Clinical trials: Endometriosis
Endometriosis, Apoptotic Pathway Deregulation
Serum Caspase 3, Annexin a2 and Soluble Fas Levels and Endometriosis
The study population will comprise of 90 women age varying between 15-55 years, those are candidate for laparoscopic surgery due to definition of >4 cm endometrioma or any other benign ovarian cysts such as mature teratoma or…
- Trial name
- NCT03020108
- Testing
- Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Endometriosis, Adenomyosis
Comparison of the Operation and Medical Treatment of Endometriosis and Adenomyosis
Endometriosis (including adenomyosis) is one of the most common gynecological diseases among women of childbearing age. Common symptoms such as menstrual pain, excessive menstrual flow, infertility, chronic lower abdominal pain…
- Trial name
- NCT03778359
- Testing
- Leuprorelin, Levonorgestrel, Dienogest
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Endometriosis, Pelvic Pain
The Safety and Effectiveness of Surgery With or Without Raloxifene for the Treatment of Pelvic Pain Caused by Endometriosis
Many women with lower abdominal pain have endometriosis. Endometriosis is a condition in which the lining of the uterus (endometrium) is found outside of the uterus. The diagnosis of endometriosis is usually made at surgery.
- Trial name
- NCT00001848
- Testing
- Raloxifene
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis
Dopamine Receptor Agonist Therapy for Pain Relief in Women Suffering From Endometriosis: A Pilot Study
The proposed pilot study will estimate the efficacy and safety of a novel therapeutic agent, cabergoline, with a clinical standard therapy, norethindrone acetate, for the treatment of endometriosis-associated pain in young women…
- Trial name
- NCT02542410
- Testing
- Cabergoline, Norethindrone acetate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Pregnancy Related, Pregnancy Complications
Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
The Relugolix Pregnancy Registry is a prospective, observational cohort study designed to evaluate the association between relugolix-containing therapy exposure during pregnancy and subsequent maternal, fetal, and infant…
- Conditions
- Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk
- Trial name
- NCT05739123
- Testing
- Relugolix-Containing Product
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Endometriosis, Probiotics
The Role of Probiotics in the Treatment of Endometriosis (ProMetrioS): a Randomised Double-blinded Placebo-controlled Cross-over Trial
ProMetrioS is a randomised blinded placebo-controlled cross-over trial investigating the effect of specific multistrain probiotics in patients with endometriosis.
- Trial name
- ProMetrioS (NCT06929364)
- Testing
- Omni Biotic Stress
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- The Gut Microbiome Center (Centar za crijevni mikrobiom)
Pelvic Pain Syndrome, Endometriosis
The Good Pain Consultation in Endometriosis.
This PhD project investigates the effect of "the good pain consultation" and early integration of biopsychosocial pain education with current standard management of endometriosis.
- Conditions
- Pelvic Pain Syndrome, Endometriosis, Dysmenorrhea, Adenomyosis
- Trial name
- NCT07205614
- Testing
- pain consultation, biopsychosocial pain education + usual care, Usual Care
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Sorlandet Hospital HF
Women in the Reproductive Age Group, Undergoing Laparoscopy for Pelvic Pain and/or Infertility
Endometrial Biopsy as Diagnostic Method for Endometriosis and Endometrioma
Our aim was to evaluate the efficacy of examining endometrial biopsy specimens for nerve fibers as a diagnostic test for endometriosis and endometrioma in a double-blind comparison with diagnostic laparoscopy.
- Conditions
- Women in the Reproductive Age Group, Undergoing Laparoscopy for Pelvic Pain and/or Infertility, Not Currently Receiving Hormonal Treatment for at Least 3 Months Prior to Laparoscopy.
- Trial name
- NCT01022372
- Testing
- Endometrial biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Endometriosis
The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial
The purpose of this study is to determine whether a regimen of norethindrone acetate + placebo or norethindrone acetate + conjugated estrogens is superior in maintaining skeletal health and quality of life in adolescents treated…
- Trial name
- NCT00474851
- Testing
- Norethindrone acetate + estrogens
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Endometriosis
IUD and Norethindrone Acetate for Treatment of Endometriosis
Endometriosis is the most common reproductive disease afflicting young women, often leading to debilitating chronic pelvic pain and impaired quality of life.
- Trial name
- NCT04948489
- Testing
- norethindrone acetate (NETA)
- Where
- United States
- Sponsor
- Boston Children's Hospital
Endometriosis Rectovaginal Septum
Laparoscopic Surgery for Severe Recto-vaginal Endometriosis
To determine the quality of life following the radical excision of recto-vaginal endometriosis.
- Trial name
- NCT02471443
- Testing
- Surgery for severe endometriosis
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Endometriosis, Pelvic Pain
Machine Learning for Early Diagnosis of Endometriosis(MLEndo)
The project aims to create a large prospective data bank using the Lucy medical mobile application and collect and analyze patient profiles and structured clinical data with artificial intelligence.
- Conditions
- Endometriosis, Pelvic Pain, Infertility, Female
- Trial name
- MLEndo (NCT06147687)
- Testing
- Self reported data collection
- Where
- 2 sites in Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Endometriosis (Diagnosis)
TENS for Endometriosis Pain in Adolescents and Young Adults
The goal of this project is plan to investigate the utility of Transcutaneous Electrical Nerve Stimulators (TENS) for the reduction of pain and the improvement of quality of life in adolescents and young adults with chronic…
- Trial name
- NCT06914752
- Testing
- TENS
- Where
- United States
- Sponsor
- Boston Children's Hospital
Endometriosis
Treatment of Chronic Pelvic Pain Due to Endometriosis by Transcutaneous Auricular Vagus Nerve Stimulation
6-10% of women of childbearing age suffer from endometriosis, which is mainly manifested by dysmenorrhea, non-menstrual pelvic pain and dyspareunia.
- Trial name
- Stim-Endom (NCT04177511)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Hopital Foch
Migraine, Endometriosis
Endometriosis and Migraine
This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls.
- Trial name
- EMC (NCT06785129)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Endometriosis
Activation of the Sphingosine-1-phosphate (S1P) to S1P1 Receptor Subtype (S1PR1) Axis in Patients With Endometriosis: Identification of Potential Relevant Biomarkers to Diagnose and Treat
Patients seen at the SLUCare Center for Endometriosis (including those with or without pain) undergoing laser excision surgery for known or suspected endometriosis will be recruited for the study.
- Trial name
- S1P1 (NCT02973854)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- St. Louis University
Endometriosis
Visanne Study to Assess Safety in Adolescents
A clinical trial which was designed to demonstrate the safety and efficacy of Visanne (approved in endometriosis for adults) in the adolescent population.
- Trial name
- VISADO (NCT01283724)
- Testing
- Dienogest (Visanne, BAY86-5258)
- Where
- 36 sites in Austria, Czechia and 4 more
- Volunteers
- 111 people
- Sponsor
- Bayer
Pelvic Pain, Endometriosis
Endometriosis Pain
Aim 1. To determine the factors contributing to pain in patients with chronic pelvic pain with and without endometriosis Aim 2. To determine the changes following endometriosis lesion removal surgery in pain and sex hormone…
- Trial name
- NCT06101303
- Testing
- Psychophysical assessment, Psychophysical assessments of experimental pain, Blood, urine and saliva samples
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Washington University School of Medicine
Endometriosis
Postoperative Cyclic Oral Contraceptive Use for the Prevention of Endometrioma Recurrence
Ovarian endometriotic cyst (endometrioma) is one of the most common endometriotic lesions, and conservative laparoscopic surgery is the treatment of choice. However, the recurrence after surgery is common.
- Trial name
- NCT01092494
- Where
- South Korea
- Volunteers
- 232 people
- Sponsor
- Samsung Medical Center
Endometriosis, Pelvic Pain
The Effectiveness of Lng IUD for Treatment of the Patient Undergone Conservative Surgery for Pelvic Endometriosis
this study is to determine whether the frequency and severity of pelvic pain or dysmenorrhea are reduced in women with symptomatic endometriosis in whom a Lng IUD is inserted after operative laparoscopy compare with those treated…
- Conditions
- Endometriosis, Pelvic Pain, Dysmenorrhea
- Trial name
- NCT00455845
- Testing
- Levonorgestrel IUD
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University