Clinical trials: Implementation Strategies
Evidence-Based Practices, CBT
A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy
This research project is a hybrid type 2 effectiveness-implementation trial that simultaneously examines (1) the effectiveness of a trauma-focused intervention for youth in the education sector and (2) the impact of a…
- Conditions
- Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
- Trial name
- NCT04451161
- Testing
- Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Washington
Goal-Setting
Feasibility of an Implementation Strategy for a Physical Activity Program in Rural Middle Schools
The investigators aim to build on the pilot study data looking at the feasibility of implementation of Goal Setting alongside Hoosier Sport at two schools (Eastern Greene Middle School and White River Valley Middle School).
- Trial name
- NCT07859033
- Testing
- Goal-Setting in Sport-Based Youth Development, No Goal-Setting Program
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Indiana University
Systemic Lupus Erthematosus (SLE)
Team-based Implementation of Hypertension Management in Childhood Lupus
The goal of this study is to compare the effectiveness of widely used implementation strategies to promote adherence to guideline-concordant evidence-based practices for monitoring and controlling blood pressure in patients with…
- Trial name
- ABOUT TIME (NCT07792733)
- Testing
- Health Navigator Engagement, Team Charter with Performance Monitoring, Pre-visit worksheet
- Volunteers
- 1,200 people
- Sponsor
- Boston Children's Hospital
Common Mental Disorders
Evaluating the Effectiveness of Multifaceted Implementation Strategies for Implementing a Guideline for the Prevention of Common Mental Disorders at the Workplace in Schools
Given today's high prevalence of common mental disorders and related sick leave among teachers an urgent need exists for a more sustainable working life for this professional group.
- Trial name
- NCT03322839
- Testing
- Multifaceted implementation strategies, Single implementation strategy
- Where
- Sweden
- Volunteers
- 732 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Substance Use Disorders, Opioid Use Disorder, Severe
EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy
This study is a multi-site, cluster randomized, two group implementation trial comparing a low- versus high-intensity implementation strategy for supporting hospital-based opioid use disorder treatment (HBOT) in community…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
- Trial name
- EXHITENTRE (NCT04921787)
- Testing
- Low Intensity, High Intensity
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Gavin Bart
Psychological Trauma, Mental Health
Collaborative Organizational Approach to Selecting and Tailoring Implementation Strategies
The purpose of this study is to partner with the North Carolina Child Treatment Program (NC CTP) and the SAMHSA-funded National Child Traumatic Stress Network (NCTSN) to develop and pilot the Collaborative Organizational Approach…
- Trial name
- COAST-IS (NCT03799432)
- Testing
- COAST-IS, TF-CBT Learning Collaborative
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pediatric Solid Tumors
Molecular Characterization of Genetic Alterations in Pediatric Solid Tumors
Background: In Argentina, central nervous system (CNS) solid tumors (19%) and non-CNS solid tumors (25%) account for 44% of pediatric tumors.
- Trial name
- NCT04773808
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Suicidal Self-directed Violence, Suicidal Preparatory Behavior
Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth
Scientific advances are constantly leading to better treatments. However, it is quite challenging for healthcare systems, including VA, to ask very busy providers to change the way they practice.
- Trial name
- MIDAS SPCT (NCT06011759)
- Testing
- Academic Detailing (AD), LEAP
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder, Leadership
Testing the LOCI Intervention
The project will develop knowledge on how managers can lead the implementation of practices that have proven to be effective for post-traumatic stress disorders (PTSD) in child and adult specialized mental health services.
- Trial name
- NCT03719651
- Testing
- LOCI, EMDR, CT-PTSD
- Where
- Norway
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Post Traumatic Stress, Overall Functioning
Randomized Controlled Trial of Supervision Strategies to Improve Clinician Fidelity to Trauma-focused CBT
The primary goal of this study is to examine the impact of varying supervision strategies on clinician fidelity and client outcomes in a community-based setting.
