Clinical trials: Hydronephrosis
Hydronephrosis, Hydronephrosis Congenital
Integrating an AI-Driven Hydronephrosis Decision-Making Tool
Hydronephrosis is a common congenital kidney anomaly. While most cases resolve on their own, some require surgery. Clinicians rely on repeated ultrasounds and sometimes invasive tests to decide if surgery is needed, but…
- Trial name
- NCT07581223
- Testing
- Machine learning model
- Volunteers
- 322 people
- Sponsor
- The Hospital for Sick Children
Congenital Hydronephrosis
Simplified Diagnostic Algorithm for Evaluation of Neonates With Prenatally Detected Hydronephrosis
Patients with congenital hydronephrosis will be identified by inpatient consultations performed by Dr. Assadi for congenital hydronephrosis and by outpatient problem lists with congenital hydronephrosis of Dr.
- Trial name
- NCT01330511
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rush University Medical Center
Congenital Obstructive Megaureter
Primary Obstructive Megaureter Management in Eastern Interregional Area
Congenital obstructive megaureter is a urinary malformation affecting the ureterovesical junction and causing obstruction to the flow of urine. It is the second most common cause of hydronephrosis.
- Trial name
- POMME (NCT05639283)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Hydronephrosis, Urinary Tract Infection
Effectiveness of Antibiotics Versus Placebo to Treat Antenatal Hydronephrosis
This study focuses on the relationship between prophylaxis antibiotics and frequency of urinary tract infection in children diagnosed with antenatal hydronephrosis.
- Trial name
- ALPHA (NCT01140516)
- Testing
- Trimethoprim, Simple Syrup
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- McMaster University
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hydronephrosis in Children
Ultrasonography Sensibilized by Oral Hydration and Hydronephrosis in Children.
Diagnosis and follow up of hydronephrosis is actually based on repeat ultrasonography and scintigraphy wich is a binding exam for children.
- Trial name
- NCT02086760
- Testing
- Ultrasonography with oral hydration, Scintigraphy
- Where
- France
- Sponsor
- University Hospital, Strasbourg, France
Hematuria, Hydronephrosis
Influence of Transmission Season on Outcome of Treatment of Schistosoma Haematobium Infection in Mozambique
To assess the influence of seasonal variations in Schistosoma haematobium transmission on treatment outcome (morbidity and re-infection)
- Trial name
- NCT00231322
- Testing
- praziquantel
- Where
- Mozambique
- Volunteers
- 520 people
- Sponsor
- DBL -Institute for Health Research and Development
Ureteropelvic Junction Obstruction
The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients
Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of hydronephrosis in pediatric ureteropelvic junction obstruction (UPJO) patients.
- Trial name
- NCT01711996
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yonsei University
Ureteropelvic Junction Obstruction
Long-term Outcome of Retroperitoneoscopic One-trocar-assisted Pyeloplasty: A Single-center and Single-surgeon Experience
Open surgical dismembered pyeloplasty has traditionally been the preferred method for treating ureteropelvic junction obstruction (UPJO), with a success rate exceeding 94%.
- Trial name
- NCT06349161
- Testing
- One-trocar-assisted pyeloplasty
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- National Children's Hospital, Vietnam
Hydronephrosis, Kidney Swelling
MRI Hydronephrosis Study
The purpose of this study is to compare a rapid noncontrast MRI protocol not requiring sedation to ultrasound in the assessment of hydronephrosis.
- Trial name
- NCT01588340
- Testing
- MRI (Magnetic resonance imaging), Ultrasound exam
- Where
- United States
- Sponsor
- University of Michigan
Bladder Function
Unilateral Cutaneous Ureterostomy - Long Term Follow up
This observational study is aimed at exploring bladder function following temporary unilateral low loop cutaneous ureterostomy carried out in newborns suffering from severe congenital hydro-ureteronephrosis
- Trial name
- ureterostomy (NCT00546208)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Urolithiasis, Ultrasonography
Emergency Department Targeted Ultrasound for the Detection of Hydronephrosis
An Emergency Department Targeted Ultrasound (EDTU) is an ultrasound examination performed by an emergency department physician, instead of a radiologist or ultrasound technician.
- Conditions
- Urolithiasis, Ultrasonography, Hydronephrosis
- Trial name
- NCT00555308
- Testing
- emergency department targeted ultrasound imaging
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Queen's University
Pediatric Disorder, Hydronephrosis in Children
Effect of Concomitant Bladder Neck Incision and Urethral Valve Ablation on Surgical Re-intervention Rate for Patients With Posterior Urethral Valve
To determine the short-term effects of concurrent valve ablation and bladder neck incision on re-intervention rate for patients with posterior urethral valve.
- Conditions
- Pediatric Disorder, Hydronephrosis in Children, Hydronephrosis, Secondary, Hydronephrosis Congenital
- Trial name
- NCT05087537
- Testing
- Valve ablation, Valve ablation and bladder neck incision
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Mansoura University
Hydronephrosis, Neurogenic Bladder
Alfuzosin Treatment in Children and Adolescents With Hydronephrosis of Neuropathic Etiology
Primary objective was to determine efficacy of Alfuzosin in the treatment of children and adolescents 2-16 years of age with newly diagnosed or progressive hydronephrosis due to elevated detrusor Leak Point Pressure [LPP] of…
- Trial name
- Alfahydro (NCT00576823)
- Testing
- Alfuzosin
- Where
- 12 sites in Bulgaria, Canada and 10 more
- Volunteers
- 25 people
- Sponsor
- Sanofi
Renal Colic, Hydronephrosis
Emergency Department Ultrasound in Renal Colic
Renal colic is a common (1300 visits per year at our institution) and painful condition caused by stones in the kidney and ureter, and can be mimicked by life threatening conditions such as a ruptured abdominal aortic aneurysm…
- Conditions
- Renal Colic, Hydronephrosis, Abdominal Aortic Aneurysm
- Trial name
- NCT01323842
- Testing
- EDTU
- Where
- Canada
- Volunteers
- 414 people
- Sponsor
- Queen's University
Hydronephrosis
Prospective Pediatric Pyeloplasty Robotic Surgical Database
Performance and outcomes measure are, at this time, relatively unknown for robotic pyeloplasty procedures. The purpose of this study is to provide a clearer understanding of the urology department's robotic pyeloplasty quality…
- Trial name
- NCT00882544
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Connecticut Children's Medical Center
Ureteral Obstruction
Urinary Biomarkers as Predictors on Renal Function in Congenital Hydronephrosis
The purpose of this study is to detect new urinary biomarkers that can be used as predictors on renal function in congenital hydronephrosis caused by unilateral ureteral obstruction (UUO) and to elucidate the pathophysiology of…
- Trial name
- NCT00568724
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pelviureteric Junction Obstruction, Pyeloplasty
Dismembered Pyeloplasty With and Without After Coming Stent
to compare outcome of pyeloplasty in pediatric population less than 6 months in age using an after coming stent versus stentless pyeloplasty.
- Conditions
- Pelviureteric Junction Obstruction, Pyeloplasty, Neonatal Hydronephrosis, Obstructive Uropathy
- Trial name
- NCT02138877
- Testing
- After coming stent after dismembered pyeloplasty, Stentless dismembered pyeloplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Congenital Hydronephrosis, UTD Grading System
Natural Course of Congenital Hydronephrosis in Infants Aged 0-6 Months
This project aims to systematically delineate the natural progression of congenital hydronephrosis diagnosed within the critical window of 0-6 months through a prospective, multicenter, observational cohort study.
- Conditions
- Congenital Hydronephrosis, UTD Grading System, Natural Progression, Pediatric
- Trial name
- NCT07382570
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine