Clinical trials: MRI Sedation
Respiratory Morbidity
Dexmedetomidine Sedation in Children With Respiratory Morbidities
This study aimed to determine the feasibility of dexmedetomidine in children with respiratory morbidities who required deep sedation for magnetic resonance imaging (MRI) scans.
- Trial name
- NCT02555605
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Universitair Ziekenhuis Brussel
Autism Spectrum Disorder, Dexmedetomidine
Esketamine Combined With Dexmedetomidine Sedation in Head MRI Examination of Children With Autism Spectrum Disorder
Objective: To investigate the use of ketamine combined with dexmedetomidine for sedation in children with autism spectrum disorder, Methods:aged 2-6 years,, ASA grade I or II.
- Conditions
- Autism Spectrum Disorder, Dexmedetomidine, Esketamine, Sedation
- Trial name
- NCT06633315
- Testing
- low dos dexmedetomidine, high dos dexmedetomidine, dexmedetomidine and esketamine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Sedation for Children Undergoing MRI
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: will receive oral Melatonin and nasal Sevoflurane.
- Trial name
- NCT06606899
- Testing
- Melatonin 3 MG, Chloral Hydrate, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Procedural Sedation, EEG
Factors Associated With Successful Completion of MRI in Children Undergoing a Vigil Sedation With Dexmedetomidin
This is a retrospective cohort study aiming to determine whether the use of Dexmedetomidine (DEX) to sedate children prior to MRI scanning is more or less effective in children with autism spectrum disorders or other…
- Conditions
- Procedural Sedation, EEG, MRI
- Trial name
- RIDEX (NCT06203522)
- Testing
- Data collection of successful completion of MRI
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Magnetic Resonance Imaging Contrast Media Adverse Reaction, Sedation Complication
Non-operating Room Anesthesia Experiences in Pediatric Magnetic Resonance Imaging Cases
In recent years, out patient anesthesia applications have been increasing for diagnostic and interventional procedures for pediatric patients.
- Trial name
- NCT05423821
- Testing
- Anesthesia efficacy in patients undergoing MRI
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Yunus Emre
Complications
Thiopental Versus Propofol During Magnetic Resonance Imagining in Children: Something Old, Something New
Magnetic resonance imagining (MRI) in children requires sedation to achieve the degree of cooperation or immobilization, necessary to complete these procedures successfully.
- Trial name
- NCT01318044
- Testing
- Propofol and Thiopental
- Where
- Albania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinical Centre of Kosova
Pediatric Sedation
Lullaby vs White Noise vs Silence in Pediatric MRI Sedation
This prospective randomized study aims to evaluate the effects of three auditory conditions-lullaby music, white noise, and silent headphone use-on sedation depth, anesthetic drug requirements, and recovery outcomes in children…
- Trial name
- CALMMRI (NCT07325331)
- Testing
- Silent Headphone, White Noise, Lullaby Music
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Seizures, Development Delay
Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years
The investigators aim to identify the frequency with which an elective brain MRI yields and etiologic diagnosis to explain its indication.
- Conditions
- Seizures, Development Delay, Anesthetic Neurotoxicity
- Trial name
- NCT03561168
- Testing
- Change in plan of care based on MRI results
- Where
- United States
- Volunteers
- 561 people
- Sponsor
- Baylor College of Medicine
Neurological Disorders
Comparison of the Effectiveness of CAM Therapies in Pediatric Patients Undergoing Sedation
The investigators conducted a prospective open unblinded clinical four-arm evaluation of Complementary and Alternate Medicine (CAM) interventions on children 1-12 years of age who were undergoing imaging by Medical Resonance…
- Trial name
- NCT01858350
- Testing
- Active Music Therapy, Passive Music Therapy, Distraction Therapy
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Wayne State University
Procedural Sedation and Analgesia, Pediatric ALL
Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring
This is a prospective, monocentric diagnostic study aiming to evaluate whether a sedation score obtained by a per-procedural electroencephalogram (EEG), the PSI score, could identify patients for whom a 2 μg/kg dose of DEX would…
- Trial name
- DINAMO (NCT06867289)
- Testing
- EEG
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
MRI Sedation
The Pharmacokinetics of Dexmedetomidine in Children
This study is designed to identify the plasma concentrations which are required to achieve adequate sedation, using a Ramsay Sedation Scale.
- Trial name
- NCT00909935
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Children's Hospital
Children Requiring Sedation for MRI/CT
The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Prospective Study
Sedation and anesthesia for which to perform diagnostic imaging represents a rapidly growing field of practice, especially in children. Propofol is the most common sedative drug administered for MRI/CT.
- Trial name
- NCT01855555
- Testing
- sedation with propofol
- Where
- South Korea
- Volunteers
- 2,948 people
- Sponsor
- Yonsei University
Mental Health, Anxiety
Anxiety in Children and Families During MRI Under Anesthesia
This prospective randomized controlled study evaluates the impact of age-appropriate therapeutic play and structured parental briefing on perioperative anxiety during pediatric MRI under sedation.
- Trial name
- NCT07693309
- Testing
- Multi-modal Psychological Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Afyonkarahisar Health Sciences University
Airway Remodeling
Airway Dimension Study in Children Undergoing MRI Sedated With Propofol and Dexmedetomidine
Sedation is required in infants and children to successfully complete MRI while maintaining respiratory and hemodynamic stability. Limited access to the patient may pose a safety risk during MRI examination.
- Trial name
- NCT01505933
- Testing
- Dexmedetomidine, propofol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Milton S. Hershey Medical Center
Headache, Tumor
Dexmedetomidine and Propofol for Pediatric MRI Sedation
The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia…
- Conditions
- Headache, Tumor, Seizure Disorder, Neurofibromatoses
- Trial name
- NCT03513757
- Testing
- propofol, Dexmedetomidine, Glycopyrrolate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Magnetic Resonance Imaging
Dexmedetomidine and Ketamine in MRI
The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and ketamine, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults.
- Trial name
- NCT02652507
- Testing
- Dexmedetomidine, Ketamine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Magnetic Resonance Imaging
Prospective Study Assessing the Validity of Y-PAS (Yale Preoperative Anxiety Scale) to Predict Patients Undergoing Magnetic Resonance Imaging Without the Use of Sedation/General Anesthesia
The mYPAS (Modified Yale Preoperative Anxiety Scale) is a quick, easy, validated and "gold standard" assessment tool to measure pediatric anxiety in the perioperative period.
- Trial name
- NCT02586103
- Testing
- MRI simulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Arlyne Thung
Safety and Efficacy of Sedation Medications
Comparing Safety and Efficacy of Dexmedetomidine and Propofol
This is a prospective, open label randomized study. The purpose of this study is to compare propofol with dexmedetomidine for pediatric monitored anesthesia care for MRI, specifically identifying important patient demographics…
- Trial name
- NCT01152021
- Testing
- Dexmedetomidine, Propofol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
MRI, Pediatric Sedation
Intranasal Dexmedetomidine Versus Oral Midazolam as Premedication for Propofol Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging
A magnetic resonance imaging (MRI) examination usually takes 30 to 45 minutes and requires the patient to remain perfectly still during the entire acquisition process to ensure quality.
- Conditions
- MRI, Pediatric Sedation, Midazolam, Dexmedetomidine
- Trial name
- NCT05192629
- Testing
- Dexmedetomidine, Midazolam
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Brugmann University Hospital
Epilepsy, Cerebral Palsy
A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
This is a pilot study to determine if a standard bolus dose and infusion of dexmedetomidine can significantly decrease the dose of propofol (infusion) required for accomplishing an MRI.
- Conditions
- Epilepsy, Cerebral Palsy, Developmental Delay
- Trial name
- NCT02633241
- Testing
- Dexmedetomidine bolus and high infusion-Propofol, Dexmedetomidine bolus and low infusion-Propofol, Dexmedetomidine bolus only - Propofol
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Joseph Cravero