Clinical trials: Heart Failure Patients
Chronic Kidney Disease, Chronic Renal Failure
Karolinska Cardiorenal Theme-centre and StockholmHeartbank
Chronic kidney disease (CKD) affects 10-18% of the adult population and is becoming recognized as one of the most serious disorders causing increased risk for cardiovascular disease and death.
- Conditions
- Chronic Kidney Disease, Chronic Renal Failure, Acute Coronary Syndrome, Ischemic Heart Disease
- Trial name
- KKT (NCT01204645)
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Danderyd Hospital
Chronic Kidney Failure, Congenital Heart Defects
Chronic Kidney Disease in Teenagers With Congenital Cardiac Disease
The prevalence of chronic kidney injury (CKD) following cardiac surgery during childhood is not known, but there is evidence of CKD in young adults.
- Trial name
- PRECARDIO (NCT01845402)
- Testing
- blood and urine samples
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure, Hemodialysis
Empagliflozin in Heart Failure Dialysis Patients
Empagliflozin is not still approved for glomerular filtration rate < 20 cc/min/1.73m2. Considering the cardiac and renal benefits of this drug, the evaluation of the safety and efficacy of Empagliflozin for heart failure dialysis…
- Trial name
- NCT05967156
- Testing
- Empagliflozin10Mg Tab
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Heart Failure
Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF
The purpose of this study was to evaluate long-term safety and tolerability and to provide post-trial access to sacubitril/valsartan to eligible participants who successfully completed CLCZ696B2319 (PANORAMA-HF) core study Part 2…
- Trial name
- NCT03785405
- Testing
- sacubitril/valsartan
- Where
- 79 sites in United States, Argentina and 25 more
- Volunteers
- 216 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Heart Failure
Effects of Cardiac Sympathetic Blockade in Patients With Chronic Heart Failure
Although current pharmaceutical therapies have improved the survival rate in heart failure it remains a fatal disease and is associated with a poor 3-year survival.
- Trial name
- NCT02282618
- Testing
- Cardiac Sympathetic Blockade
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Harbin Medical University
Heart Failure
Is There a Benefit to Optimize Heart Failure (HF) Treatment in Aged Over 80 Year's Old Patients?
The purpose of this study is to determine if there is an interest to optimize HF (heart failure) management in patients over 80 years old.
- Trial name
- HF 80 (NCT01437371)
- Testing
- - Angiotensin conversing enzyme inhibitors: enalapril, captopril, lisinopril, ramipril, trandolapril.
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure
Ivabradine in Patients With an Unsatisfactory Percentage of Cardiac Resynchronization Therapy
The purpose of this study is to determine the role of ivabradine in cardiac resynchronization recipients with an unsatisfactory percentage biventricular pacing.
- Trial name
- IvaCRT (NCT02166060)
- Testing
- Ivabradine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Atrial Fibrillation, Heart Failure
NT-proBNP Measurements to Rule-out Heart Failure Among Patients With Atrial Fibrillation: A Prospective Clinical Study
This study aims to investigate N-terminal pro brain natriuretic peptide (NT-proBNP) as a biomarker to rule out heart failure in patients with atrial fibrillation. Atrial fibrillation and heart failure often co-exist.
- Trial name
- ProAF (NCT04125966)
- Where
- Denmark
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Heart Failure
Trial of an Interactive CD-Program on 6 Months Readmission Rate in Patients With Heart Failure
The purpose of this study is to determine whether extra education of patients with chronic heart failure can reduce 6 months readmission rate to hospital.
- Trial name
- NCT00311194
- Testing
- 6 months readmission rate to hospital
- Where
- Sweden
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Swedish Heart Lung Foundation
Congestive Heart Failure
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of…
- Trial name
- NCT01099982
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Cardiac Failure, Congestive Heart Failure
China National Heart Failure Registry
The purpose of CN-HF is to establish the national registration of hospitalized heart failure patients, evaluate and compare the clinical features and prognosis of diastolic and systolic heart failure, and find out the status of…
- Trial name
- CN-HF (NCT02079428)
- Testing
- No interventions
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Institute of Cardiovascular Diseases
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Heart Failure
"A Nurse-led Motivational Interviewing Tailored Intervention for Improving Self Care Behaviours and Health Outcomes in Heart Failure Patients in Oman
This is a pilot randomized clinical trial that have employed a motivational interviewing intervention to enhance self-care in heart failure patients.
- Trial name
- MITI (NCT07721909)
- Testing
- Motivational interviewing, Standard Care (Treatment as Usual)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University
Heart Failure
Telemedicine for Patients Suffering From Heart Failure (Danish Telecare North Trial)
There are two main aims in this study. The first objective is to evaluate whether a particular telehealth solution, in addition to standard treatment and care, lead to a significant decrease in the mortality and an increase in…
- Trial name
- TCN (NCT02860013)
- Testing
- Telemedicine
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Aalborg University
Heart Failure, Congestive
Enhancing Caregiver Support for Heart Failure Patients: the CarePartner Study
Informal caregivers, assisted by health information technology may help to fill the gaps in VA care management of heart failure patients by enhancing support for patients' treatment adherence, behavior changes, and symptom…
- Trial name
- NCT00555360
- Testing
- HITCM+CP, HITCM only
- Where
- 2 sites in United States
- Volunteers
- 372 people
- Sponsor
- US Department of Veterans Affairs
Chronic Stable Heart Failure
Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure
The purpose of this study is to evaluate the effects of spironolactone on circulating MMP levels and insulin resistance in patients with chronic heart failure.
- Trial name
- NCT00663195
- Testing
- spironolactone + furosemide
- Volunteers
- 16 people
- Sponsor
- Tottori University Hospital
Thyrotoxicosis
Thiamine Supplement in Patients With Severe Hyperthyroidism
Thyrotoxicosis is a hypermetabolic state in which there is increased utilization of thiamine. Thiamine deficiency has been observed in association with hyperthyroidism.
- Trial name
- NCT02767245
- Testing
- Thiamine
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Ramathibodi Hospital
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Systolic Heart Failure, Heart Failure With Reduced Ejection Fraction
Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response
This study aims to investigate whether the investigators can improve heart function in patients with heart failure who have undergone cardiac resynchronization therapy, but have not had an improvement in their heart function at…
- Conditions
- Systolic Heart Failure, Heart Failure With Reduced Ejection Fraction, CRT Non-Response, Left Bundle Branch Area Pacing
- Trial name
- NCT05884411
- Testing
- Left bundle branch area pacing, Cardiac MRI
- Where
- United States
- Sponsor
- VA Office of Research and Development
Heart Failure
Electronic Transmission of Laboratory and Adherence Records of Heart Failure Patients to General Practitioners Screen
Patients with heart failure (HF) need multiple guideline-directed medications to control the systolic and/or diastolic ventricular dysfunction.
- Trial name
- LabAdhDoc (NCT04326101)
- Testing
- Transmission of adherence records
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University Hospital, Basel, Switzerland