Clinical trials: Gallbladder Diseases
Biliary Tract Cancer
Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer
This protocol for Varlitinib is developed for the treatment of Biliary Tract Cancer. Varlitinib (also known as ASLAN001) is a small-molecule, adenosine triphosphate competitive inhibitor of the tyrosine kinases - epidermal growth…
- Trial name
- TreeTopp (NCT03093870)
- Testing
- Varlitinib, Capecitabine
- Where
- 21 sites in United States, Australia and 9 more
- Volunteers
- 151 people
- Sponsor
- ASLAN Pharmaceuticals
Cholangiocarcinoma, Gallbladder Cancer
Avastin and Tarceva for Upper Gastrointestinal Cancers
Erlotinib and bevacizumab have shown activity individually, as single drugs, or in combination with chemotherapy in upper gastro-intestinal cancers, including esophageal and gastro-esophageal adenocarcinomas, gastric cancer and…
- Trial name
- NCT00350753
- Testing
- Erlotinib and bevacizumab
- Where
- 3 sites in Denmark
- Volunteers
- 126 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cholecystitis, Acute
Emergency Versus Elective Cholecystectomy in Acute Cholecystitis in the Era of Laparoscopy.
The aim of study is compare outcome of patients undergoing early laparoscopic cholecystectomy within 72 hours from the begging of symptoms to those of patients managed conservatively and operated late after 6-8weeks after the…
- Trial name
- NCT05502744
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Gallbladder Cancer
Artificial Intelligence-based Tumor Microenvironment Analysis for Prognosis Prediction in Gallbladder Cancer
This retrospective study aims to investigate the prognostic significance of artificial intelligence (AI)-powered analysis of tumor-infiltrating lymphocytes (TILs) and the tumor microenvironment (TME) in patients with resected…
- Trial name
- NCT07092397
- Where
- South Korea
- Volunteers
- 266 people
- Sponsor
- Samsung Medical Center
Cholecystitis, Acute, Elderly Infection
Percutaneous Transhepatic Cholangiography (PTHC) in Acute Cholecystitis and Clinical Outcomes
In a setting of acute cholecystitis (AC) one of the treatment option is percutaneous transhepatic cholangiography (PTHC) drainage.
- Conditions
- Cholecystitis, Acute, Elderly Infection, Drain Abscess
- Trial name
- NCT03087747
- Testing
- Percutaneous cholecystostomy
- Where
- Croatia
- Sponsor
- University of Split, School of Medicine
Gallbladder Cancer
Alcohol Consumption and Gallbladder Cancer
This case-control study matched by age and sex was performed to evaluate the region specific risk factors for gallbladder cancer in Jeju island, Korea.
- Trial name
- NCT02326948
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Cheju Halla General Hospital
Gallbladder Neoplasms
Irreversible Electroporation(IRE) For Unresectable Gallbladder Neoplasms
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Gallbladder Neoplasms.
- Trial name
- IRE (NCT02430662)
- Testing
- Irreversible electroporation (IRE), NanoKnife
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Pancreaticobiliary Reflux
Pancreaticobiliary Reflux in Patients Without Cholelithiasis
Pancreaticobiliary reflux has been found in patients with cholelithiasis and gallbladder cancer associated with normal pancreaticobiliary union.
- Trial name
- NCT00890201
- Testing
- Gallbladder bile sampling and intraoperative cholangiography
- Where
- Chile
- Volunteers
- 197 people
- Sponsor
- Cirujanos la Serena
Biliary Diseases, Pancreas Diseases
Single-operator Wire-guided Endoscopic Retrograde Cholangiopancreatography Cannulation Technique
The single-operator wire-guided cannulation technique doesn't require an experienced assistant and precise coordination between the assistant and endoscopist.
- Trial name
- NCT01598142
- Testing
- Team 1, Team 2
- Where
- China
- Volunteers
- 465 people
- Sponsor
- Qi-yong Li
Cholecystitis; Acute, Choledocholithiasis
Early MRI in Acute GallstonE Disease
This pilot study aims to determine the utility of direct Magnetic Resonance Cholangiopancreatography (MRCP) in the assessment of suspected acute gallstone disease presentations.
- Trial name
- E-MAGED (NCT03709030)
- Testing
- magnetic resonance cholangiopancreatography (MRCP)
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Perspectum
Infection
Ciprofloxacin Special Drug Use Investigation - To Investigate the Safety and Efficacy in Patients With Ciprofloxacin iv Administration Without Dilution
This study is a post-marketing surveillance in Japan to investigate the safety especially focusing on injection site adverse events and efficacy in patients with Ciprofloxacin iv administration without dilution in the daily…
- Trial name
- NCT01690559
- Testing
- Cipro (Ciprofloxacin, BAYQ3939)
- Where
- Japan
- Volunteers
- 704 people
- Sponsor
- Bayer
Dietary Habits
Dietary Factors and Risk of Gallbladder Carcinoma in China
The purpose of this study is to see how people's diets, other aspects of their lifestyles affect their chances of getting gallbladder carcinoma in China.
- Trial name
- DRGBC001 (NCT03546296)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yingbin Liu, MD, PhD, FACS
Gallstones
Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy
To explore the therapeutic effects for treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation and laparoscopic cholecystectomy.
- Trial name
- NCT01822262
- Testing
- minimally invasive cholecystolithotomy with gallbladder reservation, laparoscopic cholecystectomy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chengyi Sun
Gallbladder Volvulus
Gallbladder Volvulus Diagnosed Intraoperatively: Case Report
85-year-old female patient presented with right upper quadrant pain of one day duration, diagnosed with acalculous cholecystitis, and intraoperatively diagnosed with gallbladder volvulus.
- Trial name
- NCT06050876
- Testing
- Laparoscopic cholecystectomy for gallbladder volvulus
- Where
- Lebanon
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Balamand
Cholecystitis, Chronic
Bikini Scarless Laparoscopic Cholecystectomy for Morbid Obesity as a Day Case.
Background: Bikini line laparoscopic cholecystectomy is a safe method, used as a scarless cosmetic port technique for gall bladder diseases in morbid obese patients as a day case.
- Trial name
- NCT04836598
- Testing
- laparoscopic cholecystectomy
- Where
- 4 sites in Egypt, Saudi Arabia
- Volunteers
- 3 people
- Sponsor
- Zagazig University
Cholelithiasis, Gall Stone
Bile Composition in Healthy and Gallstones Patients
Determine differences between lithogenic and non-lithogenic bile composition.
- Conditions
- Cholelithiasis, Gall Stone, Gall Bladder Disease
- Trial name
- NCT03981315
- Testing
- Bile test, Blood test, Gall stone study
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Hospital Son Espases
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma
Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery
This randomized phase II trial studies how well trametinib or combination chemotherapy works in treating patients with refractory or advanced biliary or gallbladder cancer or that cannot be removed by surgery.
- Conditions
- Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma, BCLC Stage C Adult Hepatocellular Carcinoma, BCLC Stage D Adult Hepatocellular Carcinoma
- Trial name
- S1310 (NCT02042443)
- Testing
- Capecitabine, Fluorouracil, Laboratory Biomarker Analysis
- Where
- 295 sites in United States
- Volunteers
- 53 people
- Sponsor
- National Cancer Institute (NCI)
Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis
Laparoscopic Cholecystectomy Using Airseal in Children
The goal of this observational study is to compare the use of Airseal versus a standard insufflation, in children who underwent laparoscopic cholecystectomy, between January 2021 and December 2022.
- Conditions
- Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis, Pancreatitis Due to Gallstones, Child, Only
- Trial name
- VBAS (NCT06734507)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Destinval Christelle
Adenocarcinoma of the Extrahepatic Bile Duct, Adenocarcinoma of the Gallbladder
S0514 Sorafenib in Treating Patients With Unresectable or Metastatic Gallbladder Cancer or Cholangiocarcinoma
This phase II trial is studying how well sorafenib works in treating patients with unresectable or metastatic gallbladder cancer or cholangiocarcinoma.
- Conditions
- Adenocarcinoma of the Extrahepatic Bile Duct, Adenocarcinoma of the Gallbladder, Adenocarcinoma With Squamous Metaplasia of the Gallbladder, Cholangiocarcinoma of the Extrahepatic Bile Duct
- Trial name
- NCT00238212
- Testing
- sorafenib tosylate, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)