Clinical trials: Major Abdominal Surgeries
Surgery, Aging
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
The researchers will conduct observations, interviews, and focus groups with clinicians, staff and patients of the Perioperative Optimization of Senior Health (POSH) clinic, which conducts preoperative comprehensive geriatric…
- Conditions
- Surgery, Aging, Health Care Utilization, Frailty
- Trial name
- NCT06184919
- Testing
- Process Mapping: Observations, Process Mapping: Interviews, Process Mapping: Focus Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Pediatric Cancer, Pain, Postoperative
Multimodal Analgesia in Major Abdominal Pediatric Cancer Surgeries
Surgical trauma initiates multiple physiological mechanisms that cause postoperative pain. Postoperative pain has nociceptive, inflammatory, and neuropathic components.Inadequate relief of postoperative pain leads to significant…
- Trial name
- NCT03580980
- Testing
- Paracetamol and ketamine, Caudal levobupivacaine, Morphine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Goal-directed Fluid Therapy
Effect of SVV-guided Fluid Therapy on Outcomes After Major Abdominal Surgery
The investigators conduct this randomized assessor-blinded controlled trial to evaluate the effect of SVV-guided fluid therapy on postoperative morbidity and mortality in comparison with conventional fluid therapy after major…
- Trial name
- NCT03940144
- Testing
- the enhanced flow-based hemodynamic parameters of the FloTrac/Vigileo device
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tongren Hospital
Surgery, Recovery
Postoperative Quality Recovery Scale (PQRS)
Recovery following general anesthesia and surgery is a complex issue confounded by the type of surgery, surgical care, inflammation, different anesthetic drugs and techniques, patient co-morbidities, and differing patient and…
- Trial name
- NCT01902147
- Testing
- Postoperative Quality Recovery Scale (PQRS)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Franco Carli
Gastric Tumor, Pancreatic Tumor
Parenteral Fish Oil in Major Laparoscopic Abdominal Surgery
The aim of this study is to assess the effect of postoperative parenteral fish oil on clinical outcome and immune function after major laparoscopic abdominal surgery.
- Conditions
- Gastric Tumor, Pancreatic Tumor, Liver Tumor
- Trial name
- NCT01819961
- Testing
- MCT/LCT and fish oil, MCT/LCT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wei Zhou
Parenteral Nutrition, Major Surgery
Perioperative TPN Improves Surgical Outcomes
Preoperative optimization of patients is a well known concept. Not all patients can tolerate feeds and as such TPN is given. TPN given preoperatively and continued postoperatively in selected group of patients can significantly…
- Conditions
- Parenteral Nutrition, Major Surgery, Malnutrition
- Trial name
- NCT06573632
- Testing
- TPN-N7 Baxter
- Where
- Nepal
- Volunteers
- 150 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Liver Transplant, Erector Spina Plan Block
Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients
The goal of this clinical trial is to learn if ESP block is safe and effective for perioperative analgesia in patients undergoing liver transplant.
- Trial name
- NCT06857331
- Testing
- Erector Spinae Plane Block using 0.2% ropivacaine
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Bogomolets National Medical University
Malnourishment, Gastrointestinal Tumors
The Impact of Preoperative Oral Glutamine Intake on the Immunocompetence and Outcomes of Malnourished Patients Undergoing Major Abdominal Surgery Due to Malignancies
Malnutrition occurs in up to 50% of patients requiring elective surgery for neoplastic diseases. It exerts a detrimental influence on outcome of surgery, because it can suppress immune function, exaggerate stress response and…
- Trial name
- Glutaminprojec (NCT01552291)
- Testing
- Glutamine
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia Induced Atelectasis
Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound
Atelectasis is a side effect of general anesthesia which can be found in all types of interventions and patients of all ages.1-3 The reported incidence of anesthesia- induced atelectasis in children varies, ranging from 12 to 42%…
- Trial name
- NCT03069157
- Testing
- lung recruitment maneuver
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Acute Pain
Duloxetine Potentiates the Analgesic Efficacy of Intrathecal Morphine
Duloxetine is a serotonin-norepinephrine reuptake inhibitor primarily used for treatment of major depression and anxiety. Duloxetine also has been used in the treatment of chronic pain conditions, such as osteoarthritis and…
- Trial name
- NCT03560427
- Testing
- Duloxetine 60mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Major Abdominal Surgeries
Effect of PCO2 Gap Algorithm Application on Outcome of High Risk Surgical Patients Undergoing Major Abdominal Surgeries
1. Primary (main): Comparison between goal directed therapy and PCO2 gap algorithm (carbon dioxide partial pressure venous arterial gap algorithm) application on 30 days mortality and organ dysfunction post operative 2.
