Clinical trials: Intubation
Intubation, Intratracheal
Ultrasound Evaluation of Endotracheal Tube Depth
Correct positioning of the endotracheal tube (ETT) is crucial to ensure safe ventilation. To date, no test that can verify this right after intubation at the bedside exists.
- Trial name
- NCT01649882
- Testing
- US ETT (ultrasound endotracheal tube)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kai Schoenhage
Work Related Stress
Workload in Anesthesiological Practice
The study evaluates differences in perceived and objective workload in anesthetists during intubation procedure with a direct (Mcintosh) or indirect (Glidescope) laryngoscope.
- Trial name
- NCT04050241
- Testing
- Glidescope intubation, Mcintosh intubation
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Cardiac Catheterization, Endotracheal Tube
Ultrasound-detectable Endotracheal Tube: a Feasibility Study
The researchers are studying whether special features make it easier to see if the breathing tube is in the correct place. It is hoped that the investigational device will enable more accurate placement (depth and trachea vs.
- Trial name
- NCT05941013
- Testing
- Ultrasound detectable cuffed endotracheal tube (USD-ETT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- John R. Charpie
Airway Management, COVID19
The PAWS-COVID-19 (Pediatric AirWay complicationS COVID-19) Registry
The COVID-19 pandemic has disrupted anesthesia care all over the world. There remains very little data on current practice patterns and patient outcomes, particularly in anesthetized children.
- Trial name
- NCT04449042
- Testing
- airway management during sedation or general anesthesia
- Where
- United States
- Volunteers
- 14,835 people
- Sponsor
- Boston Children's Hospital
Intubation,Endotracheal
Pediatric Elective Intubation With and Without Muscle Relaxation Utilizing the Shikani Optical Stylet
The investigators' primary specific aims are to demonstrate that: 1. Pediatric patients with normal airways, undergoing elective surgical procedures, can be successfully intubated when deeply sedated, without the use of muscle…
- Trial name
- NCT00912990
- Testing
- Cisatracurium, Normal saline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Rady Children's Hospital, San Diego
Stress
Does the Presence of Observers Influence the Success of the Neonatal Endotracheal Intubation?
The Endotracheal intubation (ETI) of a neonate is a procedure that usually attracts a large number of observers. The fear of being judged by others could cause an increased level of stress, especially on the junior trainees.
- Trial name
- NCT02726724
- Testing
- 5 observers, 1 observer
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Airway Morbidity
What is the Gold Standard of Airway Management in the Anticipated Difficult Airway
A prospective Observationalstudie to analyze the current significance of the awake flexible endoscopy in German hospitals.
- Trial name
- FOI (NCT04158323)
- Testing
- Airway Management in patients with a anticipated difficult airway
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Paediatric Airway
Comparison of Time Taken for Intubation and Cormack Lehane View Between C-Mac With Glidescope Video Laryngoscopy in Paediatric Patients
This study compares the time taken to intubate between Cmac video laryngoscopy with Glidescope video laryngoscopy in paediatric patients aged 3-12 years old.
- Trial name
- NCT04145089
- Testing
- Glidescope video laryngoscopy/ C-MAC video laryngoscopy
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Hyaline Membrane Disease, Preterm Infant
Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GA
Hyaline membrane disease is one of the leading causes of morbidity and mortality in premature newborns in industrialized countries.
- Trial name
- PROPOSURF (NCT03721640)
- Testing
- electrocardiogram
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Videolaryngoscopy, Difficult Airway, Videolaryngoscopes
Comparison of PeDiAC and the Intubation Difficulty Scale in Pediatric Patients Intubated With Videolaryngoscopy
This prospective observational study aims to compare the effectiveness of the Paediatric Videolaryngoscopic Intubation and Difficult Airway Classification (PeDiAC) and the Intubation Difficulty Scale (IDS) in evaluating difficult…
- Conditions
- Videolaryngoscopy, Difficult Airway, Videolaryngoscopes, Airway Management Assessment, Pediatric Anesthesia
- Trial name
- VIDEOPED (NCT07141485)
- Where
- Turkey (Türkiye)
- Volunteers
- 430 people
- Sponsor
- Ankara City Hospital Bilkent
Hypertension, Laparoscopic Cholecystectomy
Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic Cholecystectomy
Dexmedetomidine provides better hemodynamic stability to the patients with hypertension undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04646317
- Testing
- Dexmedetomidine injection, Normal Saline
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Dr. Ruth K.M. Pfau Civil Hospital, Karachi
The Time Taken for Successful Tracheal Intubation in Each Technique
Orotracheal Intubation in Newborns: Videolaryngoscopy Vs Direct Laryngoscopy
The children were randomized into two groups to receive orotracheal intubation after anesthetic induction with neuromuscular blockade, either by direct laryngoscopy (DL, DL group) or by C-MAC video laryngoscopy (VL group)
- Trial name
- NCT06655168
- Testing
- Video Laryngoscopy, Direct Laryngoscopy
- Where
- Tunisia
- Volunteers
- 115 people
- Sponsor
- Tunis University
Intubation; Difficult or Failed
A.I. Supported Laryngoscopy and Endotracheal Intubation: a Manikin Study
LarynGuide is a newly developed AI-supported software for video laryngoscopy that supports the user through correct placement of endotracheal tube by means of audio-visual signals and warning of incorrect or potentially dangerous…
- Trial name
- aiTN (NCT06657417)
- Testing
- Video laryngoscopy, Video larnygoscopy
- Where
- Switzerland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Resuscitation
Newborn Ventilation in the Delivery Room: Could it be Improved With a T-piece Resuscitator?
A multicenter cross-over cluster randomized controlled trial protocol study in newborn infants ≥ 26 weeks gestational age requiring assisted ventilation (positive pressure ventilation [PPV]) for resuscitation in the delivery room…
- Trial name
- NCT00443118
- Testing
- T-piece resuscitator Neopuff TM, Self Inflating Bag with PEEP, Self Inflating Bag without PEEP
- Where
- 11 sites in United States, Argentina and 3 more
- Volunteers
- 1,032 people
- Sponsor
- Edgardo Szyld
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Airway Management, Tracheal Intubation
Curriculum for Airway Skills in Critically Ill Adults: a Delphi Evaluation
This study using a Delphi methodology, and involving international experts, will help define a training curriculum for physicians involved with airway management in critically ill patients.
- Conditions
- Airway Management, Tracheal Intubation, Critical Illness, Training
- Trial name
- CASCADE (NCT06689748)
- Testing
- Delphi procedure
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Hypoxemia
Neuromuscular-Blocking Agents and Hypoxemia During Intubation in Infants (ROC-HYPOX)
The prevention of the occurrence of respiratory events is a constant concern in pediatric anesthesia, as these represent the main cause of the anesthesic mortality.
- Trial name
- ROC-HYPOX (NCT02589691)
- Testing
- Rocuronium, Sodium chloride 0.9%
- Where
- 6 sites in France
- Volunteers
- 412 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Airway Aspiration, Cardiopulmonary Arrest
Benefit of the SALAD Technique on CPR Quality During Intubation in Contaminated Airway
Management of airways in contaminated environments can compromise the quality of cardiopulmonary resuscitation (CPR). This study examined the effectiveness of SALAD (Suction Assisted Laryngoscopy Airway Decontamination) compared…
- Trial name
- NCT06427655
- Testing
- SALAD intubation
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Congenital Diaphragmatic Hernia
Delayed Cord Clamping for Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with a high risk of mortality and need for life-saving interventions such as extracorporeal membrane oxygenation (ECMO), nitric oxide, and vasopressor…
- Trial name
- DING (NCT03314233)
- Testing
- DING
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia