Clinical trials: Learning Disorders, Specific
Developmental Dyslexia, Reading Problem
Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties
Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization…
- Trial name
- NCT06947512
- Testing
- Seleggo Test
- Where
- 3 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Reading Disability, Anxiety
Evidence-Based Interventions to Enhance Outcomes Among Struggling Readers
Despite decades of research on reading disabilities, little is known about improving reading in the middle grades (i.e., grades 3-6) and advancements have been hindered by the narrow focus on reading problems alone without…
- Trial name
- NCT04059939
- Testing
- Reading, Anxiety Management, Classroom Business as Usual
- Where
- United States
- Volunteers
- 542 people
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
Learning Potential of Patients With Parkinson's Disease After Two Weeks of Targeted Touchscreen Training
Parkinson's disease (PD) is characterized by severe motor and non-motor symptoms, including upper limb dysfunction. Due to the degradation of dopaminergic neurons in the striatum, PD patients experience difficulties with motor…
- Trial name
- NCT05696197
- Testing
- Targeted touchscreen training
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- KU Leuven
Reading Disorder
Gene x Environment Interplay in Developmental Dyslexia Treatment: A Round-trip Translation Between Humans and Animal
Developmental dyslexia affects 7% of school-age children (Male:Female ratio of 1.5:1) and incurs disadvantages in education and occupation.
- Trial name
- Gedys (NCT06186882)
- Testing
- Action Video-Game
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Dyslexia
Validating a Neurocognitive Remediation Model for Visual-Attentional Pathway in Chinese Developmental Dyslexia
Developmental dyslexia is a common and serious specific learning disability affecting up to one in eight children in Hong Kong, with profound consequences for academic success and personal well-being.
- Trial name
- NCT07707700
- Testing
- Action video game intervention group, Active Control (Non-Action Video Game) Group
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The Hong Kong Polytechnic University
Developmental Dysgraphia
Sensory Motor Lateralization as Handwriting Intervention in School-Based OT
Children who attend School-Based Occupational Therapy (SBOT) show mixed dominance and a liable decreased in the structural and functional differentiation between the two hemispheres.
- Trial name
- SML (NCT03903614)
- Testing
- SML, CON
- Volunteers
- 16 people
- Sponsor
- Mary H. Teng
Colorectal Cancer Metastatic, Colorectal Cancer Stage III
COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer
This is an early phase I, single-arm, open-label clinical study designed to evaluate the safety, tolerability, and feasibility of COLONYVAQ-CRC, a physics-aware, quantum-classical AI-guided personalized neoantigen peptide…
- Conditions
- Colorectal Cancer Metastatic, Colorectal Cancer Stage III, Colorectal Cancer Stage IV
- Trial name
- COLONYVAQ™-CRC (NCT07328087)
- Testing
- Experimental: COLONYVAQ-CRC + mFOLFOX6 or CAPOX + Nivolumab
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- Biogenea Pharmaceuticals Ltd.
Central Auditory Processing Disorder, Dyslexia
Development of an Arabic Central Auditory Processing Remediation Program for Dyslexic Children With(C)APD
Rehabilitation of dyslexic children with (cental) auditory processing disorder. The first group will receive the proposed program the arabic version of differential processing training program and the control group will receive…
- Trial name
- NCT04708899
- Testing
- arabic version of differential processing training program, Arabic computer based auditory traing program(CBAT)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Rana ElShafaei
Dyslexia, Dysphasia
Developmental Language Difficulties: Behavioural and Electrophysiological Studies
This study will help to better characterize oral and written language disorders and determine if these disorders are continuous or not.
- Trial name
- LANGAGE (NCT02872870)
- Testing
- auditory lexical decision task, electroencephalogram
- Where
- 3 sites in Belgium, France
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Developmental Dyslexia, Developmental Coordination Disorder
Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD)
All the studies underlined the high frequency of co-morbid associations in specific learning disorders. Understanding the reasons for these associations could enable us to determine the cerebral bases that underlie each disorder.
- Trial name
- FMRI-DCD-DD (NCT02393729)
- Testing
- Neuropsychological assessment, MRI Study
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Acquisition of Literacy Skills for All Children, Including Those With SLDs, Appropriateness of Referrals for SLD Assessment for Accurate Early Detection of SLDs
Literacy Skills Improvement and Early Diagnosis of Specific Learning Disorders (SLD) Using a New Phono Syllabic Program
Scientific evidence shows that systematic phonological approaches are more effective than other methods in teaching children to read and should therefore be adopted in schools.
- Trial name
- ALFABETO (NCT07510126)
- Testing
- Alfabeto program, Other literacy teaching methods
- Where
- Italy
- Volunteers
- 1,407 people
- Sponsor
- IRCCS Burlo Garofolo
Attention Deficit Hyperactivity Disorder, Dyslexia
Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia
This study will evaluate the effects of atomoxetine on brain activation during attention and reading tasks via functional Magnetic Resonance Imaging (fMRI) in participants ages 10 to 16 years old with ADHD and comorbid dyslexia
- Trial name
- NCT00716274
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Eli Lilly and Company
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Developmental Dyslexia
Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia
Dyslexia is a common reading disorder. Specialized instructional programs can improve reading ability in children with dyslexia.
- Trial name
- NCT00068835
- Testing
- Lindamood-Bell training for dyslexia
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Learning Disorders, Dyslexia
Efficacy of a Two-Year Intensive Reading Intervention for Middle School English Learners With Reading Difficulties
This study investigates the efficacy of a reading comprehension intervention for English learners in Grades 6 and 7 with reading difficulties.
- Trial name
- TCLD (NCT03695068)
- Testing
- RISE Intervention
- Where
- 2 sites in United States
- Volunteers
- 840 people
- Sponsor
- University of Houston