Clinical trials: Kidney Failure, Acute
Chronic Kidney Disease, Chronic Renal Failure
Karolinska Cardiorenal Theme-centre and StockholmHeartbank
Chronic kidney disease (CKD) affects 10-18% of the adult population and is becoming recognized as one of the most serious disorders causing increased risk for cardiovascular disease and death.
- Conditions
- Chronic Kidney Disease, Chronic Renal Failure, Acute Coronary Syndrome, Ischemic Heart Disease
- Trial name
- KKT (NCT01204645)
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Danderyd Hospital
Alzheimer Disease, Late Onset, Stroke
Explore the Sharing Model Intervene to Improve the Knowledge, Attitudes, Service Intentions and Service Start-up Effects of the Eight Major Non-cancer Disease End-stage Caregivers on Well-being and Palliative Care
Since September 1st, 2009, Taiwan has begun to pay attention to the care of patients with organ failure, dementia and the elderly, and brought eight of non-cancer terminal patients into health insurance subsidies to implement the…
- Conditions
- Alzheimer Disease, Late Onset, Stroke, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT05407272
- Testing
- Health Education Manual, manual
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wen-Shiou Pan
Malaria, Sepsis
Optimal Fluid Management in Adult Severe Malaria
Optimal fluid therapy in severe falciparum malaria has not been well defined, especially in resource poor settings where access to mechanical ventilation is limited.
- Trial name
- DRIPICCO (NCT01936766)
- Where
- Bangladesh
- Volunteers
- 156 people
- Sponsor
- University of Oxford
In Acute Kidney Injury
The Relationship Between Serum and Urinary Angiotensinogen Levels and Long-Term Renal Prognosis in Acute Renal Injury
This study aims to retrospectively examine long-term (at the end of the 3rd year) renal function in the thesis study titled "Investigation of serum and urine angiotensinogen levels as a prognostic indicator of renal function in…
- Trial name
- Renal Injury (NCT07512661)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Critically Ill, Acute Kidney Injury
Magnesium Balance of Citrate-based Continuous Venovenous Hemofiltration, Effect of Citrate Dose.
Rationale: A higher citrate dose during continuous venovenous hemofiltration provides better anticoagulation but possibly a higher risk of citrate accumulation in case of metabolic limitations.
- Trial name
- NCT02194569
- Testing
- Citrate
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Ziekenhuis Oost-Limburg
Acute Kidney Injury
Peritoneal Dialysis vs Furosemide for Acute Kidney Injury After Cardiopulmonary Bypass
Acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in infants is common and associated with poor outcomes. Peritoneal dialysis (PD) and furosemide have been used to attain negative fluid balance due to AKI induced…
- Trial name
- NCT01709227
- Testing
- Furosemide, Peritoneal Dialysis
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stem Cell Transplant Complications, Acute Graft Versus Host Disease
Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study
This study aims to establish a cohort of 500 patients with hematological disease who undergoing allogeneic hematopoietic stem cell transplantation in the northwest region.
- Conditions
- Stem Cell Transplant Complications, Acute Graft Versus Host Disease, Acute Kidney Injury, Major Adverse Cardiac Events
- Trial name
- NCT06386445
- Testing
- Serum metabolomics sequencing
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Kidney Injury, Drug Use
A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP)
This observational retrospective study aims to learn about the incidence of acute kidney (AKI) injury in newborns in infants exposed to nephrotoxic drugs with a big data approach.
- Conditions
- Acute Kidney Injury, Drug Use, Drug Interaction, Drug Toxicity
- Trial name
- NeoAKISTOP (NCT05851222)
- Where
- Italy
- Volunteers
- 4,200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Covid19, Kidney Transplant Infection
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Methods: Out of 2000 kidney transplant recipients in our center in Kuwait, collecting data was started for all COVID-19-positive kidney transplant recipients till August 2020.
- Conditions
- Covid19, Kidney Transplant Infection, Risk Factor, Cardiovascular, Immunosuppression
- Trial name
- OMC-KTR (NCT04542954)
- Testing
- Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
- Where
- Kuwait
- Volunteers
- 104 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Cardiovascular Disease, Renal Insufficiency, Acute
Acetylcysteine Against Acute Renal Insult During Cardiopulmonary Bypass.
