Clinical trials: Gastrointestinal Bleeding
Anemia, Small Bowel Bleeding
Tranexamic Acid for The Management of Bleeding Gastrointestinal Angioectasias
The goal of this clinical trial is to learn if oral tranexamic acid works to treat gastrointestinal angioectasias. It will also learn about the safety of tranexamic acid.
- Conditions
- Anemia, Small Bowel Bleeding, Angioectasias
- Trial name
- TAMBA (NCT07125508)
- Testing
- Tranexamic Acid (TXA) treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Stress Ulcers, Stress-related Mucosal Disease (SRMD)
China Survey of Stress Ulcer Bleeding in Critically Ill Neurosurgical Patients
Stress ulcers or stress-related mucosal disease (SRMD) is defined as "acute superficial inflammation lesions of the gastric mucosa induced when an individual is subject to abnormally elevated physiologic demands."[1] Studies have…
- Trial name
- SUP (NCT02316990)
- Where
- 11 sites in China
- Volunteers
- 1,416 people
- Sponsor
- AstraZeneca
Liver Cirrhosis, Gastrointestinal Bleeding
Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding
Can physiological indicators such as quick Sequential Organ Failure Assessment , Shock Index, and its derived indicators such as Modified Shock Index , Age Shock Index and Respiratory Adjusted Shock Index accurately predict the…
- Trial name
- SI (NCT06680583)
- Testing
- physical indicators such as shock index relatives
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- St. Martin De Porress Hospital
Neutral Temperature, Bloody Stool
Temperature of Extremities and Necrotizing Enterocolitis
Bloody stool and necrotizing enterocolitis(NEC) is two main focus in non-neonatal intensive care unit ward and usually lead to longed duration of hospitalization.
- Conditions
- Neutral Temperature, Bloody Stool, Necrotizing Enterocolitis
- Trial name
- NCT04801537
- Testing
- normal body temperature and warm extremities, normal body temperature and cold extremities
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Liver Cirrhosis, Portal Vein
Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis
The prevalence of portal vein thrombosis (PVT) in patients with liver cirrhosis is 5-20%. Current evidence regarding the effect of portal vein thrombosis on the prognosis of cirrhotic patients remains under debate.
- Conditions
- Liver Cirrhosis, Portal Vein, Venous Thrombosis, Varicose Veins
- Trial name
- NCT02335580
- Testing
- Somatostatin and its analogs, Endoscopic sclerotherapy, endoscopic variceal ligation, endoscopic tissue glue injection
- Where
- China
- Volunteers
- 475 people
- Sponsor
- General Hospital of Shenyang Military Region
Henoch-Schönlein Purpura, Gastrointestinal Injury
Mycophenolate Mofetil in Gastrointestinal Henoch-Schonlein Purpura
Henoch Schönlein purpura (HSP) is the most common type of vasculitis in children, with an incidence of ~10/100,000, whereas >90% of the patients develop symptoms at <10 years of age.
- Conditions
- Henoch-Schönlein Purpura, Gastrointestinal Injury, Mycophenolate Mofetil
- Trial name
- NCT05951517
- Testing
- MMF
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS)
Sirolimus for Autoimmune Disease of Blood Cells
Treatment for patients with autoimmune destruction of blood cells is poor. The part of the body that fights infections is called the immune system and white blood cells (WBCs) are part of the immune system.
- Conditions
- Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS), Evans Syndrome, Idiopathic Thrombocytopenic Purpura
- Trial name
- NCT00392951
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Philadelphia
Peptic Ulcer Hemorrhage
Effect of High-dose Oral Rabeprazole on Recurrent Bleeding After the Endoscopic Treatment of Bleeding Peptic Ulcers
This study is conducted to compare and evaluate the effect of administering a high-dose intravenous proton pump inhibitors or high-dose oral Rabeprazole in preventing recurrent bleeding after the endoscopic treatment of bleeding…
- Trial name
- NCT00838682
- Testing
- omeprazole sodium IV, Rabeprazole
- Where
- 2 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- The Catholic University of Korea
Gastrointestinal Hemorrhage
Pediatric Intensive Care Ulcer Prophylaxis Pilot Trial
This study tests the feasibility of a large study of stress ulcer prophylaxis in critically ill children. Children admitted to the Pediatric Intensive Care Unit who are expected to require mechanical ventilation for more than 48…
- Trial name
- PIC-UP (NCT02929563)
- Testing
- Pantoprazole
- Where
- 7 sites in Canada
- Volunteers
- 116 people
- Sponsor
- McMaster University
Colorectal Cancer
An Observational Study to Learn About the Medicine - BEVACIZUMAB BS [Pfizer] in Colorectal Cancer Patients From Japan.
