Clinical trials: Lumbar Disc Disease
Low Back Pain
The Effect Of Low Back Pain on Paraspinal Muscles
Low back pain is frequently seen in the adolescent age group, with a prevalence approaching that of the adult age group. The most common type is non-specific, self-limiting low back pain.
- Trial name
- NCT04555356
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Degenerative Disc Disease, Spinal Stenosis
Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable Screws
Trinica Anterior Lumbar Plate (ALP) System is a commercially available, supplemental fusion device for use in the lumbar or sacral spine (L1-S1) to treat instability.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT00762723
- Testing
- Trinica Anterior Lumbar Plate System
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Zimmer Biomet
Spondylolisthesis, Intervertebral Disc Degeneration
Clinical Evidence of Robot Guided vs. Navigated vs. Free Hand Lumbar Spinal Fusion
Computer-based navigation systems were first introduced to spine surgery in 1995 and while they have been long established as standards in certain cranial procedures, they have not been similarly adopted in spine surgery.
- Trial name
- NCT02998060
- Testing
- Pedicle Screw Placement, SpineAssist®/Renaissance® (Mazor Robotics Ltd. Caesarea, Israel), 3D C-Arm (Ziehm Imaging, Nuremberg, Germany)
- Where
- 2 sites in Germany, Switzerland
- Sponsor
- Marc Schröder
Degenerative Disc Disease, Pain
Efficacy of Intradiscal Injection of Viable Placental Tissue Extract in Subjects With One or Two Level, Symptomatic Lumbar Intervertebral Disc Degeneration
Dr. Parker (the "Investigator") and Semmes Murphey Foundation ("Foundation") are conducting a study of outcomes and safety associated with degenerative discs at Semmes-Murphey Clinic, P.C. ("Semmes-Murphey").
- Trial name
- NCT02379689
- Testing
- Injectable placental tissue extract called BioDGenesis (Active Product)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Semmes-Murphey Foundation
Degenerative Disc Disease Lumbar, Spinal Stenosis
Multimodal Analgesia Versus Routine Care Pain Management
Most patients undergoing surgery experience significant post-operative pain. Inadequate peri-operative pain management may decrease post-operative mobilization and increase length of hospitalization.
- Conditions
- Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- MMA (NCT01861743)
- Testing
- Multimodal Analgesia, Patient controlled analgesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Recurrent Lumbar Disc Herniation
The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach
What Was the Study About? This study focused on improving the care of patients with a specific type of back problem called lumbar disc herniation at the L5-S1 level.
- Trial name
- NCT06833099
- Testing
- VAS Point and Imaging Examination
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Jinyu Chen
Degenerative Spine, Degeneration of Lumbar Intervertebral Disc
Percutaneous Trans-facet Spine Fixation
Percutaneous Trans-facet Fixation Massoud-Goel Technique and Theory for Treatment of Degenerative Spine
- Conditions
- Degenerative Spine, Degeneration of Lumbar Intervertebral Disc, Degenerative Cervical Disc Disease, Ligamentum Flavum Hypertrophy
- Trial name
- Massoud-Goel (NCT07001969)
- Testing
- Massoud-Goel Technique and Theory, Percutaneous Trans-facet Fixation for Treatment of Degenerative Spine
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Mahmoud Massoud
Degenerative Disc Disease, Spondylolisthesis
Evaluation of NB1 Bone Graft Following Lumbar Interbody Arthrodesis
The objective of this clinical study is to evaluate the safety and effectiveness of NB1 Bone Graft in subjects with degenerative disc disease undergoing transforaminal lumbar interbody fusion.