- Trial name
- NCT04792242
- Testing
- cv line insertion, Urinary catheter insertion, Arterial line
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- South Valley University
Elective Major Abdominal Surgery
Lidocaine Infusion for Major Abdominal Pediatric Surgery
In this study, the investigators hypothesized that perioperative i.v. infusion of lidocaine in major abdominal pediatric surgery, may have a beneficial effect on hemodynamic and hormonal responses.
- Trial name
- NCT01387568
- Testing
- Lidocaine Infusion, saline Infusion
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Intra-abdominal Perforation
the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations
This prospective intended to observe the influence of prophylactic and empirical anti-fungal treatment on Severe Sepsis patients with perforations.
- Trial name
- NCT02941068
- Testing
- fluconazole and caspofungin
- Volunteers
- 223 people
- Sponsor
- Nanjing PLA General Hospital
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Major Abdominal Surgeries
Effect of Intrathecal Morphine in Children Undergoing Major Abdominal Surgeries,
safety and efficacy of intrathecal morphine in post operative pain relief in pediatric patients undergoing major abdominal cancer surgeries using different doses of intrathecal morphine (2 μg/kg , 5 μg/kg ,10 μg/kg).
- Trial name
- NCT03158584
- Testing
- Intrathecal Morphine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Assiut University
First-attempt Success Rate of Real-time Ultrasound-guided Thoracic Epidural Catheter Placement
Application of Real-time Ultrasound Guidance in Thoracic Epidural Catheter Placement
The goal of this clinical trial is to assess the success rate of real-time ultrasound-guided thoracic epidural catheter placement at the first attempt in patients who will undergo thoracic or abdominal surgeries.
- Trial name
- NCT07100769
- Testing
- Real-time ultrasound-guided thoracic epidural placement
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Colectomy, Pancreatectomy
Implementation of a GDT Algorithm for Major Surgery Patients
This study examines the effect of an algorithm for GDT for patients undergoing major surgery under routine conditions.
- Conditions
- Colectomy, Pancreatectomy, Fluid Therapy
- Trial name
- NCT02509910
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Philipps University Marburg
Surgery, Complications, Postoperative
Effects of Prone Position After Major Abdominal Surgery
Evaluation of postoperative prone position after major abdominal surgery. A randomized clinical trial of 100+100 patients and further add a voice/speech/singing protocol.
- Conditions
- Surgery, Complications, Postoperative, Lung Infection
- Trial name
- EPOS (NCT05630443)
- Testing
- prone position
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Abdominal Cancer
Safety and Efficacy of Intrathecal Morphine in Children
Postoperative pain in pediatrics can usually be well controlled with a combination of analgesics including acetaminophen ( paracetamol) ,NSIADS, opioids , and local/regional anesthesia.The use of epidural and subarachnoid…
- Trial name
- NCT03120403
- Testing
- intrathecal morphine
- Volunteers
- 45 people
- Sponsor
- Alaa Ali Mohamed Elzohry
Acute Kidney Injury
Acute Kidney Injury in Major Abdominal Surgery: Retrospective Study of 501 Patients
Retrospective study that aims to examine the presence of acute kidney injury (AKI) during major abdominal surgery, non- cardiac surgery. Using clinical and biochemical data in order to establish AKI frequency and risk factors.
- Trial name
- NCT04130347
- Volunteers
- 499 people
- Sponsor
- Uppsala University