The purpose of this study is to determine whether N-acetylcysteine is effective in the prophylaxis of post-cardiopulmonary bypass acute renal impairment.
- Conditions
- Cardiovascular Disease, Renal Insufficiency, Acute, Cardiopulmonary Bypass
- Trial name
- NCT00190034
- Testing
- N-Acetylcysteine 600mg/tab
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Congenital Heart Disease, Surgery--Complications
A Predictive Score System for AKI Following Pediatric Cardiac Surgery
Acute kidney injury (AKI) has been recognized as a typical post- operative complication among the children undergoing surgical repair of a congenital cardiac defect.
- Conditions
- Congenital Heart Disease, Surgery--Complications, Acute Kidney Injury
- Trial name
- NCT05489263
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Scoliosis, Acute Kidney Injury
Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair
Surgery for scoliosis correction, the abnormal curvature of the spine, is a major procedure often undertaken in adolescents. In adult anesthesia, there is a large volume of literature debating how to optimize fluids administered…
- Trial name
- CardioQ-RP (NCT02463175)
- Testing
- Plasmalyte, Goal-directed fluid therapy (GDT)
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Acute Kidney Injury
Acute Kidney Injury in Pediatric Polytrauma Patients at Assiut University Trauma Unit: A Cross-Sectional Study on Incidence and Predictive Risk Factors
This study aims to investigate the true incidence and clinical presentation of post-traumatic AKI in hospitalized pediatric patients and identify the risk, and severity of AKI.
- Trial name
- NCT06177886
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Kidney Injury, Chronic Kidney Disease
Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis
Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Hypertension
- Trial name
- IMPRESS (NCT02372721)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Renal Insufficiency, Acute Kidney Injury
Efficacy of Point-Of-Care Creatinine Assays in Patients With eGFR <30 Receiving Intravascular Contrast
Point-of-care (POC) creatinine devices allow rapid measurement of creatinine levels and calculation of estimated glomerular filtration rate (eGFR) which give an indication of renal function.
- Conditions
- Renal Insufficiency, Acute Kidney Injury, Contrast-induced Nephropathy
- Trial name
- EPIC (NCT04597892)
- Testing
- serum creatinine assay
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center
Acute Kidney Injury
A Multi-Center Study of a SCD for Immunomodulatory Dysregulation in Pediatric AKI
The SCD PED-02 trial is examining the safety and efficacy of the Selective Cytopheretic Device (SCD) in treating pediatric acute kidney injury (AKI).
- Trial name
- SCD PED-02 (NCT04869787)
- Testing
- Selective Cytopheretic Device
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Kidney Injury
Prospective Validation of AKI Prediction
The purpose of this prospective observational study is to implement, deploy, and quantify accuracy of an existing Pediatric Early AKI Risk Score algorithm.
- Trial name
- NCT06804200
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Adam C Dziorny
Sickle Cell Disease, Kidney Injury
Acute Kidney Injury in Patients With Sickle Cell Disease
Patients with sickle cell disease may be at risk for acute kidney injury (AKI)during sickle cell crisis (pain or acute chest syndrome).
- Conditions
- Sickle Cell Disease, Kidney Injury, Kidney Diseases, Kidney Disease, Chronic
- Trial name
- NCT03105271
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Acute Kidney Injury
Incidince of Acute Kidney Injury in Children With Community Acquired Pneumonia at Assiut University Children Hospital
Descriptive prospective observational study of Incidince of acute kidney injury in children with community acquired pneumonia at assiut university children hospital
- Trial name
- NCT06117826
- Volunteers
- 100 people
- Sponsor
- Assiut University
Depression, Acute Kidney Injury
Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury
The purpose of this study is to determine if there is an excess risk of acute kidney injury (AKI) with Serotonin-norepinephrine reuptake inhibitors (SNRIs) as compared to Selective serotonin reuptake inhibitors (SSRIs), two…
- Trial name
- SNRI-AKI (NCT02320240)
- Testing
- Duloxetine, Venlafaxine, Desvenlafaxine
- Where
- Canada
- Volunteers
- 3,255,526 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES