Clinical trials: Headache Disorders
Headache, Migraine, Migraine
Mind and Body Approaches to Pain Reduction in Youth With Migraine
The overarching objective of this protocol is to identify and understand the neural and pain processing mechanisms by which youth with migraine improve in response to preventive treatment.
- Conditions
- Headache, Migraine, Migraine, Migraine Disorders, Headache
- Trial name
- NCT03472092
- Testing
- Cognitive Behavioral Therapy (CBT), Amitriptyline, Biofeedback-Assisted Relaxation Training (BART)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine in Children, Migraine
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab
The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.
- Trial name
- NCT04537429
- Testing
- Eptinezumab
- Where
- 9 sites in United States
- Volunteers
- 28 people
- Sponsor
- H. Lundbeck A/S
Migraine Disorders, Headache, Migraine
Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pediatric Pain Population
The purpose of the research is to examine the outcomes of pediatric patients receiving Botulinum toxin type A (Botox ®) for the treatment of migraine.
- Conditions
- Migraine Disorders, Headache, Migraine, Pediatrics
- Trial name
- NCT03055767
- Testing
- OnabotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of California, Irvine
Hydrocephalus
Assessment of CSF Shunt Flow and Headaches With a Thermal Measurement Device
This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a study subject during headache and non-headache periods.
- Trial name
- NCT06996600
- Testing
- wireless thermal anisotropy measurement device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Rhaeos, Inc.
Stress Related Disorder, Musculoskeletal Pain
Immediate Effect of Energy Alignment and Mantra on Stress Related Pain in Adolescents
Psychiatrists have expressed concern at the emergence of education as a serious source of stress for school-going children - causing high incidence of deaths by suicide.
- Conditions
- Stress Related Disorder, Musculoskeletal Pain, Headache
- Trial name
- NCT03308630
- Testing
- Yoga based Energy Alignment and Mantra
- Where
- India
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Migraine
High School Start Time and Teen Migraine Frequency
Migraine is common in adolescents and can cause missed school and disability. The American Academy of Pediatrics (AAP) recommends that high schools start no earlier than 8:30 AM in order to accommodate the physiologic needs of…
- Trial name
- NCT03766412
- Testing
- High School start time
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of California, San Francisco
Migraine, Migraine in Adolescence
Mindfulness-Based Intervention for Adolescents With Chronic Migraine
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on…
- Trial name
- NCT06414109
- Testing
- BREATHE-Migraine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Migraine
Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment).
- Trial name
- NCT03275922
- Testing
- ZNS
- Where
- 47 sites in United States
- Volunteers
- 374 people
- Sponsor
- Impax Laboratories, LLC
Patent Foramen Ovale
Internal Microstructure of Patent Foramen Ovale Related to Stroke
This study aims to (1) investigate the internal microstructure of patent foramen ovale related to cryptogenic stroke, transient ischemic attack or migraine and determine the effectiveness of transcatheter closure in these…
- Trial name
- IMPORT (NCT04686253)
- Testing
- not appliable
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Migraine Headaches
Patent Foramen Ovale in Children With Migraine Headaches
This study will be the first to provide data about the relationship between PFO and migraine in children. By establishing the actual prevalence, we will better understand if PFO plays a role in the occurence of pediatric migraine…
- Trial name
- NCT00750594
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Utah
Sleep Initiation and Maintenance Disorders, Anxiety
HIRREM Developmental Study
The purpose of this study is to explore the functional and physiological effects associated with the use of High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), as supplemental care, for symptoms of…
- Conditions
- Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes
- Trial name
- NCT02709369
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Pseudotumor Cerebri
Pseudotumor Cerebri Headache Ten Years Outcome
Telephone interview on patient who suffered from PTC ten years ago regarding their headache status
- Trial name
- NCT06581185
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Headaches Chronic
Feasibility and Effectiveness of Home-behavioral Program for Adolescents With Migraine
Chronic Migraine and Migraine without aura at high frequency are disabling conditions also in adolescence age (2% of adolescents report chronic migraine) Common pharmacological treatments are often inadequate.
- Trial name
- Be-Home-Kids (NCT04604977)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Headache, Migraine
Adolescents With Migraine: What's Stress Got To Do With It?
The overall objective of this proposal is to better define the relationship between perceived stress, hair cortisol, and migraine in adolescents.
- Trial name
- Adostress (NCT02259387)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Migraine in Children, Sphenopalatine Neuralgia
SPG Block for Acute Pediatric Migraine
This is a randomized double blind trial comparing an intranasal sphenopalatine block with 2% lidocaine to intravenous (0.15 mg/kg, max 10mg) prochlorperazine in patients greater than 10 years of age presenting to a pediatric…
- Conditions
- Migraine in Children, Sphenopalatine Neuralgia, Migraine in Adolescence
- Trial name
- NCT03984045
- Testing
- Lidocaine topical, Prochlorperazine Injection
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Newark Beth Israel Medical Center
Headache, Tumor
Dexmedetomidine and Propofol for Pediatric MRI Sedation
The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia…
- Conditions
- Headache, Tumor, Seizure Disorder, Neurofibromatoses
- Trial name
- NCT03513757
- Testing
- propofol, Dexmedetomidine, Glycopyrrolate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Migraine, Acute Treatment of Migraine
Nerivio Efficacy by Time of Treatment Onset
This is a Post-marketing study investigating the impact of treatment time onset with Nerivio on the efficacy of Remote Electrical Neuromodulation (REN) for the acute treatment of migraine.
- Trial name
- NCT06976723
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 55,261 people
- Sponsor
- Theranica
Migraine
Pharmacokinetics & Safety of Cambia® in Migraine With or Without Aura in 12-17 Year Olds
Study Objectives: 1. The primary objective is to characterize the pharmacokinetics of a single oral administration of 50 mg Cambia in pediatric subjects, ages 12-17 years with a diagnosis of episodic migraine with or without…
- Trial name
- NCT02287376
- Testing
- Diclofenac Potassium for Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Depomed
Migraine
A Research Study To Compare Two Kinds Of Daily Headache
Chronic daily headache has been classified into several categories. One category is of sudden onset and is called New Daily Persistent Headache (NDPH).
- Trial name
- NCT00335803
- Where
- United States
- Sponsor
- Thomas Jefferson University
Hydrocephalus
Study of Ultrasound of the Eye for Children With Suspected Shunt Failure
The purpose of the study is to determine whether an ultrasound of the eye can be used as a radiation-free alternative to X-ray to identify children with risk of shunt failure in the Emergency Department.
- Trial name
- NCT00743457
- Testing
- Ocular Ultrasound
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Oregon Health and Science University