Clinical trials: Knee
Knee Osteoarthritis
Effectiveness of Using a Chatbot to Promote Adherence to Home Physiotherapy
A Chatbot oriented to virtually assist patients in a physiotherapy treatment has been designed and developed to interact with patients with musculoskeletal disorders in need for domiciliary rehabilitation.
- Trial name
- NCT05363137
- Testing
- Chatbot Assistant, Standard care
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- University of Valencia
Phantom Limb Pain
Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Limb amputation results in many types of pain, including localized pain at the stump and projected pain experienced by the patient in the location where the amputated limb used to be, known as phantom limb pain (PLP).
- Trial name
- NCT06428123
- Testing
- Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Superior University
Knee Osteoarthritis
Is Isokinetic Testing an Indicator of Total Knee Arthroplasty
In this study, investigators analyzed whether the isokinetic knee muscle strength of patients undergoing unilateral total knee arthroplasty (TKA) is a predictor for surgery.
- Trial name
- NCT05668546
- Testing
- isokinetic testing CSMI HUMAC NORM instrument
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Bahçeşehir University
Anterior Cruciate Ligament Injuries
Clinical Application of the Apex of the Deep Cartilage in Evaluating the Femoral Tunnel of the ACL Reconstruction
With the apex of the deep cartilage (ADC) as the symbol, the consistency of the two methods in the postoperatively computed tomography (CT) and microscopic evaluation of the position of the femoral tract of the anterior cruciate…
- Trial name
- NCT04953546
- Testing
- No Intervention
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking University Third Hospital
Osteoarthritis
Lateral Wedge Insole With Subtalar Strapping for Knee Osteoarthritis
This is a clinical study to evaluate the efficacy of a lateral wedge insole with subtalar strapping in knee osteoarthritis treatment.
- Trial name
- NCT01739296
- Testing
- Lateral wedge insole with subtalar strapping
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Osteochondral Defect
Evaluating Cryopreserved Osteochondral Allograft Cores for the Treatment of Osteochondral Lesions in the Knee
The primary objective of this study is to obtain evidence of the effectiveness of Cryopreserved Osteochondral Allograft Core in the treatment of osteochondral lesions on the femoral condyle.
- Trial name
- NCT06216756
- Testing
- osteochondral transplant on the femoral condyle
- Where
- 6 sites in United States
- Volunteers
- 68 people
- Sponsor
- AlloSource
Anterior Cruciate Ligament Tear
IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Injury to the knee during sports participation often involves partial or full detachment of the anterior cruciate ligament (abbreviated as ACL). ACL tears cause pain, swelling and inflammation.
- Trial name
- EASI ACL (NCT02930122)
- Testing
- anakinra (150mg), Saline intraarticularly
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cale Jacobs, PhD
Femoro Acetabular Impingement
Analysis of Radiographic and Kinematic Features in FAI Patients
The goal of this observational study is to describe the radiographic and kinematic features in patients with femoroacetabular impingement syndrome (FAI).
- Trial name
- NCT05867069
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction
To evaluate the effect of graded exposure and mindfulness meditation after ACLR, the investigators will determine the effect of graded exposure and mindfulness meditation to 1) decrease self-reported injury-related fear and…
- Trial name
- NCT05949177
- Testing
- Graded Exposure and Mindfulness Meditation, Waitlist Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Arthroplasty, Replacement, Knee
Early Clinical Results of Mobile-Bearing Revision Total Knee Arthroplasty
Long term follow-up is needed to determine whether current Mobile Bearing revision Total Knee Arthroplasty (TKA) designs will improve implant longevity.
- Trial name
- MBT (NCT01398800)
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Colorado Joint Replacement
Osteoarthritis Knee
Comparison of an Old Versus a New Total Knee Replacement
A randomized controlled clinical and RSA study, comparing 2 knee implants: 1. NexGen CR cemented total knee arthroplasty 2. Persona CR cemented total knee arthroplasty 3 hospitals will participate in the study: Helse Bergen HF…
- Trial name
- NCT03548792
- Testing
- RSA radiostereometric analysis, Clinical comparison
- Where
- Norway
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Helse-Bergen HF
Hyperglycemia
Postoperative Hyperglycemia After Knee Primary Knee Arthroplasty Surgery
Patients in three hospitals in Sweden who will have knee arthroplasty surgery for the first time are invited to participate in the study, approximately 2000 patients.
- Trial name
- NCT03830931
- Where
- Sweden
- Volunteers
- 1,448 people
- Sponsor
- Lund University
Knee Arthroplasty
Multimodal Modeling of the Knee Joint
The trial will contribute to the development of an innovative algorithm that aims to simplify and improve preoperative knee surgical decision.
- Trial name
- KneeMod (NCT04179812)
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Osteo Arthritis Knee and Hip, Artificial Intelligence (AI)
Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients
This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with…
- Conditions
- Osteo Arthritis Knee and Hip, Artificial Intelligence (AI), Acceptability, Accuracy
- Trial name
- PARTICIPATE (NCT07202286)
- Where
- Netherlands
- Volunteers
- 286 people
- Sponsor
- Canisius-Wilhelmina Hospital
Chronic Knee Instability
Interest of Additional Arthroscopic Portals in Diagnosis of Hidden Lesions of the Medial Meniscus in Pediatrics Knees With ACL Deficiency
Peroperatively observative study in pediatric orthopedic center in Lyon, France. 50 pediatric patients included in this study, to improve the diagnosis of hidden lesions of the medial meniscus associated with lesions of the…
- Trial name
- NCT02425995
- Testing
- Arthroscopic intercondylar and posteromedial portal
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Knee Osteoarthritis
The Influence of Coronally Knee Alignment on the Tibial Tuberosity Rotation
The primary aim of this study is to find a possible correlation between tibial tuberosity rotation and coronal leg alignment. If correlation exists, a more individual tibial component rotation might be proposed during a total…
- Trial name
- NCT05295602
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- Valdoltra Orthopedic Hospital
Dislocated Patella, Torn Medial Patellofemoral Ligament
Repair of Medial Patellofemoral Ligament Compared to Conservative Treatment for First Time Patella Dislocation
Background: The forces involved in a patella dislocation event can cause significant collateral damage involving the articular cartilage of the patella femoral joint.
- Trial name
- NCT02185001
- Testing
- Direct Medial Patellofemoral Ligament (MPFL) Repair, Physical therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Orthopedic Specialty Institute
Anterior Cruciate Ligament Injuries
Steps Towards Osteoarthritis Prevention
Optimal knee joint loading, which refers to the forces acting on the knee caused by daily activities such as daily steps, plays an essential role in maintaining knee articular cartilage health and reducing the risk of…
- Trial name
- STOP (NCT06193343)
- Testing
- Adaptive Daily Step Promotion
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Georgia
Osteo Arthritis Knee
Post-op Ketamine Study
The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption.
- Trial name
- NCT03865550
- Testing
- Isotonic saline, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rothman Institute Orthopaedics
Rupture of Anterior Cruciate Ligament
The Effect of Early WBVT on Neuromuscular Control After ACLR
To investigate the effect of early WBVT on neuromuscular control after ACLR.
- Trial name
- WBVT (NCT01300182)
- Testing
- Whole body vibration therapy, Control
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- Chinese University of Hong Kong