Clinical trials: Low Blood Pressure
Hypotension
Influence of Injection Rate of Intrathecal Mixture of Local Anesthesia on Hypotension in Cesarean Section
Hypotension is the most common complication of neuraxial anesthesia in obstetric patients and its prevalence in cesarean section is about 50-90%.
- Trial name
- NCT03517683
- Testing
- Low speed, High speed
- Where
- Lebanon
- Volunteers
- 159 people
- Sponsor
- Makassed General Hospital
1. VLBW Infants, 2. Hypotension
Neurological Outcome of VLBW Infants With Early Hypotension
Comparison of short and long term neurological outcome of VLBW infants with and without early onset hypotension required intervention.
- Trial name
- NCT00266422
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
Multi-system Atrophy - Parkinsonian Type, Orthostatic Hypotension, Dysautonomic
Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease.
This study is aimed at patients with multi-system atrophy - parkinsonian type (P-MSA) or Parkinson's disease (PD) receiving dopaminergic drugs and suffering from orthostatic hypotension (OH).
- Conditions
- Multi-system Atrophy - Parkinsonian Type, Orthostatic Hypotension, Dysautonomic, Parkinson Disease
- Trial name
- CARBIDOH (NCT06831500)
- Testing
- Administration of Carbidopa/levodopa
- Where
- 2 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Julien Bally
Hypotension, Shock
Optimal VAsopressor titraTION Pilot Randomized Controlled Trial
The purpose of this research study is to determine if it is better to give vasopressors to patients to maintain a higher blood pressure target versus a lower blood pressure target.
- Trial name
- OVATION (NCT01800877)
- Testing
- Vasopressors
- Where
- 10 sites in United States, Canada
- Volunteers
- 120 people
- Sponsor
- Francois Lamontagne
Spinal Cord Injuries, Orthostatic Hypotension
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
This study seeks to evaluate whether the speed (cadence) of lower extremity robotic movement has an impact on orthostatic hypotension and upright tolerance when training with the ErigoPro robotic tilt-stepper.
- Trial name
- NCT04029974
- Testing
- ErigoPro
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Methodist Rehabilitation Center
Hypotension, Cesarean Section
Comparison of Hypotension During Spinal Anaesthesia for C-section
Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.
- Conditions
- Hypotension, Cesarean Section, Aortocaval Compression
- Trial name
- NCT05427968
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Rawalpindi Medical College
Asthma, Obesity
Reducing Socioeconomic Disparities in Health at Pediatric Visits
This research project is aimed to assess the effectiveness and impact of a pediatric-based intervention aimed at reducing low-income families' unmet material needs (food, housing, employment, childcare, household heat, education…
- Conditions
- Asthma, Obesity, Health Care Utilization, Health Care Disparities
- Trial name
- WECARE01 (NCT02451059)
- Testing
- WE CARE survey, WE CARE Community Resource Handout, Patient Navigator
- Where
- 6 sites in United States
- Volunteers
- 1,205 people
- Sponsor
- Boston Medical Center
Hypertension
Impact of Citrulline and Arginine Supplementation on the Post-exercise Hypotension (PEH)
Post-exercise hypotension (PEH) is a established phenomenon as one of the non-pharmacological ways of reducing blood pressure, producing important impacts, particularly in hypertensive individuals.
- Trial name
- PEH (NCT03378596)
- Testing
- L-citrulline + L-arginine, L-arginine, L-citrulline
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Juliano Casonatto
Hypotension
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, ≥12 to 16 year old patients…
- Trial name
- NCT02323399
- Testing
- Phenylephrine
- Where
- 10 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West-Ward Pharmaceutical
Anesthesia, Pediatrics
Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy
This study aims to assess the efficacy and safety of prophylactic intraoperative norepinephrine infusion versus the standard technique on decreasing the incidence of intraoperative hypotension in infants undergoing Kasai…
- Conditions
- Anesthesia, Pediatrics, Biliary Atresia
- Trial name
- NCT05521152
- Testing
- Norepinephrine Bitartrate
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Kasr El Aini Hospital
Maternal Hypotension Syndrome, Cesarean
Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section
Spinal anesthesia is still the gold standard anesthetic method for elective and urgent cesarean section, the post spinal hypotension remains the most frequent complication of this procedure and is still responsible of…
- Trial name
- NCT03719625
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Renal Dialysis
The Effect of Food Intake During Hemodialysis on Blood Pressure
Intradialytic hypotension is one of the most common complications associated with food intake during hemodialysis. Whether patients should be allowed to eat during hemodialysis is still a moot point.
- Trial name
- NCT05405348
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- melek avcı
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Parkinson Disease, MSA - Multiple System Atrophy
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease
Clinical diagnosis of Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) is challenging, especially in the early stages.
- Conditions
- Parkinson Disease, MSA - Multiple System Atrophy, Lewy Body Dementia (LBD), Neurodegenerative Disease
- Trial name
- EXTRAORDINARY (NCT06846658)
- Where
- 3 sites in Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Breastfeeding, Hypertension
Does Breastfeeding Lower Blood Pressure in Postpartum Hypertensive Patients
The primary aim is to establish whether breastfeeding is associated with lowering blood pressure in hypertensive women.
- Trial name
- NCT02574494
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Hypotension and Shock
Role of Low Dose Epinephrine Boluses In Acute Hypotension
The Study evaluates the role of low dose epinephrine boluses in management of acute hypo-tension VS The Traditional management of acute hypo-tension.
- Trial name
- NCT03671070
- Testing
- Epinephrine, Traditional management of shock
- Volunteers
- 50 people
- Sponsor
- Assiut University
Liver Resection
A Trial to Compare Pringle Maneuver With Either Infrahepatic Inferior Vena Cava Clamping or Low Central Venous Pressure
The purpose of this study is to better comprehend the benefits and efficacy of portal triad clamping with infrahepatic IVC clamping during complex hepatectomy.
- Trial name
- NCT01355887
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Huazhong University of Science and Technology
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Fever, Orthostatic Hypotension
Orthostatic Hypotension in Children With Acute Febrile Illness
Objective:to determent if children suffering from acute febrile illness has higher rate of orthostatic hypotension compared with children with no febrile illness. Design: a prospective cohort study.
- Trial name
- NCT00452712
- Testing
- All subjects will have their blood pressure measured in supine position (after 5 minute of rest) and after 3 minute of standing.
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Infant, Premature, Hypoperfusion in Newborn
Monitoring of Systemic or Organ Perfusion for Preterm Infants
To investigate biomarker reflects systemic or specific organ perfusion well, we are going to the observational comparison study using several hemodynamic monitoring methods in the premature infants.
- Conditions
- Infant, Premature, Hypoperfusion in Newborn, Necrotizing Enterocolitis of Newborn, Sepsis Newborn
- Trial name
- NCT03136172
- Testing
- NIRS (near Infra-red spectroscopy)
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Inha University Hospital