Clinical trials: Helminth Infections
Echinococcosis, Hepatic
Hypernatremia in Hydatid Cyst Treatment
Hypertonic saline (HS) is one of the most widely used scolocidal agents in the treatment of hydatid cysts. Hypernatremia is one of the complications associated with the use of HS.
- Trial name
- NCT05090020
- Testing
- Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Vitamin D Deficiency, Immunosuppression
Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT Study
Purpose: To examine whether helminth infection during pregnancy alters Vitamin-D-metabolism and reactivity of the child's immune system Hypothesis: Helminth infection during pregnancy is associated with altered Vitamin D levels…
- Trial name
- HELMVIT (NCT04324853)
- Testing
- Microscopy ( Urine filtration), UCAA test, qPCR,, Microscopy (Kato Katz, Coproculture, Harada Mori, MIF), qPCR,
- Where
- Gabon
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Mycobacterium Tuberculosis, LTBI (Latent TB Infection)
The Influence of Malnutrition, Diabetes Mellitus, and Helminth Infections on Biosignatures in Latent Tuberculosis in a South Indian Population
About 2 billion people worldwide are infected with tuberculosis (TB). Ninety percent of those people have latent TB infection (LTBI).
- Conditions
- Mycobacterium Tuberculosis, LTBI (Latent TB Infection), Malnutrition, Diabetes Mellitus
- Trial name
- NCT04526613
- Where
- India
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Onchocercal Subcutaneous Nodule, Epilepsy
Onchocerciasis-Associated Epilepsy, an Explorative Case-control Study
This is an exploratory case control study with the aim to compare the Onchocerca volvulus virome between persons with onchocerciasis-associated epilepsy (OAE) and persons with onchocerciasis but without epilepsy.
- Conditions
- Onchocercal Subcutaneous Nodule, Epilepsy, Virus
- Trial name
- NCT05868551
- Testing
- nodulectomy
- Where
- South Sudan
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Intestinal Parasitism
Mass Treatment T Solium Community Study
Investigators from Cayetano Heredia University and Johns Hopkins University are doing this study. They want to see how people and pigs get infected with a parasite, called cysticercus (known as "pig triquina").
- Trial name
- NCT00138359
- Testing
- Niclosamide
- Where
- Peru
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Schistosomiasis, Liver Fibrosis
Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis
Liver fibrosis is the most serious complication of schistosomiasis mansoni. However only limited proportion of subjects with infection develop this pathology and there is limited knowledge on risk factors for the differential…
- Conditions
- Schistosomiasis, Liver Fibrosis, Periportal Fibrosis, Oxidative Stress
- Trial name
- NCT01260012
- Testing
- Praziquantel+antioxidant suppl, Praziquantel+antioxidant
- Where
- Ethiopia
- Volunteers
- 414 people
- Sponsor
- Addis Ababa University
Ivermectin, Onchocerciasis
Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy
Many studies have reported an association between epilepsy, including Nodding Syndrome (NS), and onchocerciasis (river blindness).
- Conditions
- Ivermectin, Onchocerciasis, Epilepsy
- Trial name
- OAETREAT (NCT03052998)
- Testing
- Ivermectin
- Where
- Democratic Republic of the Congo
- Volunteers
- 91 people
- Sponsor
- Robert Colebunders
Schistosomiasis, Soil-Transmitted Helminthiasis
Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana
Schistosomiasis and soil-transmitted helminhtiasis occur throughout the developing world and are most prevalent in the poorest communitites.
- Trial name
- NCT00463931
- Where
- Ghana
- Volunteers
- 916 people
- Sponsor
- DBL -Institute for Health Research and Development
Healthy Volunteers
A Safety Study of Mebendazole in Children 2 to 10 Years of Age
The purpose of this study is to assess the safety and tolerability of mebendazole 500-mg chewable tablet formulation in a pediatric population.
- Trial name
- NCT01173562
- Testing
- Mebendazole
- Where
- Tanzania
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Hookworm
Efficacy and Safety of a Multi-dose Regimen of Mebendazole Against Hookworm in Children
This study is a double-blind randomized clinical trial which aims at providing evidence on the efficacy and safety of two regimens of mebendazole in school-aged children.
- Trial name
- NCT03245398
- Testing
- Treatment with one of the two regimens of mebendazole
- Where
- Tanzania
- Volunteers
- 186 people
- Sponsor
- Jennifer Keiser
Spleen; Cyst, Hydatid (Manifestation)
Splenic Surgery for Hydatid Spleen in Single Institutional Experience
Splenic-preserving surgery in hydatid spleen: Single intuitional experience
- Trial name
- NCT04890899
- Testing
- Cystic enculation of spleen hydatid
- Volunteers
- 10 people
- Sponsor
- Jabir Ibn Hayyan Medical University
Ascaris Lumbricoides Infection, Necator Americanus Infection
Cement flooRs AnD chiLd hEalth (CRADLE)
This randomized trial in rural Bangladesh will measure whether installing concrete floors in households with soil floors reduces child enteric infection.
- Conditions
- Ascaris Lumbricoides Infection, Necator Americanus Infection, Trichuris Trichiura; Infection, Diarrhea
- Trial name
- NCT05372068
- Testing
- Concrete household floor
- Where
- Bangladesh
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Stanford University
Helminthiasis
Assessment of Drug Efficacy of Local Albendazole
Infections with soil-transmitted helminthes (STH) occur throughout the developing world and remain a major public health problem in the poorest communities.
- Trial name
- NCT02420574
- Testing
- albendazole BENDEX, albendazole OVIS
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- University Ghent
Schistosomiasis
Assessment of Infection Activity in Travelers and Migrants Diagnosed With Chronic Schistosomiasis
The primary objective of this clinical investigation is to determine the percentage of travelers and migrants diagnosed with chronic schistosomiasis according to site-specific diagnostic practice who have active infection at the…
- Trial name
- SchistAct (NCT06873308)
- Testing
- UCP-LF CAA assay
- Where
- 8 sites in Belgium, Germany and 3 more
- Volunteers
- 278 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Soil-transmitted Helminth Infections
Community Health Education and Hygiene Promotion Added to Deworming Among Ethnic Khmer Children in Vietnam
This study evaluated whether adding community health education and household hygiene promotion to supervised deworming could improve soil-transmitted helminth (STH) outcomes and related caregiver and household factors among…
- Trial name
- NCT07855978
- Testing
- Albendazole 400 mg, Community Health Education and Hygiene Promotion
- Where
- 4 sites in Vietnam
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Hepatic Echinococcosis
Multimodal Imaging Diagnosis and Decision Aid System for Hepatic Echinococcosis Based on Image Omics and Vision Macromodel
Hepatic echinococcosis (hepatic echinococcosis) is an important zoonotic disease widely existing in the agricultural and pastoral areas of northwest China.
- Trial name
- NCT06540742
- Testing
- Artificial intelligence identifies liver hydatids
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Helminthiasis
Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults
The aim of this study is to provide data on the efficacy of oxfendazole against Trichuris trichiura at different doses in comparison to the standard single 400 mg dose of albendazole.
- Trial name
- NCT02636803
- Testing
- oxfendazole, albendazole
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Helminth Infection
Intestinal Microbiome Post-Azythromycin/Albendazole Treatment
Molecular testing of the gut microbiome and enteric pathogens is rapidly moving beyond targeted PCR testing to next generation sequencing techniques.
- Trial name
- NCT03032042
- Testing
- Azithromycin, Albendazole, Delayed treatment
- Where
- Ethiopia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neurocysticercosis
Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT
Comparing the effect of two different duration of same drug albendazole in patients with Neurocysticercosis less than or equal to 5 lesions on CT head at the end of 6 months.
- Trial name
- NCT02243644
- Testing
- 7 days of albendazole 15 mg/kg/day, 28 days of albendazole 15 mg/kg/day
- Where
- India
- Volunteers
- 97 people
- Sponsor
- All India Institute of Medical Sciences
Patients Who Underwent Surgury for Hydatid Cyst
The Current Study Aimed to Evaluate the Therapeutic Features and Complications of Liver Hydatid Cyst in Patients Who Underwent Surgery for CE in Fars Province, Southern Iran.
The current study aimed to evaluate the therapeutic features and complications of liver hydatid cyst in patients who underwent surgery for CE in Fars province, southern Iran.
- Trial name
- NCT04363151
- Testing
- No intervention.
- Where
- Iran
- Volunteers
- 293 people
- Sponsor
- Shiraz University of Medical Sciences