The purpose of this study is to look at the safety of BEVACIZUMAB BS [Pfizer] when it was used to colorectal cancer patients in real-world clinical setting in Japan.
- Trial name
- NCT07527832
- Testing
- Bevacizumab-Pfizer Biosimilar, Avastin
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Pfizer
Bleeding Peptic Ulcer
Prevention of Gastric Ulcer Bleeding by Using "Computer-alert" in General Practice
The purpose of this study is to investigate if a computerised decision-support tool used in general practice, can reduce the frequency of peptic ulcer bleeding related to the use of NSAIDs (Non-Steroidal-antiinflammatory-drug)…
- Trial name
- NCT01845168
- Testing
- Computer-alert, A computer alerts which pops up when the GP presribes NSAID/ASA to a patient with risk-factors
- Where
- 2 sites in Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Transfusion Reaction, Transfusion Related Complication
Transfusion Surveillance in Anaesthesia
the aim of this register is to collect exhaustively the different data available surrounding a transfusion act in the context of an active haemorrhage.
- Conditions
- Transfusion Reaction, Transfusion Related Complication, Anesthesia, Anesthesia; Shock
- Trial name
- STAR (NCT06403163)
- Testing
- Transfusion
- Where
- Belgium
- Volunteers
- 50,000 people
- Sponsor
- Erasme University Hospital
Mucositis, Graft-versus-host Disease
Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX
A comparative trial where all patients will receive daily doses of tacrolimus (TAC) until day +60 when tapering will begin, in the absence of graft-versus-host disease (GVHD), and discontinued by day +180.
- Trial name
- NCT00360685
- Testing
- Tac+MTX, TAC + MMF
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Gastrointestinal Bleeding
Computed Tomography in Gastrointestinal Bleeding
Gastrointestinal bleeding represents a serious clinical problem and a common cause of hospitalisation with a mortality rate of 6-10% for upper Gastrointestinal bleeding and of 4% for lower Gastrointestinal bleeding requires a…
- Trial name
- NCT03243240
- Testing
- mutlidetector computed tomography
- Volunteers
- 30 people
- Sponsor
- Assiut University
Ulcerative Colitis
Bleach and Urine Color in UC Patients Using 5ASA
The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA
- Trial name
- Asableach (NCT06013696)
- Testing
- Adding household bleach to urine sample
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
Upper and Lower Gastrointestinal Bleeding
Clinical and Endoscopic Pattern in Children Presented With Upper and Lower Gastrointestinal Bleeding Insohag University Hospital
Gastrointestinal bleeding (GIB) is one of the most common conditions in the emergency department. Upper GIB is a major problem that has been decreasing over the past 20 years but still has high mortality rate.
- Trial name
- NCT06047873
- Testing
- Endoscopy
- Volunteers
- 30 people
- Sponsor
- Sohag University
Colon Cancer, Colorectal Cancer
Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?
Quantitative faecal immunochemical testing (qFIT) is used to test for blood within faeces that cannot always be visible. The presence of blood in the stool has been shown to be a finding where there may be a problem within the…
- Trial name
- NCT05329870
- Testing
- SNP array
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Early-Onset Sepses, Neonatal, Periventricular Haemorrhage Neonatal
Zinc Supplementation on Very Low Birth Weight Infant
Premature birth is a major cause of neonatal death in addition to neonatal asphyxia and infections. Early in life, premature babies must get aggressive nutrition so that there is no extrauterine growth restriction (EUGR) in the…
- Conditions
- Early-Onset Sepses, Neonatal, Periventricular Haemorrhage Neonatal, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
- Trial name
- NCT04050488
- Testing
- Zinc Sulfate
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Abdominal Pain, Inflammatory Bowel Diseases
Examining the Effect of Ondansetron on Bowel Prep Success
This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as assessing the impact on patient…
- Conditions
- Abdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, Diarrhea
- Trial name
- NCT05439772
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- State University of New York - Downstate Medical Center