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development
Maternal Adversity, Vulnerability and Neurodevelopment
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development, Infant Behavior
- Trial name
- MAVAN (NCT03434457)
- Where
- Canada
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
mHealth, PMTCT
Mobile Strategies for Women's and Children's Health: Optimizing Adherence and Efficacy of PMTCT/ART
The investigators are conducting a 3-arm randomized trial comparing the effects of unidirectional SMS (ie: "push" messaging to participant) vs. bidirectional SMS dialogue between participant and provider vs.
- Conditions
- mHealth, PMTCT, Adherence, Medication, SMS
- Trial name
- Mobile WAChx (NCT02400671)
- Testing
- SMS messaging
- Where
- 6 sites in Kenya
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Mother-infant Relational Disturbances
Mother-Infant Psychoanalysis Project of Stockholm
Mother-infant relationship disturbances broadly comprise three areas; maternal distress, infant functional problems, and relationship difficulties.
- Trial name
- MIPPS (NCT00923559)
- Testing
- Treatment as Usual at Child Health Centre, Mother-Infant Psychoanalytic treatment (MIP)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Maternal Sepsis, Neonatal Sepsis
Smart Discharges for Mom & Baby
This study aims to build a predictive algorithm that identifies mother-newborn dyads most at risk of death or complications in the 6 weeks after birth.
- Trial name
- NCT05730387
- Testing
- Observational only
- Where
- Canada
- Volunteers
- 7,182 people
- Sponsor
- University of British Columbia
Mental Health Wellness 1, Pregnancy
Mellow Bumps RCT - Antenatal Intervention for Vulnerable Women
The purpose of this study is to compare the effectiveness of a relationships based antenatal intervention (Mellow Bumps) against a comparison intervention (Chillout In Pregnancy) and also against the normal antenatal care which…
- Conditions
- Mental Health Wellness 1, Pregnancy, Mother-Child Relations
- Trial name
- NCT01590212
- Testing
- Mellow Bumps, Chill-out in Pregnancy
- Where
- 2 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Glasgow
Postpartum Period
Involving Men in Maternity Care in Burkina Faso
The uptake of postpartum contraception, postpartum care attendance and the practice of exclusive breastfeeding are low in Sub-Saharan Africa.
- Trial name
- NCT02309489
- Testing
- Partner involvement
- Where
- Burkina Faso
- Volunteers
- 1,144 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Post-traumatic Stress Disorder, Alcohol Abuse
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Recent needs assessments suggest that difficulties exist in care coordination between emergency medical services (EMS) systems and primary care for injured adolescents with alcohol problems and post-traumatic stress disorder…
- Conditions
- Post-traumatic Stress Disorder, Alcohol Abuse, Alcohol Dependence
- Trial name
- ATRSCC (NCT00619255)
- Testing
- Adolescent Trauma Support Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Obesity, Maternal, Hypertension in Pregnancy
Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children
This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants.
- Conditions
- Obesity, Maternal, Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Diabetes
- Trial name
- NCT05473767
- Testing
- Family Check Up Heart, Family Check-Up
- Where
- 3 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Pittsburgh
Breastfeeding
Breast for Success: A Family-Centered Intervention in Support of Breastfeeding Among High-risk Low-income Mothers
Breast for Success is a new direct service program focused on overcoming barriers to breastfeeding for low-income inner-city mothers by use of a culturally competent and home-based educational and support intervention.
- Trial name
- BFS (NCT01272661)
- Testing
- Enhanced Curriculum, Enhanced Curriculum+Breastfeeding Doula, Enhanced Curriculum +Father Support
- Where
- United States
- Volunteers
- 1,296 people
- Sponsor
- University Hospitals Cleveland Medical Center
Pregnancy Related, Doula Care
Labor and Delivery Doula Program to Reduce Perinatal Morbidity and Mortality in Kansas
The study was done to learn how doula-enhanced care provided to Black birthing people improved perceived communication and quality care.
- Conditions
- Pregnancy Related, Doula Care, Black Maternal and Infant Health, Prenatal Care
- Trial name
- Doula (NCT07157059)
- Testing
- Doula Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Mental Disorders
Padres Efectivos (Parent Activation): Skills Latina Mothers Use to Get Healthcare for Their Children
The goal of this study is to develop an intervention to teach activation skills to Latino parents who bring children for mental health services.
- Trial name
- NCT02329431
- Testing
- activation curriculum, support group
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Stress
New Haven MOMS Partnership
Phase II of the MOMS Partnership aims to: 1. conduct a needs assessment of the mental health of mothers residing in New Haven, CT; 2.
- Trial name
- NCT01665872
- Testing
- Cognitive-Behavioral Group Therapy
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Yale University
Low Birthweight, Pre-Term
Low-birthweight Infant Feeding Exploration
Globally, 15% of all babies, amounting to 20 million infants each year, are born low birthweight (LBW), defined less than 2500 grams (5.5 lbs).
- Trial name
- LIFE (NCT04002908)
- Where
- 3 sites in India, Malawi and 1 more
- Volunteers
- 3,188 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)