Clinical trials: High Myopia
High Myopia
Screening and Identification of Biomarkers for High Myopia by a Rapid Method
To screen and identify sensitive biomarkers for high myopia via a robust, convenient, and cost-effective approach according to the association between high myopia and concentration of biomarkers in tear fluid, saliva and blood…
- Trial name
- NCT05803174
- Testing
- blood sample
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
The Role of SNP of ECM and MMP on the Development of Pathological High Myopia
To study the clinical characteristics and inheritance of pathological myopia in Taiwanese patients.
- Trial name
- NCT00172952
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
High Myopia, Gene Mutations
TGFB1 And LAMA1 Gene Polymorphisms in High Myopia
The investigators aimed to investigate TGFB1 and LAMA1 gene polymorphisms in children with high myopia in order to determine the genetic basis of large myopic shifts causing severe visual impairment and complications.
- Trial name
- NCT03451877
- Testing
- TGFB1 AND LAMA1 GENE POLYMORPHISMS
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Ege University
Myopia
Myopic Control for High Myopes Using Orthokeratology
The purpose of this study is to evaluate and compare the eyeball elongation in high myopic children using partial correction orthokeratology and single-vision spectacles.
- Trial name
- HM-PRO (NCT00977236)
- Testing
- Orthokeratology lenses, Single-vision spectacle lenses
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
High Myopia
Development and Pathological Changes of High Myopia Among Children and Adolescents in China
The study aims to observe the relationship between the changes of ocular structure parameters and pathological changes among children and adolescents with high myopia.
- Trial name
- NCT03533647
- Testing
- Observational
- Where
- China
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, High Myopia
Orthokeratology for High Myopia (OHM) Study
This project aims to investigate/examine high myopic subjects on full correction ortho-k (using Topaz ortho-k lenses for high myopia) compared to subjects undergoing partial reduction ortho-k and their relationship with myopia…
- Trial name
- NCT03881358
- Testing
- ortho-k lenses and thinner spectacles, newly designed ortho-k lenses
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
High Myopia, Axial Length
Repeated Low-Level Red-Light Therapy Shortens Axial Length
The purpose of this clinical trial is to investigate the incidence and magnitude of axial length shortening after repeated low-level red-light therapy in high myopia children and teenagers.
- Conditions
- High Myopia, Axial Length, Eye Diseases
- Trial name
- NCT05768152
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Age 3 to 16 Years (Inclusive), Male or Female, Clinical Diagnosis Confirming That Myopia Has Occurred in at Least One Eye
The Effectiveness and Safety of Low-intensity Single-wavelength Red Light in Controlling High Myopia in Children and Adolescents：A Randomized, Controlled, Multicenter Clinical Trial
Objective: To study the effectiveness and safety of low-intensity single wavelength red light in controlling high myopia in children and adolescents. Methods: Subject population: Children aged 3-16 years who have high myopia.
- Conditions
- Age 3 to 16 Years (Inclusive), Male or Female, Clinical Diagnosis Confirming That Myopia Has Occurred in at Least One Eye, The Guardian Voluntarily Signed the Subject's Informed Consent Form
- Trial name
- NCT05184621
- Testing
- Eyesing Redlight Instrument
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Refractive Error in Chinese Students
This cohort study aimed to assess the change of refractive status in Chinese school children.
- Trial name
- NCT05119543
- Testing
- outdoor time
- Where
- China
- Volunteers
- 36,452 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopic Choroidal Neovascularisation
OCTA Changes in Choroidal Neovascularization in High Myopia
To Analyze the Ability of Optical Coherence Tomography Angiography ( OCT-A ) to detect the presence of myopic Choroidal Neovascularization and to describe the structural features of Myopic CNV..
- Trial name
- NCT06357559
- Testing
- OCTA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
High Myopia
A Study on the Efficacy and Safety of Multi-focal Scleral Contact Lens
The rigid scleral contact lens with optical multi-focal design adopted in this study can focus the light in part of the optical area on the front of the retina to form myopic defocus, in order to delay the axial changes in…
- Trial name
- NCT05533450
- Testing
- Multi-focal rigid scleral contact lens, Rigid gas permeable contact lens
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Randomized Controlled Trials
Effect of a Myopia Prediction System on Myopia Prevention and Control
The global rise in myopia, particularly among children and adolescents in China, underscores the inadequacy of current prevention strategies, indicating that conventional screening and education alone are insufficient to curb the…
- Conditions
- Myopia, Randomized Controlled Trials, Artificial Intelligence (AI)
- Trial name
- NCT06633393
- Testing
- Feedback on Predicted High Myopia Risk at Age 18 Using the Myopia Prediction System, Feedback on Ophthalmic Examinations
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Early Intervention for High Risk Premyopic Children
The purpose of this research project is to add evidence of pharmacological (0.025% atropine) and optical (Defocus Integrated Multiple Segments Triple Enhanced Design spectacle lenses ) approaches for myopia prevention among…
- Trial name
- NCT07863713
- Testing
- 0.025% atropine eye drops, DIMS TED
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
High Myopia
Genetic Research on High Myopic Individuals in Northern China
HM, which can dramatically cripple the eyesight of those affected, is a rampant ophthalmic disorder around the globe. It is in recent years that substantial studies covering the relationship between distinct variations and HM…
- Trial name
- NCT06204211
- Testing
- ophthalmologic examinations
- Where
- China
- Volunteers
- 1,340 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
High Myopia, Refractive Errors
Repeated Low-Level Red-Light Therapy for Shortening Axial Length
The purpose of this clinical trial is to confirm the incidence and magnitude of axial length shortening after RLRL therapy in Chinese high myopia children and teenagers.
- Conditions
- High Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05550740
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Hyperopia
High Refractive Index Material 510(k)
The purpose of this study is to establish the substantial equivalence of the HDS HI 1.54™ to the paflufocon C material control lenses to correct myopia and hyperopia with and without astigmatism.
- Trial name
- PVS-07-07 (NCT00766168)
- Testing
- HDS HI 1.54; pahrifocon A, FluoroPerm 30 RGP; paflufocon C
- Where
- 8 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)