Clinical trials: Local Anesthesia Infiltration
Local Anesthetic Complication
The Effect of Adding Sodium Bicarbonate 8.4% to Local Anesthesia on Pain During Upper Canine Infiltration
The aim of the present study was to evaluate the pain during local anesthetic buccal infiltration for the maxillary canines after adding Sodium Bicarbonate 8.4% during local anesthesia.
- Trial name
- NCT06302907
- Testing
- Buffered Local anaesthesia, Unbuffered Local anaesthesia
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Wataniya University
Anesthesia, Local
Comparison Between Efficiency of Inferior Alveolar Nerve Block and Buccal Infiltration Techniques Using Articaine 4% 1:100000
This split mouth randomized control trial is designed as to compare the effectiveness of the buccal infiltration technique with the gold standard inferior alveolar nerve block in anesthetizing mandibular second primary molars to…
- Trial name
- NCT03130855
- Testing
- inferior alveolar nerve block with 4% articaine, buccal infiltration with 4% articaine
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Pain, Anesthesia, Local
Self-Reported Pain in Children Submitted to Single Infiltration of Articaine During Primary Molar Extraction
The aim of this study is to analyze the effectiveness of articaine in controlling self-reported pain compared with conventional lidocaine anesthesia in children requiring extraction of deciduous maxillary molars.
- Trial name
- NCT05443009
- Testing
- Lidocaine, Articaine
- Where
- 4 sites in Brazil
- Volunteers
- 76 people
- Sponsor
- Universidade Federal de Santa Catarina
Dental Anxiety, Dental Fear
Virtual Reality Distraction During Dental Local Anesthesia Among Children
To evaluate the effect of virtual reality (VR) distraction on anxiety and pain during buccal infiltration anesthesia (BIA) in pediatric patients.
- Trial name
- NCT04483336
- Testing
- Virtual Reality Distraction, TV Screen Distraction
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Abdulaziz University
Laparoscopic Cholecystectomy Surgery, Analgeisa
Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration
Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain…
- Conditions
- Laparoscopic Cholecystectomy Surgery, Analgeisa, Local Anesthetic Infiltration
- Trial name
- NCT07409688
- Testing
- Intraoperitoneal local anesthetic administration, Sub cutaneous administration of local anesthetic
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Adductor Canal Block, Postoperative Pain
Comparison of Combination of Proximal ACB and iPACK With Large-Volume Distal ACB for Early Mobilization After TKR
Large-volume distal ACB is not superior to combination of proximal ACB and iPACK in facilitating early mobilization after TKR. Block performing time of distal ACB was significantly shorter compared to the combination of proximal…
- Conditions
- Adductor Canal Block, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT06525493
- Testing
- Regional Anesthesia
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Ropivacaine, Laparoscopic Cholecystectomy
Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain
Pain still remains a limiting factor in early discharge of patients undergoing laparoscopic cholecystectomy. Almost all earlier studies done to compare the efficacy of local anaesthetics used intraperitoneally as compared to…
- Conditions
- Ropivacaine, Laparoscopic Cholecystectomy, Pain
- Trial name
- NCT03265223
- Testing
- 0.2% ropivacaine
- Volunteers
- 353 people
- Sponsor
- Jawaharlal Nehru Medical College
Anesthesia, Local
Articaine Infiltration in Anesthetizing Mandibular Second Primary Molars
Background: Articaine hydrochloride has steadily grown in popularity, and studies have shown that articaine hydrochloride performs better than lidocaine due to an enhanced anes-thetic efficacy.
- Trial name
- NCT06201949
- Testing
- Articaine infiltration technique, Articaine nerve block technique
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Hams Hamed Abdelrahman
Hypothalamic Neoplasms, Pituitary Diseases
The Cardiovascular Changes Associated With Septal Local Anaesthesia
The purpose of this study is to determine the effects on the heart of injecting local anaesthetic into the nose prior to surgery on the pituitary gland?
- Conditions
- Hypothalamic Neoplasms, Pituitary Diseases, Anesthesia, Local
- Trial name
- NCT03137615
- Testing
- Pituitary surgery, local anaesthetic injection
- Volunteers
- 15 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Appendicitis
A Comparison of UGBRS Block and Local Infiltration
In this research study, the investigators are trying to find out which of the two methods of injecting local anesthetics (at the site of the belly button cut or by ultrasound guided rectus sheath block) will provide better pain…
- Trial name
- NCT02352519
- Testing
- UGBRSB, Local Infiltration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Anesthesia
Needle-Free Lidocaine Injection vs Traditional Local Anesthesia in Infant Lumbar Puncture
We hypothesize that the J-Tip needle-free jet-injection system offers comparable pain control and greater provider satisfaction due to its less invasive nature compared to traditional needle infiltration of 1% lidocaine in…
- Trial name
- NCT06552351
- Testing
- Needle-Free Jet Injection of 1 % lidocaine, traditional needle infiltration of 1% lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anesthesia, Caudal
Caudal Block Versus Local Wound Infiltration for Inguinal Procedures
Single-centre observational study to analyse whether there is a difference in post-operative pain scores and set up time when comparing caudal block with local wound infiltration
- Trial name
- NCT04590027
- Volunteers
- 86 people
- Sponsor
- University Hospital Tuebingen
Anesthesia, Local
Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications
This Randomized study was designed to assess and compare the effect of two analgesic premedications (Ibuprofen BP 100 mg/5 ml and Paracetamol 200 mg/5ml.) on the anesthetic efficacy of buccal infiltration in vital pulpotomy of…
- Trial name
- NCT03423329
- Testing
- Brufen, Cital
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Posterior Spine Surgery
Kyphoscoliosis Surgery: Blood Conservation and Analgesia
Since the first spinal fusion by Hibbs 1911, yet anesthesia for correction of scoliosis is challenging due to frequently associated co-morbidities, the extensive nature of surgery and liability for many complications.
- Trial name
- NCT03319563
- Testing
- Local anesthetic-epinephrine, Saline
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Arthroplasty, Replacement, Knee
Intraarticular Analgesia After Total Knee Arthroplasty, a Randomised Study
The study aims to compare two different kinds of pain treatment after total knee replacement (operation with artificial knee joint): 1) a large local injection in and around the knee, supplemented with injection the day after, or…
- Trial name
- NCT00269529
- Testing
- femoral nerve block, knee infiltration and injection via catheter
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Anesthesia, Local
Local Anesthesia for Pediatric Cochlear Implant
Propofol with remifentanil provides good operative conditions for pediatric cochlear implant (CI); however, large doses of remifentanil usually result in postoperative hyperalgesia and increase postoperative pain.
- Trial name
- NCT03721081
- Testing
- Lidocaine 1%/Epi 1:200000, Na Cl 0.9%/Epi 1:200000
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Pain, Postoperative
Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study
The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound…
- Trial name
- NCT00508092
- Testing
- local anesthetic administration
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Royal Berkshire NHS Foundation Trust
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan