Clinical trials: Fluid Responsiveness
Circulatory Failure, Shock State
Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children
In this study of diagnostic accuracy, the investigators aim to validate a faster, simpler, and noninvasive test of fluid-responsiveness in critically ill children.
- Conditions
- Circulatory Failure, Shock State, Fluid Therapy
- Trial name
- FAST (NCT07522580)
- Testing
- validation a test of fluid-responsiveness in critically ill children
- Where
- 4 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Bordeaux
Pediatric ALL
Prone Fluid Responsiveness in Children
In pediatric patients in the prone position, the reliability of pulse pressure variation and stroke volume variation, and pleth variability index to predict fluid responsiveness have not previously been established.
- Trial name
- NCT05449886
- Testing
- TVC
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Shock
Predicting Fluid Responsiveness During Shock in Newborns and Infants by End-expiratory Occlusion Test
To date, the end-expiratory occlusion test in infants or children has never been evaluated as a marker of preload dependence. It therefore appears clinically relevant to evaluate this new indicator to predict fluid responsiveness…
- Trial name
- EVEOC (NCT04932590)
- Testing
- End-expiratory occlusion test
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Shock
Tissue Perfusion Pressure for Predicting Fluid Responsiveness in Patients With Shock
This prospective observational study aims to evaluate the ability of tissue perfusion pressure (TPP) to predict fluid responsiveness in critically ill patients with shock and tissue hypoperfusion.
- Trial name
- NCT07670390
- Testing
- When the attending physician determines that fluid resuscitation is clinically indicated: Patients will remain in the supine position. Crystalloid solution will be administered intravenously via centr
- Volunteers
- 34 people
- Sponsor
- Jingyuan,Xu
Atrial Septal Defect
A Prospective Investigation of Pleth Variability Index (PVI) as a Dynamic Parameter of Fluid Responsiveness in Children
This study is designed to investigate the ability of pleth variability index (PVI) to non-invasively predict fluid responsiveness in mechanically ventilated children.
- Trial name
- NCT02276599
- Testing
- Volume expansion
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Brian Schloss
Hypovolemia
Fluid Responsiveness Using Forehead Sensor in Children
Forehead sensor can predict the more accurate fluid responsiveness than finger sensor in children
- Trial name
- forehead (NCT03132480)
- Testing
- fluid resuscitation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Plasma Volume, Tidal Volume
Effect of Tidal Volume Change on Pressure-based Prediction of Fluid Responsiveness in Children
This study evaluates predictability of fluid responsiveness of pressure-based dynamic variables such as pulse pressure variation and systolic pressure variation, according to tidal volume change in patients undergoing cardiac…
- Trial name
- NCT03963089
- Testing
- Tidal volume_6mL/kg, Tidal volume_10mL/kg, Tidal volume_14mL/kg
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Septic Shock
Carotid Doppler and EEOT for Fluid Responsiveness Prediction
Fluid responsiveness prediction prior to fluid challenge administration is a topic of interest, which has been extensively investigated, but remains challenging.
- Trial name
- NCT04470856
- Testing
- End-expiratory occlusion test (EEOT)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anesthesia, Intravenous Fluid
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.
- Conditions
- Anesthesia, Intravenous Fluid, Blood Pressure
- Trial name
- NCT03431064
- Testing
- Lung Recruitment Maneuver, Fluid Administration
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston Children's Hospital
Liver Cirrhosis
Dynamic Preload Parameters During Liver Transplantation
The arterial system compliance is compromised in liver cirrhotic patients. Dynamic preload variables are either pressure-based (e.g.pulse pressure variation; PPV), flow-based (e.g.
- Trial name
- NCT01971333
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Anesthesia, Fluid Responsiveness
RPVI for Fluid Responsiveness in Children
The purpose of this study is to validate Rainbow pleth variability index for prediction of fluid responsiveness in children.
- Trial name
- NCT05601622
- Testing
- Fluid loading, Transthoracic echocardiography, PVI, RPVI
- Volunteers
- 45 people
- Sponsor
- Seoul National University Hospital
Circulatory Failure, Shock State
Fluid Responsiveness Assessment in Children
Fluid responsiveness assessment is a major issue in intensive care. Since fewer fluid responsiveness tests can be used children, fluid expansion prescriptions are often based on professional practices due to the absence of…
- Trial name
- FRAICHE (NCT07073859)
- Testing
- Fluid expansion
- Where
- 31 sites in France
- Volunteers
- 513 people
- Sponsor
- University Hospital, Bordeaux
Circulatory Failure / Shock State, Fluid Therapy
Metabolic Fluid Responsiveness in Children
The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery.
- Trial name
- METAFRIC (NCT07255469)
- Where
- 8 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Bordeaux
VCO2 Variation in Intensive Care as a Marker of Fluid Responsiveness, Cardiac Index Variation Transpulmonary Thermodilution in Patients on Controlled Ventilation With Shock
Cardiac Responsiveness Assessment by CO2
The increase of cardiac output resulting from increased blood volume (systolic ejection volume) during intravenous fluid administration defines a state of fluid responsiveness.
- Trial name
- CRAC (NCT05430880)
- Testing
- impact of fluid challenge on the cardiac index and CO2 respiratory parameters analysis (VCO2, EtCO2)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Hypovolemia
Prediction of Fluid Responsiveness in Children With Single Ventricle
The purpose of this study is to evaluate predictability of an abdominal compression-induced change of blood pressure for fluid responsiveness in children with single ventricle (bidirectional cavopulmonary shunt and Fontan tract).
- Trial name
- NCT02826135
- Testing
- abdominal compression
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Hypovolemia, Hemorrhage
Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients
The Pressure Recording Analytical Method, invasive hemodynamic monitoring, is an uncalibrated pulse contour analysis, installed in the Mostcare® system that allows a continuous estimation of the stroke volume and thus the cardiac…
- Conditions
- Hypovolemia, Hemorrhage, Fluid Responsiveness
- Trial name
- MOSTCARE-PED (NCT04186416)
- Testing
- Mostcare® device, Transthoracic cardiac ultrasound
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Premature Baby 26 to 32 Weeks, Premature Baby 33 to 36 Weeks
Fluid Responsiveness Evaluation by a Non-invasive Method in Children, Extended to PREterm Infants - FRENCH-PREMA
In this study, the investigators aim to validate a non-invasive marker of fluid-responsiveness in preterm infants (term below 37 gestational week) with acute circulatory failure based on standardized abdominal compression.
- Trial name
- FRENCH-PREMA (NCT06287710)
- Testing
- Non interventional study (study of diagnostic accuracy with an extra echocardiographic assessment).
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Circulatory Failure
Fluid Responsiveness Evaluation by AbdomiNal Compression in Kids Based on the STARLING Concept
Purpose: Fluid responsiveness in a context of circulatory failure can be predicted by different way. Dynamic criteria such as pulse pressure variation, stroke volume variation during an end-expiratory occlusion maneuver or a…
- Trial name
- FRANCK (NCT02505646)
- Testing
- Observational study. No special intervention will be made
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hopital Louis Pradel
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sepsis, Septic Shock
IVC Collapsibility Index or CVP as a Predictor of Fluid Responsiveness in Pediatric Sepsis
Pediatric population who suffered from sepsis due to perforated viscus will receive fluid resuscitation guided by either central venous pressure or guided by IVC collapsibility index.
- Conditions
- Sepsis, Septic Shock, Perforated Viscus, Hospitalism in Children
- Trial name
- NCT06833333
- Testing
- Central venous catheter, IVC collapsibility index
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University