Clinical trials: Inflammatory Status
Inflammatory Bowel Disease
Nutritional Status and Body Composition in Childhood Inflammatory Bowel Disease
Malnutrition and growth retardation are common in children with inflammatory bowel disease (IBD), especially in Crohn's Disease (CD).
- Trial name
- NCT02704026
- Testing
- Assesment of nutritional status and body composition
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ankara University
Neonatal SEPSIS, Weight Gain
Effect of Early Feeding of Breast Milk
Breast milk is an extremely complex and highly variable biofliud that has evolved to nourish infants and protect them from disease whilst their own immune system matures.
- Conditions
- Neonatal SEPSIS, Weight Gain, Feeding Disorder Neonatal
- Trial name
- NCT03498989
- Testing
- preterm formula milk, exclusive breast milk
- Volunteers
- 100 people
- Sponsor
- Assiut University
Juvenile Idiopathic Arthritis
(1,3)-Béta-D-Glucan Levels at Diagnosis of Juvenile Idiopathic Arthritis and Its Correlation With Activity's Disease : a Cohort Sudy
Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disease of childhood. Most children still experience prolonged periods of active disease, however, there is still lack of effective and specific markers…
- Trial name
- BDG -JIA (NCT03984669)
- Testing
- The Juvenile Disease Activity Score (JADAS), (1-3)-ß-D-Glucan (BDG) assay (Fungitell)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Crohn Disease, Enteral Nutrition
Effect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Gastrointestinal Microbiota for Chinese Children With Crohn's Disease
Inflammatory bowel diseases (IBD) are chronic inflammatory diseases. It is believed that the inflammation results from sustained abnormal immune response towards altered or pathogenic microbiota in genetically susceptible hosts.
- Conditions
- Crohn Disease, Enteral Nutrition, Gastrointestinal Microbiome
- Trial name
- NCT03755583
- Testing
- Exclusive Enteral Nutrition
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Sepsis
Vitamin A Status in Critically Ill Children With Sepsis and Its Association With Illness Severity
The primary purpose of this study is to assess the status of vitamin A in critically ill children with sepsis and its association with the ill severity.
- Trial name
- NCT03598127
- Where
- China
- Volunteers
- 300 people
- Sponsor
- West China Hospital
Endothelial Dysfunction, Regulation of Acute Inflammatory Response
Endothelial Dysfunction and Selenium Status in Children With Acute Systemic Inflammatory Response
The overall hypotheses of this project is that severe sepsis is associated with endothelial dysfunction in pediatric patients and that selenium deficiency is associated with changes in biological markers of endothelial…
- Conditions
- Endothelial Dysfunction, Regulation of Acute Inflammatory Response, Selenium Deficiency
- Trial name
- NCT02619344
- Where
- Brazil
- Volunteers
- 114 people
- Sponsor
- Federal University of São Paulo
Inflammatory Bowel Diseases, Crohn Disease
Nutrition and Clinical Outcomes in IBD
The goal of this observational study is to demonstrate that nutritional status and body composition have an impact on clinical outcomes in inflammatory bowel disease (IBD). The main objectives are: 1.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Malnutrition
- Trial name
- NUTRICO-IBD (NCT06550310)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Barts & The London NHS Trust
Thyroid Disease, Irritable Bowel Disease
Study of Thyroid Status in Patients With IBD
. The aim of the present study is to study thyroid state in patients with IBD
- Trial name
- NCT05542368
- Testing
- Thyroid tests
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity, Metabolically Benign
Effect of Diet and Physical Activity on Adipokines
The prevalence of metabolic syndrome (MetS) in young population continues to rise. Obesity is a chronic inflammatory disorder in which leptin, adiponectin and C reactive protein (CRP) play an important role.
- Trial name
- NCT03435978
- Testing
- MetS+, MetS-
- Volunteers
- 66 people
- Sponsor
- Louis Turcanu Emergency Hospital for Children
Altered Mental Status, Sepsis
Pre-hospital Ventilation Clinical Study
This study will collect and characterize ventilator use during patient care with a ZOLL 731 Series ventilator in a pre-hospital setting.
- Conditions
- Altered Mental Status, Sepsis, Heart Failure, Hemorrhage
- Trial name
- NCT05604430
- Testing
- 731 Series Ventilator
- Where
- 5 sites in United States
- Volunteers
- 500 people
- Sponsor
- Zoll Medical Corporation
Healthy Infants, Infants With an Inflammatory Condition
Novel Isotope Dilution Technique to Assess Vitamin A Status
Background: There is no reliable method for vitamin A (VA) assessment for infants and young children. Serum VA concentration is not an authenticate indicator of VA status, while existing deuterium- VA isotope dilution methods to…
- Trial name
- NCT03000543
- Testing
- Vaccine
- Where
- 2 sites in Bangladesh
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Allergic Rhinitis
Effect of Laser Acupuncture Alone or Combined With Pranayama Exercise on Inflammation in Allergic Rhinitis
Allergic rhinitis (AR) represents one of the most common global health problems with seriously increasing incidence over the last decades.The goal of the treatment of rhinitis is to prevent or reduce the symptoms through…
- Trial name
- NCT05553483
- Testing
- pranayama plus acupoint stimulation by laser, acupoint stimulation by laser
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Septic Shock, Inflammation
Pharmacology of Exenatide in Pediatric Sepsis
Pharmacology of Exenatide in Pediatric Sepsis, PEPS is a phase 1-2 research study that will examine drug safety, drug metabolism, drug action and preliminary drug clinical effects of four does of exenatide injected every 12 hours…
- Conditions
- Septic Shock, Inflammation, Glucose Homeostasis, Organ Dysfunction
- Trial name
- PEPS (NCT01573806)
- Testing
- Exenatide, Exenatide vehicle
- Where
- United States
- Sponsor
- Seattle Children's Hospital
Cystic Fibrosis
Choline Nutrition in Children With Cystic Fibrosis (CF)
Cystic Fibrosis (CF) is a complex disease with a wide range of clinical problems. Despite enzyme replacement therapy, children with cystic fibrosis (CF) may still have problems absorbing some nutrients.
- Trial name
- NCT00686361
- Testing
- Choline supplementation
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of British Columbia
Cystic Fibrosis, Growth Failure
Baby Observational and Nutritional Study
Cystic fibrosis (CF) is a life-shortening disease that causes breathing and digestive problems, but can now be diagnosed at the time of birth. Lung function is very hard to measure in infants, but growth is not.
- Conditions
- Cystic Fibrosis, Growth Failure, Exocrine Pancreatic Insufficiency
- Trial name
- BONUS (NCT01424696)
- Where
- 28 sites in United States
- Volunteers
- 231 people
- Sponsor
- Seattle Children's Hospital
Septic Shock
Life After Pediatric Sepsis Evaluation
Sepsis represents the leading cause of childhood mortality worldwide. However, as distinct from adult medicine, there exists a large knowledge gap regarding long term health related quality of life (HRQL) and functional status…
- Trial name
- LAPSE (NCT01415180)
- Where
- 11 sites in United States
- Volunteers
- 389 people
- Sponsor
- Seattle Children's Hospital
Late Onset Neonatal Sepsis, Necrotizing Enterocolitis
Effects of Oral Probiotic Supplementation on the Clinical Status of Very-low-birth-weight Preterm Neonates.
The purpose of this study was to evaluate the safety of a probiotic foodstuff and its influence on emergence and development of natural intestinal flora and the clinical status of premature very low birth weight neonates.
- Conditions
- Late Onset Neonatal Sepsis, Necrotizing Enterocolitis, Infant, Very Low Birth Weight
- Trial name
- NCT02073214
- Testing
- Probiotic
- Volunteers
- 182 people
- Sponsor
- IBSS Biomed S.A.
Inflammatory Bowel Diseases, Psychosocial Impairment
Evaluation of Quality of Life and Psychosocial Status in Children With Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic condition that affects the psychosocial status and physical activities of children and their parents in many ways.
- Trial name
- NCT06270277
- Testing
- Pediatric Quality of Life Inventory (PedsQL), Strengths and Difficulties Questionnaire (SDQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hemorrhage
Hemostasis Achievement Reflecting Inflammatory Status of the Pulp Based on Cytokine Levels: A Cohort Study.
Assessment of pulp inflammation by hemostasis achievement after pulp exposure
- Trial name
- NCT03737682
- Testing
- ENzyme linked immunity-sorbet assays
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2, Pediatric Obesity
Association Between Irisin, Inflammatory Markers and Metabolic Status in Obese Children With Type 2 Diabetes Mellitus
The objective of this study was to investigate the association of irisin with inflammatory markers as well with metabolic and anthropometric parameters in children and adolescents with type 2 diabetes mellitus compared with…
- Trial name
- NCT03767608
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey