Clinical trials: Intussusception
Intussusception
Minimally Invasive Surgical Management for Pediatric Intussusception: A Retrospective Cohort Study
Intussusception is the primary cause of intestinal obstruction in children aged 3 months to 5 years, leading to significant morbidity and mortality rates.
- Trial name
- NCT06351163
- Testing
- Laparoscopic reduction, Transumbilical mini-open reduction
- Where
- 2 sites in Vietnam
- Volunteers
- 181 people
- Sponsor
- National Children's Hospital, Vietnam
Intussusception, Rotavirus Infections
Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study
This is a prospective randomized clinical trial that aims to evaluate the potential effects of the first dose of rotavirus vaccines on gastrointestinal motility and anatomy and blood and stool cytokine responses.
- Trial name
- NCT02542462
- Testing
- Rotarix®,, Rotarix®, with other routine vaccines, RotaTeq®,
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Basilar Invagination
A Prospective Study of Natural History and Clinical Outcomes for Basilar Invagination
A Prospective Study of Natural History and Clinical Outcomes for Basilar Invagination
- Trial name
- NCT05909540
- Testing
- Posterior facet distraction and fusion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Pancreatic Anastomotic Leak
Comparative Study Between Duct to Mucosa and Invagination Pancreaticojejunostomy After Pancreaticoduodenectomy:
Postoperative pancreatic fistula (POPF) remains a challenge even at specialized centers, and also affect significantly the surgical outcomes .
- Trial name
- PJ (NCT02142517)
- Testing
- Duct to mucosa PJ group, Invagination PJ group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Intussusception
Pneumatic Reduction For Intussusception In Children: A Retrospective Cohort Study
In pediatric patients, intussusception predominantly occurs in the ileocecal region, with over 90% of cases lacking identifiable causative factors, initiating through peristalsis-driven invagination of bowel segments leading to…
- Trial name
- NCT06365333
- Testing
- Fluoroscopic-guided air-enema reduction (FGAR)
- Where
- 2 sites in Vietnam
- Volunteers
- 3,562 people
- Sponsor
- National Children's Hospital, Vietnam
Intussusception, LRTI-related Post Neonatal Deaths
Implementing Hospital-based Active Surveillance Procedures for Vaccine Safety Monitoring at IMSS Hospitals in Mexico
This is an epidemiology study designed to implement hospital-based active surveillance for intussusception (IS) in children <1 year of age and lower respiratory tract infection (LRTI)-related deaths among children between 29 days…
- Trial name
- NCT00436358
- Testing
- Not applicable: none
- Where
- Mexico
- Volunteers
- 134 people
- Sponsor
- GlaxoSmithKline
Intussusception (IS), Rotavirus Vaccines
Intussusception Surveillance After Rotarix Introduction in Mexico
GSK Biologicals' rotavirus vaccine, Rotarix™ has been recommended for universal use targeting infants through the Expanded Program on Immunization (EPI) in Mexico.
- Trial name
- NCT00595205
- Testing
- Hospital log review.
- Where
- Mexico
- Volunteers
- 786 people
- Sponsor
- GlaxoSmithKline
Intussusception
Effect of Hydrocortisone on Improving Outcome of Pneumatic Reduction of Infantile Intussusception
Intussusception is one of the most frequent causes of acute bowel and second most common cause of acute abdominal pain in pediatric age .95 % of cases are idiopathic, the rest are either due to pathological lead point or post…
- Trial name
- NCT02691858
- Testing
- Hydrocortisone, Saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Infections, Rotavirus
Special Drug Use Investigation for ROTARIX®
This study aims to determine the incidence of intussusceptions (IS) (including suspected cases of intussusception) after vaccination with Oral Rotarix® under clinical practice, in Japan.
- Trial name
- NCT01636739
- Testing
- Oral Rotarix®, Data collection
- Volunteers
- 10,982 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Intussusception
Study on the Incidence of Intussusception (IS) in Children Aged < 12 Months in Japan
This study aims to analyse baseline data on IS in order to monitor the possibility of increased risk of IS in children aged <12 months after introduction of the Rotarix vaccination in Japan.
- Trial name
- NCT01479491
- Testing
- Data collection
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Intestinal Atresia, Necrotizing Enterocolitis
The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
Background: Intestinal resections are commonly performed in the pediatric population. Perfusion of the bowel is one of the most important factors determining the viability of an intestinal anastomosis.
- Conditions
- Intestinal Atresia, Necrotizing Enterocolitis, Hirschsprung Disease, Gastroschisis
- Trial name
- NCT04020939
- Testing
- SPY imaging, Indocyanine Green
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Osteogenesis Imperfecta
Evaluation and Intervention for the Effects of Osteogenesis Imperfecta
We propose a longitudinal study of the natural history of types III and IV osteogenesis imperfecta for children age birth to 25 years.
- Trial name
- NCT00001594
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Intussusception
Seasonal Variations and Different Treatment Protocols of Intussusception in Children: Our Centers Experiences
Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood intussusception.
- Trial name
- NCT04454320
- Testing
- INTUSSUSCEPTION IN CHILDREN
- Volunteers
- 470 people
- Sponsor
- Minia University
Intussusception
Follow-up and Steroid Treatment Results in Intussusception
Treatment interventions in the treatment of intussusception are hydrostatic or pneumatic reduction and manual reduction with laparotomy.
- Trial name
- NCT05640375
- Testing
- Methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Baskent University
To Report the Rare Occurrence of Meckel's Diverticulum
The Uncommon Complications of Meckel's Diverticulum
Acas series study was conducted on emergency acute abdomen patients who finally confirmed intraoperatively as Meckel's diverticulum with different complications.
- Trial name
- MD (NCT05793385)
- Testing
- operative intervention
- Where
- Ethiopia
- Volunteers
- 4 people
- Sponsor
- Haramaya Unversity
Intussusception, Emergencies
Point-of-Care Ultrasonography for Intussusception
Pediatric emergency medicine (PEM) physicians are increasingly utilizing point-of-care ultrasound (POCUS). There is currently limited data regarding POCUS evaluation for intussusception in pediatric patients.
- Trial name
- NCT03360643
- Testing
- Point-of-care ultrasound prior to radiology ultrasound, Radiology-performed ultrasound
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Intussusception
Risk Factors for Recurrent Intussusception Successful Reduction in Pediatric Patients
To determine risk factors associated with recurrent intussusception among pediatric patients who have undergone successful reduction at a tertiary care hospital.
- Trial name
- NCT05259670
- Where
- 2 sites in Nepal
- Volunteers
- 78 people
- Sponsor
- Sanjeev Kharel
Gastroschisis, Anorectal Malformation
Children's Surgery in Sub-Saharan Africa
Background: Five billion people worldwide do not have access to safe, affordable surgical care. A significant proportion live in sub-Saharan Africa (SSA), where up to 50% of the population are children.
- Conditions
- Gastroschisis, Anorectal Malformation, Appendicitis, Intussusception
- Trial name
- PaedSurgAfrica (NCT03185637)
- Testing
- Various interventions for each of the conditions.
- Where
- United Kingdom
- Volunteers
- 1,407 people
- Sponsor
- King's College London
Intussusception
Laparoscopic Reduction of Intussusception in Children: Role in Primary Reduction After Failed Non-Surgical Therapies
Laparoscopic Reduction of Intussusception in Children: Role in Primary Reduction after Failed Non-Surgical Therapies.
- Trial name
- NCT06748326
- Testing
- Laparoscopy
- Volunteers
- 20 people
- Sponsor
- Assiut University
Intussusception
Study to Assess the Incidence of Intussusception in Children < 2 Years of Age in Singapore
This prospective study aims to estimate the incidence of intussusception among children < 2 years old through hospital-based surveillance in Singapore.
- Trial name
- NCT01177839
- Testing
- Screening sheets
- Where
- 5 sites in Singapore
- Volunteers
- 178 people
- Sponsor
- GlaxoSmithKline