- Trial name
- NCT03810573
- Testing
- NB1
- Where
- 2 sites in Australia
- Volunteers
- 30 people
- Sponsor
- Bone Biologics Corp
Lumbar Disc Herniation
Evaluation of Interbody Cage Insertion in Treatment of Lumbar Disc Prolapse
Comparison between discectomy alone and interbody cage insertion in treatment of lumbar disc prolapse
- Trial name
- NCT04083703
- Testing
- Interbody cage insertion in lumbar disc prolapse
- Volunteers
- 2 people
- Sponsor
- Assiut University
Degenerative Disc Disease, Spondylolisthesis
Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion
This study is undertaken to evaluate the outcomes of Oblique Lateral Lumbar Interbody Fusion (OLLIF). Specifically, the study seeks to measure outcomes on radiological imaging, outcomes reported by the patients on standardized…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT03726190
- Testing
- Oblique Lateral Lumbar Fusion
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Tristate Brain and Spine Institute
Degenerative Disc Disease
CHARITE™ vs. ALIF 5-Year Follow-up
To assess the clinical and radiographic outcomes through 5-years following treatment with CHARITÉ™ Artificial Disc vs. the BAK Cage for treatment of degenerative disc disease at one level (L4-S1).
- Trial name
- NCT00215332
- Testing
- CHARITE
- Where
- 10 sites in United States
- Volunteers
- 367 people
- Sponsor
- DePuy Spine
Lumbar Herniated Disc
US-MR Image Fusion-guided Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc Herniation
The purpose of this study is to evaluate the feasibility and efficacy of US-MR image fusion-guided percutaneous transforaminal endoscopic discectomy for the treatment of lumbar disc herniation
- Trial name
- NCT03403244
- Testing
- US-MR image fusion-guided PTED, fluoroscopy-guided PTED
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Lumbar Disc Herniation
Effect of PNF and Lumbar Stabilization Exercises on Muscle Strength and Endurance in Lumbar Disc Hernia
Background/Objective: This study investigates the effect of lumbar stabilization and proprioceptive neuromuscular facilitation (PNF) training on muscle strength and muscle endurance.
- Trial name
- PNF (NCT03651440)
- Testing
- PNF, lumbar stabilization training, Physical Therapy
- Volunteers
- 64 people
- Sponsor
- Baskent University
Lumbar Intervertebral Disc Herniation
A Randomized Trial of Annular Repair With Discectomy Versus Discectomy Alone for Lumbar Disc Herniation
The goal of this study is to explore the indications and application scope of spinal endoscopy combined with annulus fibrosus repair technology, with a focus on verifying the effectiveness of annulus fibrosus suture technology…
- Trial name
- NCT07250581
- Testing
- Repair of the annulus fibrosus
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Lumbar Disc Herniation
Efficacy of Navigable Percutaneous Plasma Disc Decompression Device (L'DISQ) in Patients With Severe Lumbar Disc Herniation
This study aims to assess the clinical outcome of percutaneous disc decompression using the L'DISQ in patients with severe lumbar disc herniation (LDH).
- Trial name
- L'DISQ (NCT05231759)
- Testing
- L'DISQ
- Volunteers
- 30 people
- Sponsor
- Korea University Anam Hospital
Pain
Blood Sample Donations to Study the Role of Genes in Pain
This study attempts to identify genes that may increase or decrease the likelihood of sciatic pain (shooting pain down the leg) persisting 1 year after treatment of a herniated spinal disc.
- Trial name
- NCT00341367
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
To Evaluate the Effect of Exercise With Virtual Glasses on Pain, Activities of Daily Living and Quality of Life
Individuals With Lumbar Disc Hernia Exercising With Virtual Reality Glasses
The purpose of this research; exercise performed with virtual reality glasses for individuals with lumbar disc herniation; The aim of this study is to examine the effects on pain, activities of daily living, quality of life and…
- Trial name
- NCT05463588
- Testing
- Exercising with virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ataturk University
Stenosis, Herniated Nucleus Pulposus
Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion
Neural injury is a well-known complication following extreme lateral lumbar interbody fusion (XLIF). It has been found that up to 9.4% of patients will have either temporary or persistent neurologic deficit.
- Conditions
- Stenosis, Herniated Nucleus Pulposus, Degenerative Disc Disease, Spondylosis
- Trial name
- NCT03327272
- Testing
- Methylprednisolone, Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Degenerative Disc Disease, Spondylolisthesis
Retest-reliability and At-home-assessment Feasibility of the 5R-STS
The five-repetition sit-to-stand test has been validated and is used primarily in pulmonary medicine and cardiology, and has recently been shown to be a useful tool for the objective assessment of functional impairment in…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- 5RSTS-2 (NCT03321357)
- Testing
- five-repetition sit-to-stand test
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Bergman Clinics