Clinical trials: Intraocular Pressure
Glaucoma
Results of Mass Switch From Latanoprost to Travoprost
Prostaglandin analogs are a leading class of glaucoma drugs with a proven safety and efficacy for controlling IOP. They include latanoprost, bimatoprost, travoprost and unoprostone.
- Trial name
- NCT00347126
- Where
- Singapore
- Volunteers
- 372 people
- Sponsor
- Singapore National Eye Centre
Nuclear Cataract
Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)
To investigate the impact of high vs low Intraocular Pressure (IOP) on the intraoperative experience for the patient and surgeon.
- Trial name
- NCT06325397
- Testing
- High Intraocular Pressure (IOP), Low Intraocular Pressure (IOP)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Matthew Rauen
Posterior Capsule Opacification, Ocular Hypertension
Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy
To compare the efficacy of a Brinzolamide/Brimonidine fixed combination (FC) with Brimonidine 0.2% in preventing intraocular pressure (IOP) elevations after neodymium: yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy.
- Trial name
- NCT03192826
- Testing
- Brinzolamide/Brimonidine FC, Brimonidine 0.2%, Artificial tears
- Where
- Greece
- Volunteers
- 79 people
- Sponsor
- University Hospital of Patras
Pigmentary Dispersion Syndrome, Pigmentary Dispersion Glaucoma
IOP Reduction in Pigmentary Glaucoma Using DSLT
This study is a single-site, single-arm, prospective, observational study of IOP reduction after DSLT. Subjects will be assessed up to 12 months post-operatively.
- Trial name
- NCT07281391
- Testing
- Voyager DSLT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mann Eye Institute
Glaucoma, Cataract
Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase).
- Trial name
- FEMTOHTO (NCT02835482)
- Testing
- Femtolaser surgery, Phacoemulsification
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Intraocular Pressure
Effect of Sevoflurane Concentration on Intraocular Pressure in Surgical Children With Healthy Eyes
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01248689
- Testing
- concentration profile 1, concentration profile 2, concentration profile 3
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
ALL, Childhood, Steroid-Induced Glaucoma
Intraocular Pressure in Children With Acute Lymphoblastic Leukemia (ALL) Treated With High Dose Steroids
Childhood ALL patients are treated with high dose steroids. The study will follow the intraocular pressure of children treated in according to an AIEOP-BFM protocol, during the induction phase that will be compared to the…
- Trial name
- ALL (NCT04593745)
- Testing
- Intraocular pressure measurment
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Phacoemulsification
Clinical Analysis of Ocular Parameters Contributing to Intraoperative Pain During Standard Phacoemulsification
Charts of 142 patients who underwent standard phacoemulsification under topical anesthesia between March and August 2016 were reviewed.
- Trial name
- NCT03031652
- Testing
- Phacoemulsification
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Glaucoma, Open-Angle, Ocular Hypertension
A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
This is an observational study and will evaluate IOP reduction in newly diagnosed patients with POAG or OHT. All care (including treatment and diagnostic procedures) provided is at the discretion of the participating physicians…
- Trial name
- NCT01628614
- Testing
- Standard of Care
- Where
- Spain
- Volunteers
- 4,812 people
- Sponsor
- Allergan
Cardiovascular Diseases, Arteriosclerosis
Simplified Pulse Wave Velocity Measurement, Validation Study of the pOpmètre in Children
Arterial stiffness is an important marker of cardiovascular risk. It is measured by pulse wave velocity. The reference device to measure pulse wave velocity is the Sphygmocor which uses applanation tonometry.
- Conditions
- Cardiovascular Diseases, Arteriosclerosis, Atherosclerosis
- Trial name
- EPIPOP (NCT02991703)
- Testing
- pOpmètre®, Sphygmocor
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Nantes University Hospital
Congenital Glaucoma
Study Aim to Compare the Effect of Different Technique of Airway Managment During Anaesthesia on the Haemodynamics and Intraocular Pressure. Patients Were Divided Into Three Groups of 25 Patients Each. (Group A); Patients Who Were Subjected to LMA Insertion (Group B ).
this study aim to compare the effect of different technique of airway managment during anaesthesia on the haemodynamics and intraocular pressure in pediatric patient undergoing congenital glaucoma surgery.
- Trial name
- Airway and IOP (NCT07504315)
- Testing
- laryngeal mask insertion, I gel mask insertion, Endotracheal tube insertion
- Volunteers
- 75 people
- Sponsor
- Sohag University
Cleft Palate
Effect of Neck Extension on Intraocular Pressure in Patients Undergoing Palatoplasty
The purpose of this study is to investigate the change in intraocular pressure according to the neck extension during palatoplasty in pediatric patients.
- Trial name
- NCT04683978
- Testing
- Position
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Asan Medical Center
Intraocular Pressure
Effect of Raised End-Tidal pCo2 on Choroidal Volume
This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.
- Trial name
- NCT06275308
- Testing
- Ventilation manipulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Myopia, Anisometropia
Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment
Our study has three parts has three parts, and the main aim of the study is to find out if corneal hysteresis was associated with myopia or even a predictor of myopia poor control predictor: Part 1 of our study: patients with…
- Trial name
- NCT00658502
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Glaucoma, Cataracts
Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy
The purpose of this study is to compare the safety \& effectiveness of the two types of cataract and glaucoma surgeries. Results from this study may improve the surgical and post surgical management and long term management of…
- Trial name
- NCT00695747
- Testing
- 2 Site procedure- Phacoemulsification/IOL and Trabeculectomy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Lahey Clinic
Ocular Hypertension, Primary Open Angle Glaucoma
A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
This is a single-center, cross-over comparison parallel group randomized trial designed to evaluate the efficacy and safety of Ganfort compared to Duotrav for a treatment period of 8 weeks each.
- Trial name
- NCT01168414
- Testing
- Ganfort, Duotrav
- Where
- Malaysia
- Volunteers
- 42 people
- Sponsor
- Ministry of Health, Malaysia
Anesthesia, Intraocular Pressure
Establishment of an Anaesthetic Protocol for Examinations for Children With Glaucoma or Suspected Glaucoma
Correct measurement of the intraocular pressure of children with glaucoma or suspected glaucoma is essential for diagnosis and therapy.
- Conditions
- Anesthesia, Intraocular Pressure, Glaucoma, Suspect, Pediatric Glaucoma
- Trial name
- eyeBIS (NCT03972852)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Glaucoma, Intraocular Pressure
The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops
Pediatric glaucoma is a rare but potentially blinding condition where the pressure in the eye is too high. Diagnosis is based on intraocular pressure (IOP) and assessment of the optic nerve, cornea and other structures.
- Conditions
- Glaucoma, Intraocular Pressure, Anesthesia
- Trial name
- IOP (NCT01925391)
- Testing
- Tono-pen XL Applanation tonometer + Ocu-film +
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Miami
Vascular; Change, Dietary Modification
On-Line Intervention to Lower Cardiovascular Risk in Pediatric Heart Transplant Patients
Pediatric heart transplant patients have a high-risk cardiovascular profile affecting their long-term outcomes and survival. Currently, no effective cardiovascular preventative care is provided for this pediatric population, in…
- Conditions
- Vascular; Change, Dietary Modification, Physical Activity, Health Behavior
- Trial name
- NCT02519946
- Testing
- On-Line Diet and Exercise Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Stanford University
Peripheral Artery Tonometry, Diabetes
Peripheral Artery Tonometry in Children With Type 1 Diabetes and Obese Children
Background: The reactive hyperemia-peripheral artery tonometry (RH-PAT) is a newly developed method for noninvasive endothelial function assessment.
- Conditions
- Peripheral Artery Tonometry, Diabetes, Children, Obesity
- Trial name
- NCT01267591
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven