Clinical trials: Irreversible Pulpitis
Irreversible Pulpitis
Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis
To compare the effect of different VPT methods using Calcium Enriched Mixture (CEM) cement for management of human dental pulp with irreversible pulpitis.
- Trial name
- NCT01561183
- Testing
- Indirect pulp capping (IPC), Direct pulp capping (DPC), Miniature pulpotomy (MP)
- Where
- Iran
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Pulpitis - Irreversible
Effect of Cryotherapy on Postoperative Pain in Vital Pulp Treatment of Molar Teeth
The goal of this clinical trial was to evaluate the effect of cryotherapy with salin solution on the intensity of postoperative pain after total pulpotomy procedures in molar teeth with symptomatic irreversible pulpitis.
- Trial name
- NCT06644703
- Testing
- Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Cukurova University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Carious Exposure of Pulp, Irreversible Pulpitis
Comparative Study of the Outcome of Partial and Full Pulpotomy in Irreversible Pulpits
This study aims at comparing the outcome of partial pulpotomy and full pulpotomy in the management of carious pulp exposures in permanent teeth with a clinical diagnosis of irreversible pulpits.
- Conditions
- Carious Exposure of Pulp, Irreversible Pulpitis, Pulpotomy
- Trial name
- NCT05279820
- Testing
- Partial pulpotomy, Full Pulpotomy
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Irreversible Pulpitis
Clinical and Radiographic Evaluation of Calcium Hypochlorite Versus Saline As Root Canal Irrigants in Pulpectomy of Primary Molars: a Randomized Clinical Trial
The aim of this study is to evaluate the clinical and radiographic success of Calcium Hypochlorite versus Saline as root canal irrigants in pulpectomy of primary molars.
- Trial name
- NCT06748781
- Testing
- Pulpectomy using 2.5% Calcium Hypochlorite root canal irrigant., Pulpectomy using Saline as root canal irrigant
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Irreversible Pulpitis
CGF Partial Pulpotomy Versus Endodontic Treatment
partial pulpotomy of mature molars with irrevesible pulptits using CGF in adolescents
- Trial name
- CGF Vs Endo (NCT07417098)
- Testing
- Other treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Irreversible Pulpitis
Evaluation of Bacterial Reduction After Pulpectomy in Primary Molars
The primary aim of the study is to compare the bacterial reduction in pulpectomy of primary molars using a single rotary file system versus conventional manual instrumentation.
- Trial name
- NCT07472751
- Testing
- Rotary Instrumentation, Manual Instrumentation
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Pulpitis - Irreversible
Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Inflammed Pulp
Group I (Experimental group I): Lesion Sterilization and Tissue Repair with radicular instrumentation. Coronal and accessible radicular pulp tissue are extirpated using rotary files.
- Trial name
- NCT05336682
- Testing
- Lesion Sterilization and Tissue Repair with radicular instrumentation, Lesion Sterilization and Tissue Repair without radicular instrumentation, Conventional pulpectomy
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Clinical and Radiographic Assessment of Bio C Repair, Biodentine and Mineral Trioxide Aggregate
The aim of this study is to assess Clinical and Radiographical effect of Bio C repair, Biodentine and Mineral Trioxide Aggregate when used as pulpotomy Agents in Immature Permanent Molars with Pulpits.
- Trial name
- NCT07522723
- Testing
- Biodentine, Bio C repair
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis (toothache)
Garlic Oil As Root Filling Material in Primary Molars
The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years.
- Trial name
- NCT06755502
- Testing
- Garlic oil, Calcium Hydroxide, Iodoform, paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment
Pulpotomy has been proposed in the last decade as a definitive treatment of mature permanent teeth with irreversible pulpitis due to the better understanding of the pulp biology and development of bioactive materials .
- Trial name
- NCT03916900
- Testing
- Pulpotomy, Root canal treatment
- Volunteers
- 52 people
- Sponsor
- Cairo University
Irreversible Pulpitis
Effect of Temperature Elevation on the Antimicrobial Efficacy of Two Root Canal Irrigants in Primary Root Canal Infections: A Randomized Controlled Clinical Trial
evaluate the antimicrobial efficacy of preheated sodium hypochlorite and dexamethasone sodium phosphate and at room temperature in patients with primary root canal infection.
- Trial name
- NCT07906925
- Testing
- Dexamethasone Sodium Phosphate 10 MG/ML, Sodium Hypochlorite 2,5%
- Volunteers
- 40 people
- Sponsor
- Tanta University
Cryotherapy Effect, Irreversible Pulpitis
Cryotherapy Efficacy During Pulp Therapy of the Mandibular First Permanent Molars in Children
The aim of the study is to assess the efficacy of cryotherapy application on the success of inferior alveolar nerve block (IANB) in reducing pain during pulp therapy of the mandibular first permanent molars with irreversible…
- Conditions
- Cryotherapy Effect, Irreversible Pulpitis, Pain
- Trial name
- NCT05441995
- Testing
- Cryotherapy
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis (toothache)
Comparison of Effectiveness of Hand Versus Rotary Instrumentation in Pulpectomy of Primary Second Molar Teeth.
To provide an effective technique for pulpectomy in primary second molar teeth in pakistani population, local studies are required.
- Trial name
- NCT06714305
- Testing
- Group B will be assigned to rotary instrumentation., will be assigned to rotary instrumentation.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- RANA AHMAD
Irreversible Pulpitis (Toothache), Dental Caries (Diagnosis)
Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis
The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first…
- Trial name
- NCT07046533
- Testing
- (pulpotomy), root canal treatment
- Volunteers
- 60 people
- Sponsor
- Lamiaa Saeed Ahmed Elshiekh
Post Operative Endodontic Pain
Reduction of Post-operative Endodontic Pain
To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.
- Trial name
- NCT01480752
- Testing
- Lornoxicam, normal saline, no injection
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Pulpitis - Irreversible
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically.
- Trial name
- NCT05582317
- Testing
- Biodentine, Simvastatin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Reversible Pulpitis, Irreversible Pulpitis
Biomarkers for Differentiating Reversible and Irreversible Pulpitis
This observational study aims to evaluate the role of inflammatory, oxidative stress, neurogenic, and immunological biomarkers obtained from pulpal blood in the differential diagnosis of normal pulp, reversible pulpitis, and…
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Healthy Pulp
- Trial name
- PULPBIOM (NCT07658742)
- Testing
- Pulpal Blood Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Safa
Pulpectomy, Pulpitis - Irreversible
Clinical and Radiographic Evaluation of E-IodoCal in Primary Molar Pulpectomy
This randomized controlled split-mouth clinical trial evaluates the clinical and radiographic performance of E-IodoCal paste compared to zinc oxide-eugenol (ZOE) as root canal filling materials in primary molar pulpectomies.
- Conditions
- Pulpectomy, Pulpitis - Irreversible, Zinc Oxide, Root Canal Obturation
- Trial name
- NCT07883200
- Testing
- E-IodoCal Root Canal Obturation (Group I), Zinc Oxide-Eugenol Root Canal Obturation (Group II)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University