Clinical trials: Lymph Node Cancer
Surgery-Complications
Factors Affecting the Difficulty of Laparoscopic D2 Lymph Node Dissection for Gastric Cancer
Laparoscopic D2 lymph node dissection (LND) for gastric cancer has a wide range of operations and a high degree of difficulty.The purpose of this study was to evaluate the relationship between clinicopathological factors and the…
- Trial name
- NCT05585073
- Testing
- Whether lymph node dissection is qualified or not
- Where
- China
- Volunteers
- 187 people
- Sponsor
- Fujian Medical University
Stage I Adrenal Cortical Carcinoma AJCC v7, Stage II Adrenal Cortical Carcinoma AJCC v7
Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor
This phase III clinical trial is studying how well cisplatin-based chemotherapy and/or surgery works in treating young patients with stage I, stage II, stage III or stage IV adrenocortical cancer.
- Conditions
- Stage I Adrenal Cortical Carcinoma AJCC v7, Stage II Adrenal Cortical Carcinoma AJCC v7, Stage III Adrenal Cortical Carcinoma AJCC v7, Stage IV Adrenal Cortical Carcinoma AJCC v7
- Trial name
- NCT00304070
- Testing
- Cisplatin, Conventional Surgery, Doxorubicin Hydrochloride
- Where
- 91 sites in United States, Australia and 2 more
- Volunteers
- 78 people
- Sponsor
- Children's Oncology Group
Neuroendocrine Tumors, Small Intestinal NET
Preoperative Imaging in Patients With Small Bowel Neuroendocrine Tumors
Digestive NETs are the second most common malignant digestive tumor after adenocarcinoma. The most common gastrointestinal NETs arise from the small intestine.
- Conditions
- Neuroendocrine Tumors, Small Intestinal NET, Lymph Node Metastasis
- Trial name
- TEGRELE (NCT05246319)
- Testing
- preoperative imaging
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Laurent BRUNAUD
Lung Neoplasms, Lymph Node Excision
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules.
- Trial name
- NCT04631770
- Testing
- Systemic mediastinal lymph node dissection, Spared mediastinal lymph node dissection
- Where
- China
- Volunteers
- 1,362 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Thyroid Cancer, Lymph Node Metastasis
The Usefulness of Staining Lymph Nodes During Operations for Cancer Thyroid in Detecting the Nodes That Have Cancer
Detection of lymph nodes starting to be involved by cancer spreading from the thyroid gland during operation is useful. It saves the patient from having a second operation to remove these nodes later on when they become obvious.
- Trial name
- NCT00794053
- Testing
- detecting lymph node metastasis by staining
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- University of Alexandria
Breast Cancer
Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen.
- Trial name
- NCT00002646
- Testing
- fenretinide, tamoxifen citrate
- Where
- 85 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Eastern Cooperative Oncology Group
Early Gastric Cancer
Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection for Early Gastric Cancer
The purpose of this study is to determine whether Endoscopic Submucosal Dissection combine with Laparoscopic Regional Lymph node Dissection for early gastric cancer can improve Disease-free survival ？
- Trial name
- NCT02325999
- Testing
- ESD AND LRLD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Early Gastric Cancer
Short-term Outcomes of Laparoscopic Versus Open Gastrectomy With Lymph Node Dissection for Early Gastric Cancer :a Randomized Controlled Study
While the incidence of gastric cancer is gradually declining, it is the fifth most common cancer worldwide and the third most common cause of cancer related death worldwide according to GLOBOCAN 2018 data (Rawla P and Barsouk…
- Trial name
- NCT05707338
- Testing
- Gastrectomy with lymph node dissection
- Volunteers
- 40 people
- Sponsor
- Sohag University
Gastric Cancer, Sentinel Lymph Node
Fluorescence Image-Guided Lymphadenectomy in Robotic Gastrectomy
Gastric cancer is a worldwide challenge due to its spread, even epidemic in some areas, and the high mortality rates. Lymphadenectomy is considered the fundamental step during radical gastrectomy.
- Trial name
- IG-MIG (NCT03931044)
- Testing
- Image-Guided Robotic Gastrectomy
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- International Study Group on Minimally Invasive Surgery for Gastric Cancer
Stage IA Skin Melanoma, Stage IB Skin Melanoma
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma
This pilot clinical trial studies recombinant interferon alfa-2b in treating patients with melanoma. Recombinant interferon alfa-2b may interfere with the growth of tumor cells and slow the growth of melanoma
- Conditions
- Stage IA Skin Melanoma, Stage IB Skin Melanoma, Stage IIA Skin Melanoma, Stage IIB Skin Melanoma
- Trial name
- NCT01460875
- Testing
- recombinant interferon alfa-2b, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- William Carson
Breast Cancer Stage III
Clinical Significance of Supraclavicular Lymph Node Dissection for Breast Cancer
Breast cancer patients with ipsilateral supraclavicular lymph node metastasis are defined as Ⅲc stage (N3) according to the newly published 8th AJCC TNM staging system. No concret guide line was supported to such patients.
- Trial name
- NCT03716245
- Testing
- supraclavicular lymph node dissection, supraclavicular area radiotherapy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xinhong Wu, PhD
Gastric Cancer, Sentinel Lymph Node
Gastric Cancer Sentinel Lymph Node Mapping
Gastric cancer has an incidence in North America of over 24,000 new cases annually, of which approximately 15% are diagnosed at an early stage.
- Conditions
- Gastric Cancer, Sentinel Lymph Node, Early Gastric Cancer
- Trial name
- NCT03049345
- Testing
- Sentinel Lymph Node Sampling, Radioactive Tracers, Methylene Blue 20 MG/ML
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Recurrence, Breast Cancer
Sentinel Node Biopsy in Breast Cancer Patients
Axillary lymph node dissection (ALND) was previously the standard axillary staging procedure in breast cancer patients. However, ALND is accompanied by a considerable morbidity, and sentinel lymph node biopsy (SLNB) evolved as a…
- Trial name
- NCT01351974
- Where
- Sweden
- Volunteers
- 3,369 people
- Sponsor
- Uppsala University
Lymphocele, Prostate Cancer
Microspheres in Preventing Lymphatic Fluid Collection After Surgery in Patients With Prostate Cancer
This study is being performed to investigate if the application of Arista absorbable hemostat (AH)®, a product approved to stop surgical bleeding, can prevent lymphoceles.
- Trial name
- NCT01644136
- Testing
- robot-assisted laparoscopic surgery, regional lymph node dissection, microsphere-mediated lymphocele prevention
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Injection Methods in Finding the Sentinel Lymph Node During Lymphatic Mapping and Sentinel Lymph Node Biopsy in Patients With Invasive Breast Cancer
RATIONALE: Diagnostic procedures, such as lymphoscintigraphy using an injection under the nipple or near the tumor, may help doctors find out how far the disease has spread.
- Trial name
- NCT00438477
- Testing
- Isosulfan Blue, Lymphangiography, Technetium Tc 99m sulfur colloid
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
New Approaches for the Identification and Characterization of Functional Markers of the Risk of Extension of Breast Cancer Without Lymph Node Involvement
1. Identify the tissue proteins associated with early breast cancer invasion phases without lymph node involvement . 2. Consider their role in the invasion and the risk of tumor spread .
- Trial name
- NCT02926547
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Vulvar Cancer
Radiation Therapy or Surgery in Treating Patients With Previously Untreated Vulva Cancer With Positive Groin Lymph Nodes
RATIONALE: Patient abstract not available PURPOSE: Patient abstract not available
- Trial name
- NCT00898352
- Testing
- regional lymph node dissection, radiation therapy
- Sponsor
- Gynecologic Oncology Group
Gastric Neoplasm
Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)
To compare left thoraco-abdominal approach with abdominal and transhiatal approach to cardia or subcardia cancer
- Trial name
- NCT00149266
- Testing
- Surgery: abdominal and transhiatal approach, Surgery: left thoraco-abdominal approach
- Where
- Japan
- Volunteers
- 167 people
- Sponsor
- Japan Clinical Oncology Group
Prostate Cancer
Neoadjuvant Hormones + Docetaxel in Node-Positive Prostate Cancer
The goal of this clinical research study is to find out if a therapy using docetaxel chemotherapy with hormonal therapy taken before your scheduled surgery is beneficial to treatment of prostate cancer.
- Trial name
- NCT01076335
- Testing
- Neoadjuvant Hormonal Therapy, Docetaxel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Wilms Tumor
Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation
Participants are being asked to take part in this clinical trial, a type of research study, because the participants have a Wilms Tumor cancer.
- Trial name
- NCT04968990
- Testing
- Proton Beam Radiation (PBRT), DD-4A Chemotherapy Regimen, Complete Surgical Resection
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- St. Jude Children's Research Hospital