Clinical trials: Knee Replacement
Knee Osteoarthritis
Is Isokinetic Testing an Indicator of Total Knee Arthroplasty
In this study, investigators analyzed whether the isokinetic knee muscle strength of patients undergoing unilateral total knee arthroplasty (TKA) is a predictor for surgery.
- Trial name
- NCT05668546
- Testing
- isokinetic testing CSMI HUMAC NORM instrument
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Bahçeşehir University
Arthroplasty, Replacement, Knee
Early Clinical Results of Mobile-Bearing Revision Total Knee Arthroplasty
Long term follow-up is needed to determine whether current Mobile Bearing revision Total Knee Arthroplasty (TKA) designs will improve implant longevity.
- Trial name
- MBT (NCT01398800)
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Colorado Joint Replacement
Osteoarthritis Knee
Comparison of an Old Versus a New Total Knee Replacement
A randomized controlled clinical and RSA study, comparing 2 knee implants: 1. NexGen CR cemented total knee arthroplasty 2. Persona CR cemented total knee arthroplasty 3 hospitals will participate in the study: Helse Bergen HF…
- Trial name
- NCT03548792
- Testing
- RSA radiostereometric analysis, Clinical comparison
- Where
- Norway
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Helse-Bergen HF
Hyperglycemia
Postoperative Hyperglycemia After Knee Primary Knee Arthroplasty Surgery
Patients in three hospitals in Sweden who will have knee arthroplasty surgery for the first time are invited to participate in the study, approximately 2000 patients.
- Trial name
- NCT03830931
- Where
- Sweden
- Volunteers
- 1,448 people
- Sponsor
- Lund University
Knee Arthroplasty
Multimodal Modeling of the Knee Joint
The trial will contribute to the development of an innovative algorithm that aims to simplify and improve preoperative knee surgical decision.
- Trial name
- KneeMod (NCT04179812)
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Knee Osteoarthritis
The Influence of Coronally Knee Alignment on the Tibial Tuberosity Rotation
The primary aim of this study is to find a possible correlation between tibial tuberosity rotation and coronal leg alignment. If correlation exists, a more individual tibial component rotation might be proposed during a total…
- Trial name
- NCT05295602
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- Valdoltra Orthopedic Hospital
Osteo Arthritis Knee
Post-op Ketamine Study
The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption.
- Trial name
- NCT03865550
- Testing
- Isotonic saline, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rothman Institute Orthopaedics
Cryotherapy Effect
Cryocompression After Total Knee Arthroplasty
The overall aim of this study is to evaluate the effectiveness of a cryocompression device after total knee arthroplasty (TKA) compared to standard therapy.
- Trial name
- NCT05395273
- Testing
- Game Ready cryocompression
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Complete Contact, Incomplete Contact
Comparison of Post-operative Knee Range of Motion and Functions Between Intraoperative Complete and Incomplete Patellofemoral Articular Contacts in Patients Undergoing Total Knee Arthroplasty
The purpose of this study is to compare clinical outcome in knee range of motion and functions between intraoperative complete and incomplete patellofemoral articular contacts
- Trial name
- NCT05349461
- Testing
- Complete patellofemoral articular contact, Incomplete patellofemoral articular contact
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Navamindradhiraj University
Knee Instability in Total Knee Artrhroplasty
Knee Arthroplasty Instability Study
Total knee replacement (TKR) instability is a poorly defined entity. The diagnosis is based on symptoms and clinical tests of knee laxity.
- Trial name
- KISS (NCT05676437)
- Testing
- Stress radiography
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diakonhjemmet Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
Central Sensitization and Alteration of Circulating Neurosteroid
For patients who underwent two-stage replacement of both knee joints (one knee surgery - one week term- the other knee surgery), postoperative pain and analgesic usage with patient-controlled analgesia (PCA) increased at the…
- Trial name
- NCT03298711
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Bundang Hospital
Complications; Arthroplasty
A Comparison Between an Individual Low Tourniquet Pressure Versus a Standard Pressure During Total Knee Arthroplasty
The use of bloodless field is a helpful and important method in orthopedic surgery. The surgery can be done without interrupting bleedings, while keeping an exact overlook of the anatomy.