- Conditions
- Post Traumatic Stress, Overall Functioning, Clinician Fidelity, Supervision
- Trial name
- STEPS (NCT01800266)
- Testing
- Supervision Practices of TF-CBT
- Where
- United States
- Volunteers
- 1,280 people
- Sponsor
- University of Washington
Acute Respiratory Tract Infection
Evaluation of an Algorithm to Reduce Antibiotic Prescribing for Acute Bronchitis
Inappropriate use of antibiotics to treat patients with acute bronchitis is a significant factor contributing to the selection of antimicrobial drug resistant pathogens, which threaten the effectiveness of available therapies to…
- Trial name
- NCT00981994
- Testing
- Decision Support for ARI Management
- Volunteers
- 3,300 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Developing Screening Clinical Breast Examination Implementation Strategies in South Africa
The goal of this observational study is to engage with multilevel stakeholders to collaboratively and to systematically develop a suite of strategies for implementing breast cancer screening using clinical breast examination…
- Trial name
- NCT06233383
- Where
- South Africa
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Addiction, Mental Health Disorder
Using NIATx Strategies to Implement Integrated Services in Routine Care
This is an implementation research study designed to evaluate a defined strategy, NIATx, for its effectiveness in installing and sustaining evidence-based integrated services for persons with co-occurring substance use and mental…
- Trial name
- NCT03007940
- Testing
- Coach Site Visit, Walk-through, Learning Sessions
- Volunteers
- 49 people
- Sponsor
- University of Wisconsin, Madison
Latent Tuberculosis
Implementation of an Integrated Care Strategy for Children Contacts of Patients With Tuberculosis
Introduction: childhood tuberculosis continues to be a major public health problem, despite the fact that the visibility of the epidemic in this population group has increased, studies are still lacking that can resolve the gaps…
- Trial name
- NCT04331262
- Where
- Colombia
- Volunteers
- 163 people
- Sponsor
- Corporacion para Investigaciones Biologicas
Autism Spectrum Disorder
Iterative Redesign of a Multifaceted Implementation Strategy for a School-based Behavioral Skills Intervention (RUBI)
The increased prevalence of autism spectrum disorder (1 in 36 youth) in the United States along with the exorbitant cost of care of supporting one autistic individual with and without intellectual disability across their lifespan…
- Trial name
- NCT06508515
- Testing
- Unadapted Research Units in Behavioral Intervention (RUBI) implementation strategy, RUBI in Educational Settings (RUBIES)-Team
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- University of Washington
Developmental Language Disorder, Reading; Difficult
Promoting Caregiver Implementation of an Effective Early Learning Intervention
The goal of this study is to examine the impact of a caregiver-implemented shared reading program, Sit Together and Read (STAR), on children ages 4 to 5 with developmental language disorder.
- Trial name
- NCT06275815
- Testing
- Sit Together and Read (STAR), Monetary Reward, Text Encouragement
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Ohio State University
Asthma, Diarrhea & Vomiting
Best Strategies for Implementation of Clinical Pathways in Emergency Department Settings
An Ontario-wide study to identify best strategies to promote uptake of high quality, expert developed Clinical Pathways (CPs) within Emergency Departments.
- Trial name
- NCT01815710
- Testing
- Pediatric Asthma Clinical Pathway, Vomiting & Diarrhea Pathway
- Where
- Canada
- Volunteers
- 6,330 people
- Sponsor
- Children's Hospital of Eastern Ontario
Mental Health Disorder
Dissemination Strategies and Implementation Outcomes of Adolescent Character Strength Interventions.
The present research study will involve investigating the efficacy of large-scale dissemination models of evidence-based character strength interventions in secondary schools in Kenya.
- Trial name
- NCT05365503
- Where
- 3 sites in Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shamiri Institute
Influenza
Evaluation of an Influenza Vaccination Implementation Strategy for Hospital Health Care Workers
Influenza is a serious disease which can cause severe illness and even death among patients. Health care workers (HCWs) often get infected with influenza and up to 76% of them keep working while being ill.
- Trial name
- NCT01481467
- Testing
- Influenza vaccination implementation strategy
- Where
- 2 sites in Netherlands
- Volunteers
- 6 people
- Sponsor
- University Medical Center Groningen
Chronic Kidney Diseases
Validation, Implementation, and Cost-analysis of a Strategy for Personalized Diagnosis of Rare Kidney Diseases
Chronic kidney disease (CKD) affects about 10% of the world population, with high morbidity and mortality. Genetic kidney diseases are increasingly recognized across all age groups and represent over 20% of all the causes of CKD.
- Trial name
- NCT06324136
- Testing
- Implementation of the diagnostic algorithm
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS