Clinical trials: Large Language Model
HPV Vaccination Rates, HPV Vaccine Awareness
Effectiveness of Large Language Model-Based Chatbot Among Parents of Junior High School Girls in Improving Human Papillomavirus (HPV) Vaccine Awareness, Intention and Vaccination Rates
This is an interventional study targeting parents of junior high school girls. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates among parents' junior high…
- Conditions
- HPV Vaccination Rates, HPV Vaccine Awareness, HPV Vaccination Intention
- Trial name
- NCT07525245
- Testing
- Scientific videos, Vaccine chatbot
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Peritoneal Dialysis (PD), Large Language Models
A Simulated Case Study of a Peritoneal Dialysis-Specialized Large Language Model Assisting Doctors in Improving Decision-Making in Peritoneal Dialysis Management
This study is a randomized controlled trial based on simulated clinical cases, aiming to establish a standardized evaluation system for PD physicians, to assess the differences in PD management quality between a workflow assisted…
- Trial name
- NCT07724327
- Testing
- Peritoneal dialysis-specialized large language model.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Ophthalmology, Large Language Models
A Multimodal AI Agent for Ophthalmic Clinical Decision Support
This study is a multicenter randomized controlled trial evaluating the effectiveness and safety of EyeAgent, a multimodal artificial intelligence (AI) agent designed to assist ophthalmologists in clinical decision-making.
- Conditions
- Ophthalmology, Large Language Models, AI Agent, Eye Disease
- Trial name
- NCT07401459
- Testing
- EyeAgent AI system
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Ophthalmic Diseases (Specific Types Not Restricted)
Research on the Real-World Community Application of Large Language Models
There is an imbalance between the supply and demand of eye care services, especially in local communities and remote areas. To address this, it's important to use new intelligent technologies to expand the reach of eye disease…
- Trial name
- NCT06966882
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pediatric Advanced Life Support (PALS)
Comparing the Effectiveness of Large Language Model-Based and Video-Based Refresher Education on Knowledge Retention After Simulation-Based Pediatric Cardiopulmonary Resuscitation Training: A Six-Month Follow-Up Study
This study aims to compare the effectiveness of large language model (LLM)-based refresher education and video-based refresher education for maintaining knowledge and performance after simulation-based Pediatric Advanced Life…
- Trial name
- NCT07783932
- Testing
- LLM-Based Refresher Education, Video-Based Refresher Education
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Complete Blood Count Review
Multi-center Validation Study of a Large Language Model-based Intelligent Agent for Blood Cell Analysis
I. Study Background: Currently, in most medical institutions, the review of blood cell analysis still heavily relies on manual verification by laboratory staff.
- Trial name
- NCT07607184
- Testing
- LLM-Assisted Review Group
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Tobacco Use, Smoking Cessation
Chatbot Counselling for Smoking Cessation in Youths
The goal of this pilot trial is to develop and examine the trial feasibility and acceptability of a chatbot for smoking cessation in youth smokers. Specific aims include: 1.
- Trial name
- NCT06470776
- Testing
- Chatbot counselling, Peer counselling
- Where
- Hong Kong
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Education, Artificial Intelligence (AI)
AI Virtual Patient Training for Dental Student History Taking
This randomized study evaluated whether an artificial intelligence-assisted virtual patient could support third-year dental students in practicing medical and dental history taking.
- Conditions
- Dental Education, Artificial Intelligence (AI), Virtual Patient, History Taking
- Trial name
- NCT07688668
- Testing
- Gemini-Based AI Virtual-Patient Training, Conventional Role-Play Training
- Where
- Vietnam
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Healthy Adult
Effectiveness of AI-Assisted Antibiotic Prescribing
This randomized controlled trial aims to evaluate the impact of providing LLM access to physicians on antibiotic prescribing appropriateness, using a composite outcome instrument, the Antibiotic Prescribing Appropriateness Score…
- Trial name
- NCT07833293
- Testing
- ChatGPT
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Clinical Decision-making
Physician Reasoning on Management Cases With Large Language Models
This study will evaluate the effect of providing access to GPT-4, a large language model, compared to traditional management decision support tools on performance on case-based management reasoning tasks.
- Trial name
- NCT06208423
- Testing
- GPT-4
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Stanford University
Medical Student
AI-Assisted Learning in Medicine
This multi-center retrospective cohort study investigates the real-world impact of integrating MetaGP-Edu, a proprietary AI tool fine-tuned for medical education, into the undergraduate Internal Medicine curriculum.
- Trial name
- NCT06945159
- Where
- 2 sites in China
- Volunteers
- 1,632 people, healthy volunteers welcome
- Sponsor
- Kang Zhang
HCM - Hypertrophic Cardiomyopathy
Automated Reports Generation of Cardiovascular Magnetic Resonance Imaging
The goal of this observational study is to evaluate the accuracy, completeness, and clinical consistency of large language model-generated cardiac magnetic resonance (CMR) imaging reports compared with expert radiologist reports…
- Trial name
- NCT07340762
- Testing
- large lanuage model
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Medical Education, Artificial Intelligence in Medicine
An AI Educational Agent for Medical Machine Learning Courses
The goal of this interventional study is to evaluate the effectiveness of a Large Language Model (LLM)-based educational AI Agent in graduate students (Masters and PhD) specializing in medicine or nursing who are enrolled in the…
- Trial name
- NCT07449182
- Testing
- KGRAG-based AI Educational Agent System
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Diagnosis
Physician Reasoning on Diagnostic Cases With Large Language Models
This study will evaluate the effect of providing access to GPT-4, a large language model, compared to traditional diagnostic decision support tools on performance on case-based diagnostic reasoning tasks.
- Trial name
- NCT06157944
- Testing
- GPT-4
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
The Emergency Response Capabilities of Nurses (Including Occupational Protection, Critical Thinking, Communication Skills and Humanistic Care, Etc.)
Development and Evaluation of a Large Language Model - Based Training Program for Nurses in Public Health Emergencies
The goal of this randomized controlled trial is to evaluate the immediate efficacy of a Large Language Model (LLM)-assisted training program in enhancing nurses' emergency response capabilities in 204 practicing nurses with ≤5…
- Trial name
- NCT07141433
- Testing
- LLM-Assisted Public Health Emergency Training Program, Standard Public Health Emergency Training Program
- Where
- China
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Acute Respiratory Distress Syndrome, Pneumonia in Children
AI-Guided Mechanical Ventilation in Children: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to evaluate whether an AI-driven decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients), Congenital Heart Disease in Children
- Trial name
- NCT07728136
- Testing
- AI-generated recommendations for ventilator parameters.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wu Rongzhou
Pathologic Processes, Disease
Diagnostic Reasoning With Customized GPT-4 Model
This study will assess the impact of immediate access to a customized version of GPT-4, a large language model, on performance in case-based diagnostic reasoning tasks.
- Trial name
- NCT06911645
- Testing
- Immediate access to customized version of GPT-4, Access to customized version of GPT-4 following use of conventional resources
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Self-Directed Learning, Artificial Intelligence
ChatGPT Helping Advance Training for Medical Students: A Study on Self-Directed Learning Enhancement
The goal of this clinical trial is to evaluate the effect of LearnGuide, a custom GPT developed with ChatGPT for supporting self-directed learning (SDL) in medical students.
- Conditions
- Self-Directed Learning, Artificial Intelligence, Medical Education
- Trial name
- CHAT-MS (NCT06276049)
- Testing
- custom GPT supported self-directed learning
- Where
- China
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Wang Shalong
Myopia, Large Language Model
Development and Validation of a Large Language Model-based Myopia Assistant System
Myopia is a rapidly growing global health concern, and there is an urgent need for advanced tools that can facilitate personalized healthcare strategies.
- Trial name
- NCT06607822
- Testing
- A patient-centered assistant system based on Large-Language Model (LLM)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Non-emergency Ocular Diseases
Evaluate the Performance of Large Language Models in Ophthalmologic Patient Consultation
The intelligent image models lack an understanding of diagnostic and treatment logic, and have not considered textual information such as symptoms and signs.
- Trial name
- NCT06824389
- Testing
- Consultation Model of large language model in Ophthalmology Clinics
- Where
- China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University