- Trial name
- NCT01442298
- Testing
- Limb occlusion pressure (LOP), conventional measurement method
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Charlotta Olivecrona
Arthroplasty, Replacement, Knee, Synovectomy
Synovectomy in Primary Total Knee Arthrplasty
The aim of total knee arthroplasty is to achieve best patient functional outcomes, improve patient pain score and satisfaction. Synovial proliferation is a common finding in arthritic knees.
- Trial name
- NCT03778463
- Testing
- Synovectomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Surgery, Cataract
Routine Surgical Procedures During COVID-19 Pandemic: a French Nationwide Cohort Study
Determine the consequences of COVID-19 pandemic on routine targeted surgeries. Five surgical procedures were considered : cataract surgery, hip and knee arthoplasties, coronary revascularisation by angioplasty and definitive…
- Conditions
- Surgery, Cataract, Hip Arthroplasty, Knee Arthroplasty
- Trial name
- NCT05197660
- Testing
- surgical procedures
- Where
- France
- Volunteers
- 2,000,000 people
- Sponsor
- EPI-PHARE
Osteoarthritis, Rheumatoid Arthritis
PS150 Total Knee Arthroplasty Outcomes Registry
This registry is intended to evaluate the clinical outcomes of the DePuy P.F.C. Sigma PS150 RP Total Knee System. 200 participants will be enrolled prospectively or retrospectively and the follow up period will be 5 years.
- Trial name
- NCT02319291
- Testing
- P.F.C. Sigma PS150 RP Total Knee System
- Where
- 4 sites in Australia, South Korea
- Volunteers
- 175 people
- Sponsor
- DePuy Orthopaedics
Total Knee Replacement
The Clinical Observation on Taping After Total Knee Replacement
The investigators will conduct a single-blind, randomized controlled trial of 100 patients with total knee replacement. Patients will be randomly assigned into a control group and an intervention group.Both groups received same…
- Trial name
- taping (NCT03340584)
- Testing
- the Nine Castle Net Format Taping, traditional rehabilitation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Osteo Arthritis Knee, Arthroplasty, Replacement, Knee
Sharp Dissection Versus Monopolar Electrocautery in Primary Total Knee Arthroplasty Performed Under Tourniquet
This study compares the use of sharp dissection with diathermy for the approach to a total knee replacement. Half of the patients will be randomly assigned each intervention.
- Trial name
- NCT03559478
- Testing
- Sharp dissection with scalpel plus electrocautery to vessels, Electrocautery for all dissection
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Infirmary of Edinburgh
Total Knee Arthroplasty, Body Mass Index
Short-Term Follow-up Indicator for Total Knee Arthroplasty and Body Mass Index
The main purpose of this study is to determine the influence of obesity on the short term follow-up indicators of a polyvalent geriatric rehabilitation clinic after total knee arthroplasty.
- Conditions
- Total Knee Arthroplasty, Body Mass Index, Rehabilitation
- Trial name
- NCT02983929
- Testing
- Rehabilitation after total knee arthroplasty
- Volunteers
- 244 people
- Sponsor
- Centre Hospitalier Durécu Lavoisier
Knee Arthroplasty
The Energize! Study for Adults With Knee Replacement
The purpose is to examine the effects of an online physical activity program on moderate to vigorous intensity physical activity, pain, and physical function in adults with knee replacement at 3 months (post-intervention) and 6…
- Trial name
- NCT06096727
- Testing
- Energize!
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Preoperative Period, Nutritional Status
Preoperative Nutritional Status in Patients Undergoing Elective Total Knee Arthroplasty and In-hospital Postoperative Complications
Malnutrition has long been linked to postoperative complications and adverse outcomes in a variety of surgical fields , such as increased susceptibility to infection, delayed wound healing, and increased frequency of decubitus…
- Conditions
- Preoperative Period, Nutritional Status, Arthroplasty Knee
- Trial name
- NUTR TKA (NCT03549962)
- Testing
- TKA
- Where
- 2 sites in Hong Kong
- Volunteers
- 626 people
- Sponsor
- Chinese University of Hong Kong