Clinical trials: Environment
Type 1 Diabetes
T1D Risk Assessment in Kids With Relatives
The purpose of this study is to determine whether early immunological markers (activation of autoreactive T lymphocytes) precede and are predictive of the appearance of autoantibodies in children born from type 1 diabetic parents.
- Trial name
- TRAKR (NCT02184676)
- Testing
- Analysis of early immune modifications, Collection of clinical and socio-demographic data
- Where
- France
- Volunteers
- 512 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Autism, Developmental Disabilities
Childhood Autism Risks From Genetics and the Environment (The CHARGE Study)
The purpose of this study is to understand how genes, environment, and the interplay between the two, influences the development of autism and other neurodevelopmental disorders.
- Trial name
- NCT00106652
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Diarrhea, Waterborne Disease
Trial of Safe Water Storage Among People Living With HIV
Environmental health-related pathogens include faecal-oral, diarrhoeagenic microbes that may be transmitted via drinking water and are related to sanitation and hygiene.
- Conditions
- Diarrhea, Waterborne Disease, HIV
- Trial name
- NCT01376336
- Testing
- Safe storage device
- Where
- Zambia
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Psychotic Disorders, Anxiety
A Study of Dose-response Relationship and the Evidence Based Multisensory Stimulation Intervention
Design: This parallel randomized controlled trial (RCT) was conducted according to the Consolidated Standards of Reporting Trials (CONSORT).
- Conditions
- Psychotic Disorders, Anxiety, Complementary Therapies, Clinical Trial
- Trial name
- NCT05012709
- Testing
- multisensory stimulation therapy
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Jianan Psychiatric Center, Ministry of Health and Welfare
Pediatric Obesity, Sedentary Behavior
Childcare Outdoor Learning Environments as Active Food Systems
The aim of this project is to assess the effectiveness of the fruit and vegetable (FV) gardening component of the Preventing Obesity by Design strategy to support preschool fresh fruit and vegetable knowledge, liking and…
- Trial name
- COLEAFS (NCT04864574)
- Testing
- Garden installation
- Where
- 15 sites in United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Puberty, Precocious, Breast
Early Breast Growth in Girls Aged 6 to 8 Years in the Current Environmental Context
Various studies show an increase in the number of cases of early puberty in girls with breast development with a variable clinical presentation and evolution. This increasing phenomenon concerns girls between 6 and 8 years old.
- Conditions
- Puberty, Precocious, Breast, Environmental Exposure
- Trial name
- PENELOPE (NCT06083415)
- Testing
- Environmental health measures
- Where
- 2 sites in France
- Volunteers
- 62 people
- Sponsor
- Lille Catholic University
Body Composition, Executive Functioning
Early Genetic and Environmental Influences on Eating - The Baylor Infant Twins Study
The purpose of this study is to better understand the genetic and environmental etiology of early infant effortful control and infant feeding behaviors, and preschool executive functioning and eating behaviors.
- Conditions
- Body Composition, Executive Functioning, Temperament
- Trial name
- BITS (NCT04306523)
- Testing
- Observation
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Covid19, SARS-CoV Infection
COVID-19 in Polish Ice Swimmers.
Ice swimming is an increasingly common phenomenon in Poland. It has been confirmed that it has a beneficial effect on health by increasing the natural non-specific immunity to infections.
- Conditions
- Covid19, SARS-CoV Infection, Resistance, Disease, Hypothermia
- Trial name
- ICE (NCT04817280)
- Testing
- Ice Swimming
- Where
- 3 sites in Poland
- Volunteers
- 2,534 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Healthy
Preventive Medicine Study of Childhood Atopic Diseases
Under environmental intervention programs, to explore the associations between Environmental Tobacco Smoke (ETS) and changes of pulmonary function, cytokines and new-onset asthma between different groups.
- Trial name
- NCT00960596
- Testing
- Health promotion and health education for smoking habits
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy (CP), Motor Disability
Complex Rehabilitation Technology Enabled Physical Activity for Children With Motor Delays Via Telehealth in Natural Environments
The primary goal of CP-MOVES is to evaluate 1) the preliminary efficacy of a telehealth-delivered, parent coaching intervention in the use of adaptive standers, on physical activity, sleep, and endurance in young children with…
- Conditions
- Cerebral Palsy (CP), Motor Disability, Motor Delay
- Trial name
- CP-MOVES (NCT07252713)
- Testing
- Stander Use
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Bipolar Disorder, Schizophrenia
Immuno-Genetic, Inflammation, Retro-Virus, Environment
Immunology combined to neurobiology now offer prominent tools to yield biomarkers, so far missing in psychiatry, and to design innovative treatment approaches based on the discovery of new molecular and cellular targets.
- Trial name
- I-Give (NCT02878408)
- Testing
- Blood sampling
- Where
- 6 sites in France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Pr. Marion Leboyer
Exposure, Health Behavior
Advancing Tools for Human Early Lifecourse Exposome Research and Translation- Adolescence Follow-up of the HELIX Subcohort
ATHLETE will set up a prospective Europe-wide exposome cohort covering the first 2 decades of the life course, which will integrate data on the external, chemical, physical,behavioral, and social domains of the exposome, as well…
- Conditions
- Exposure, Health Behavior, Environment
- Trial name
- ATHLETE (NCT05158010)
- Testing
- HELIX's follow-up
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Autism
Sensory Adapted Dental Environment to Enhance Oral Care for Children With ASD
The goal of this project is to collect information that will support a later clinical trial on the effectiveness of a specially adapted dental environment for children who have difficulty tolerating oral care in the dental…
- Trial name
- SADE (NCT02077985)
- Testing
- Sensory Adapted Dental Environment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diarrhea, Infantile, Infection Gastrointestinal
PAthogen Transmission and Health Outcome Models of Enteric Disease
The objective of the PATHOME study is to (1) develop statistical and computational methods for examining a complex disease system of interactions between and amongst children, animals, the environment, and enteric pathogens and…
- Conditions
- Diarrhea, Infantile, Infection Gastrointestinal, Stunting, Wasting
- Trial name
- PATHOME (NCT05322655)
- Where
- Kenya
- Volunteers
- 286 people
- Sponsor
- State University of New York at Buffalo
Oral Feeding Outcomes, Neurodevelopment Outcome
Impact of Hospital to Home: Optimizing Preterm Infant Environment for Surgical Neonates and Their Parents (H-HOPE)
Infants born with congenital defects may require major surgery in the neonatal period. These infants are at risk for neurodevelopmental impairments.
- Trial name
- H-HOPE (NCT07372898)
- Testing
- H-HOPE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Feng Shui
Feng Shui And Emotional Response in the Critical Care Environment Study
Objective: To assess whether the feng shui of critical care bed spaces affects the inner harmony of nursing staff Design: Prospective cohort study Setting: Doncaster critical care department Participants: Critical care nursing…
- Trial name
- FARCE (NCT03265587)
- Testing
- No intervention
- Volunteers
- 408 people
- Sponsor
- Doncaster And Bassetlaw Hospitals NHS Foundation Trust
Food Allergy in Children
Friends, Family & Food: Food Allergy App for Youth - II
Objective: This Phase II STTR grant incorporated user feedback collected in an earlier development project to build interactive, web-based software that helps children with food allergies learn about their condition and gain…
- Trial name
- F3A-App (NCT05111938)
- Testing
- Friends, Family, and Food App (F3A-App)
- Volunteers
- 80 people
- Sponsor
- Rhode Island Hospital
Family Relations, Blight
Community Health Through Engagement and Environmental Renewal
Community Health from Engagement and Environmental Renewal (CHEER) will leverage previous Centers for Disease Control and Prevention (CDC) community engagement projects to reach and intervene on a high need population.
- Trial name
- CHEER (NCT04362475)
- Testing
- Community Health through Engagement and Environmental Renewal (CHEER)
- Where
- United States
- Volunteers
- 915 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cochlear Implants, Child Language
The Relationship Between Phonological Awareness Skills And Home Environment Literacy in Cochlear Implant Users
The aim was to examine the relationship between home literacy of parents whose has children who use cohlear implant and family demographic characteristics and phonological awareness skills of children with cochlear implant.
- Conditions
- Cochlear Implants, Child Language, Literacy, Phonological (Speech) Disorder
- Trial name
- NCT06322472
- Testing
- The Turkish Early Language Development Test (TEDIL), The Family Literacy Scale, The Early Childhood Phonological Sensitivity Scale (PASECP)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Uskudar University